BSc Biotechnology Sem III 2022 2023 Oct 2023 MOLECULAR BIOLOGY Question Paper - Mumbai University | munotes

Questions asked in this paper

• 1. Attempt all questions

1. Q2 All questions carry equal marks
2. Q4 For Q 2, Q3 and Q 4 attempt A and B OR C and D
3. Q1 Do as directed (Any fifteen) 1 What is alternative splicing? 2 What are the housekeeping gene? 3 What is the significance of CII gene in the lysogenic pathway of bacteriophage 4, What is the significance of Beta galactose? 15 marks
4. Q5 What is genetic switch?
5. Q6 What is the significance of RISC in the RNAi mechanism?
6. Q7 Define: Constitutive gene?
7. Q8 RNA is direction
8. Q9 What do you mean by non-template strand in RNA synthesis? State true or False: In bacteria, proteins other than the DNA are involved in the unwinding of DNA for transcription
9. Q11 Give the consensus sequence of Pribuiow box
10. Q12 Give the significance of sigma factor
11. Q13 What do you mean by core promoter complex Give the significance of the following biomolecules in translation VCD/ 20 2 2.SYBT SEM III MOLECULAR BIOLOGY 75 MARKS 2%HRS
12. Q2 A_ Elaborate on transcription initiation in prokaryotes, 8 marks
13. Q2 B Discuss the different types of termination of prokaryotic transcription. 7 marks
14. Q2 C Explain the stepwise events involved in the formation of pre initiation complex in eukaryotic transcription 8 marks
15. Q2 D_ Discuss the processing of premature mRNA to mature mRNA. The initiation of translation is coordinated by various biomolecules. Justify the 08 statement with suitable schematic representation, the various proteins required for extension of translation. Explain the 07 extension of translation in brief 7 marks
16. Q3 C Explain the aminoacylation of t-RNA in prokaryotes with suitable schematic 0s statement with suitable schematic representation
17. Q4 A regulation of gene expression in phage lambda by lysogenic pathway. 8 marks
18. Q4 B Give an account of RNA interference. 7 marks
19. Q4 C What is chromatin remodeiing? Explain it. Give an account of lac operon and its positive control. 07 8 marks
20. Q5 Write a short note on any three of the foliowing 15 marks
    • a. RNA modification at the end, Coupled transcription and translation
    • d. Properties of genetic code i
    • e. Molecular attenuation of trp operon

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