BSc Biotechnology Sem III 2022 2023 Oct 2023 IMMUNOLOGY Question Paper - Mumbai University | munotes

Questions asked in this paper

• 1. Attempt all questions

1. Q2 All questions carry equal marks
2. Q4 For Q2,Q3 and Q 4 attempt A and B OR C and D Do as directed (Any fifteen) 15 Name the largest lymphatic vessel Name the macrophage like cell in the lung 3 Name the congenital birth defect in humans in which thymus fails to develop
3. Q4 Define naive cells Which cell develops into macrophage after settling in tissues?
4. Q6 Name the C3 convertase in the lectin complement pathway Give the significance of factor H
5. Q8 State true false: HLA codes for MHC
6. Q9 What is ITAM?
7. Q10 State true/ false: Invariant Chain is involved in the endocytic pathway for antigen Give an example of a co-receptor of a T cell State true/ false: T helper cells secrete IL2 after activation State trve/ false: TCR is a homodimer made of alpha chain
8. Q14 Define: Thymus Independent Antigens
9. Q15 Give one example of substrate used in ELISA
10. Q16 Give One Example of complete Antibodies When was radioimmunoassay developed?
11. Q18 What is the full form of ELISA?
12. Q19 State true/false: In a flow cytometer the particles are analyzed all at a time
13. Q20 molecules are manufactured by the body that help fight antigens
    • a) antigen
    • d) antibody SYBTSEMIII IMMUNOLOGY 75MARKS 2%HRS QzA_ Give a brief account on lymph node and spleen. 08 Describe the alternative complement pathway in detail. 07
14. Q2 C_ Write a note on regulation of the complement system, 8 marks
15. Q2 D__ Describe the mucosal associated lymphoid tissue in brief 7 marks
16. Q3 A_ Write a note on the experimental evidence proving Self MHC restriction of T-cell. the cytosolic pathway for Antigen processing and presentation. 07 8 marks
17. Q3 C the process of activation of T cells. Describe the structure of BCR with its co-receptors, 07 Describe Immunoprecipitation reactions with suitable example 08 Whatare the applications of flow cytometry in immunodiagnostics? 07 Whatisa cross-reactivity in immunclogy? 08 8 marks
18. Q4 D_ Explain complement fixation test. short note on any three of the following 15 7 marks
    • a) Mononuclear phagocytes
    • b) Complement Deficiencies
    • c) B- cell maturation
    • e) Blood Grouping

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