BSc Biochemistry Sem V 2018 19 Oct 2018-19 BIO CHEM BIOCHEMISTRY IV IMMUNOLOGY AND PATHOPHYSIOLOGY Question Paper - Mumbai University | munotes

Questions asked in this paper

1. Q1 All the questions are compulsory. Choice is internal
2. Q2 Figures to the right indicate full marks
3. Q3 All questions carry equal marks Fill in the blanks: (any three) 3
4. Q1 Adaptive immunity is line of defence li) cells are responsible for cell mediated immune response lil) is a primary lymphoid organ
   • iv) Kuffer cells are a type of Define and explain any one of the following: 3
   • i) Effector Cells Write a detailed note on any one : 6
5. Q1 Cells of immune system
   • ii) Cytokines Attempt any one: 8
6. Q1 Elaborate on barriers of innate immune response
   • ii) Discuss the different secondary lymphoid organs Fill in the blanks: (any three) 3
   • i) Antibodies are in nature
   • ii) There are types of heavy chains ili) Kappa is a type of chain
   • iv) The first secreted antibody is
7. Q2 B) In an antibody molecule explain the role of any one of the following: 3 marks
8. Q1 linkages
9. Q2 C) Write a detailed note on any one : Types of peptide chains in an antibody 6 marks
10. Q2 D) Answer any one of the following: 8 marks
11. Q1 Discuss the mechanism of VDJ gene rearrangement Explain in detail with the aid of a labelled diagram the structure of an antibody Fill in the blanks: (any three) 3
12. Q1 Glycogen Storage I disorder is inherited as an autosomal trait
    • ii) Thalassemia is a defect in protein ili) Patients with Tay Sachs disease generally die by years of age
    • iv) In ferritin, iron is in oxidation state
13. Q3 B) Define and explain any one term: 3 marks
    • i) Von Gierke disease (ii) Inborn error of metabolism
14. Q3 C) Write a short note on any one: 6 marks
15. Q3 D)_ In detail answer any one: 8 marks
16. Q1 Discuss the causes, biochemical changes and symptoms of atherosclerosis
    • ii) Write an informative note of sickle cell anaemia Fill in the blanks: (any three) 3 li) are cancers of epithelial cells uli) The shape of cells which have lost control of cell division is generally
    • iv) radiations are carcinogenic
17. Q4 B) Define any one: 3 marks
    • i) Sarcoma
    • ii) Tumour
18. Q4 C) Write detailed notes on any one: 6 marks
19. Q4 D) in detail any one: 8 marks
20. Q1 Discuss the treatment modalities that can be used for controlling cancer
    • ii) Describe the causes of cancer
21. Q5 Write notes on: Biological functions mediated by antibodies 16 marks
    • ii) Digestion of antibody by pepsin ii)
    • iv) Cellular changes occurring in a cancer cell
    • iv) Malignant and benign tumours
22. Q5 B) State true or false: (any four) 4 marks
23. Q1 are a type of granulocytes
    • ii) Innate immunity takes around a week to develop
    • iii) Effector B-Cells are called CTL
    • iv) cell anaemia, Glutamic acid at 16" position is replaced by valine
    • v) UV light is used for cancer therapy
    • vi) Nat ions play a role in pathophysiology of hypertension

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