BSc Biochemistry Sem V 2014 2015 2015 Paper 4 Question Paper - Mumbai University | munotes

Questions asked in this paper

• (2) Figures to the right indicate full marks

1. Q1 (A) Pill in the blanks (any three)
   • (i) immunity is the less specific component of immune have a multilobed nucleus
   • (iii) Activation of play a central role in astivation of cell mediated and humoral immunity
   • (iv) The well accepted theory to explain specificity of antibodies is
   • (v) Adaptive immunity is of the following type comprise a group of proteins by virus infected cells
   • (B) Explain the following (any one) 2
   • (i) Phagocytosis (ii) Anatomical barriers of immune response
   • (C) Answer the following (any one) 4
   • (D) Elaborate on (any one) 6
   • (i) Humoral and Cell immunity
2. Q2 (A) Fill in the blanks (any 3 marks
   • (i) On electrophoretic Separation, antibodies
   • (ii) The light ch of an antibody could be
   • (iii) The antibody to exist in a pentameric state is
   • (iv) Mercaptoethanol helps in reduction of
   • (v) Igs present on an unstimulated B are Expression of light chain requires rearrangement of gene se Rearrangement of heavy chain gene segment Classes of antibodies
   • (D) Elaborate on (any one) 6 Structure of antibody
3. Q3 Fill in the blanks (any three) 3 marks
   • (i) Inborn errors of metabolism are
   • (ii) Reduced oxygen carrying capacity is also known as
   • (iii) Atherosclerosis leads to the formation of
   • (iv) In Von Gierke’s disease there is deficiency of
   • (b) Glucose-6-phosphatase
   • (c) Glucose-6-aldolase
   • (v) Sickle cell anaemia occurs due to a defect in genes
   • (vi) The occurrence of iron deficiency in anaemia is thalassemia
   • (a) Less than (b) More than (c) Equal to
   • (B) Explain the following (any one) 2
   • (C) Write short notes on (any ore) :— 4
   • (i) Enlist the biochemical features of Glycogen Storage Disease type I
   • (ii) Explain factors increasing the chances of having atherosclerosis
   • (D) Elaborate on (any ene) :— 6 Fill in the blanks (any three) :— 3
   • (i) growth of cell denotes
   • (ii) Benign tumours are characterized as endothelial tumour is
   • (iv) The study of cancer is
   • (v) Migration of cancer cells in the human body is known as
   • (a) Metakinetics (b) Metabolomics (c)
   • (vi) Malignant tumours are
   • (B) Explain the following (any one) :— 2
   • (C) Write short notes on any one :—
   • (i) Progression of cancer Therapy of Cancer
   • (D) Discus in detail the following (any one) :— 6
   • (i) Causes of malignancy
   • (ii) Physiology of a cancer cell
   • (A) Attempt any one of the following -— 3
   • (i) Characteristics of inflammation
   • (B) Discuss in detail (any one) :— 3
   • (i) Monoclonal antibody
   • (C) Explain the following (any one) 3
   • (D) Answer any one of the following :— 3
   • (i) Causative factors of carcinogenicity (ii) Types of tumours
   • (E) State true or false (any :— 3
   • (i) NK cells do not nave T cell receptors that can recognise antigen
   • (ii) Sickle cell anaemia can be completely cured by intake of iron supplements
   • (iii) Substances that can be recognized immunoglobulins are called antigens
   • (iv) All mutagens are carcinogens
   • (v) All immunogenic molecules are antigenic in nature
   • (vi) Thalassemia can occur due to the deficiency of vitamin

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