BSc Biotechnology Sem III ATKT 2017-18 ATKT Biotech Immunology Question Paper - Mumbai University | munotes

Questions asked in this paper

• 1. Attempt all questions

1. Q2 All questions carry equal marks
2. Q4 Use of log tables and non-programmable calculator is allowed
3. Q5 For Q 2,Q 3 and Q 4 attempt A and BOR Cand D
4. Q1 Do as directed (Any fifteen) 15 marks
5. Q1 Give an example of a granulocyte
6. Q2 Name the dendritic cell specific to skin
7. Q3 What is the site for T cell maturation?
8. Q4 Give the full form of MALT
9. Q5 Fill in the blank: CD 8* also called
10. Q6 Give an example of a cell that contains vesicles with histamine
11. Q7 State true or false: C4b2a is also known as C5 convertase
12. Q8 State true or false: Pro- T cells express CD 7 on their cell surface
13. Q9 Fill in the blanks: Peptide binding cleft of MHC class lis made of ___ and
14. Q10 State true or false: MHC class II is seen on the surface of all nucleated cells
15. Q11 State true or false: TCR bind antigens in association with MHC
16. Q12 State true or false: Ty cells secrete cytokines to activate B cells
17. Q13 Define: Membrane distal domain of MHC What are memory T cells?
18. Q15 Define: Agglutination reaction
19. Q16 Give an example of a radioisotope used to tag antibodies in RIA
20. Q17 State one application of Coomb’s test
21. Q18 State true or false: Identification of a specific protein in a complex mixture of proteins can be accomplished by Western blotting
22. Q19 State true or false: Flow cytometer is used to determine the type and number of white blood cells in blood samples
23. Q20 State one application of indirect ELISA
    • Q. P. Code: 23079 Discuss the structure and role of lymph node as a lymphoid organ. 08
24. Q2 B_ What is hematopoiesis? Diagrammatically explain the process. Describe the alternate pathway for complement activation. 08 What are mononuclear phagocytes? Discuss brief their structure and 07 Describe the structure and functions of TCR complex. 08 7 marks
25. Q3 B_ Using a neat labelled diagram give the overview of B cell development Describe the exogenous pathway for antigen presentation by MHC. 08 Enlist the different types of T cells and describe their functions in brief. 07 Explain the steps involved in ELISPOT assay. 08 7 marks
26. Q4 B _ Describe two dimensional immunoelectrophoresis. What is complement fixation test? Describe the technique. 08 Describe passive agglutination and give its application. 07 7 marks
27. Q5 Write short note on any three of the following d Technique of direct immunofluorescence Technique of ELISA using chemiluminescence 15 marks

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