BSc Biotechnology Sem V 2023 2024 Oct 2024 BIOTECH CELL BIOLOGY Question Paper - Mumbai University | munotes

Questions asked in this paper

• 1. Attempt all questions

1. Q2 All questions carry equal marks
2. Q4 Use of log tables and non-programmable calculators is allowed
3. Q1 a. Select the correct alternative: (Any Six) 6 marks
4. Q1 The resting
   • a. Gl b. G2 c. GO d.S
5. Q2 One of the major differences between a standard cell cycle and an embryonic cell
   • a. standard cell cycle is prolonged
   • b. Embryonic cell cycle is prolonged During cell cycle the cell to exit from mitosis requires
   • a. cdk activation
   • b. cdk inactivation
   • c. synthesis of cyclin
   • d. degradation of cyclin
6. Q4 is an example of a broad specificity growth factor in cell growth of
7. Q5 Yeasts are used as models for cell cycle studies for all reasons EXCEPT
   • a. They are unicellular, so easily maintained
   • b. They reproduce as fast as Bacteria
   • c. They are well suited for cloning studies
   • d. They are suitable for Microinjection studies
8. Q6 fission yeast the more stringent size check point is at The inhibitory kinase in yeast cell cycle is
9. Q8 Apoptosome consists of
   • a. Cytochrome C+apafl
   • b. Cytochrome C 9
   • d. Cytochrome C +procaspase 9
10. Q9 The unique feature of cell cycle in multicellular animals is that
    • a. the cell cycle is simple and can be easily predicted
    • b. the cell cycle is more complex and gene duplication has created many
    • c. the cell cycle can be completely overwritten by environment
    • d. the cell cycle cannot be controlled
11. Q1 b. Answer the following questions: (Any Two) 14 marks
12. Q1 Discuss in detail cell cycle regulators and checkpoints
13. Q2 Diagrammatically explain the ligand-receptor-mediated pathway of apoptosis
14. Q3 With reference to embryonic cell cycle discuss
    • a. MPF composition and function
    • b. Two experimental evidences of cytoplasmic regulator- MPF
15. Q2 a. Select the correct alternative: (Any Six) 6 marks
16. Q1 Receptors present inside the cytoplasm are called receptors
17. Q2 Gprotein consists of protein subunits
18. Q3 is present in small amounts in the inner half of plasma membrane lipid
19. Q4 is an example of receptors
20. Q5 PDGF receptors are examples of receptors
    • c. nuclear d. Neutral
21. Q6 _ controls the direction of flagellar rotation
22. Q7 signalling, the cell signals to itself Inducible NOs are synthesized by
23. Q9 receptors are involved in rapid synaptic signalling between the nerve cells and other electrically excitable target cells
24. Q2 b. Give an account on the following questions: (Any Two) 14 marks
25. Q1 Activation of Inositol phospholipid signalling pathway
26. Q2 Classes of enzyme coupled receptors
27. Q3 Action of extracellular signal molecules over short and long distance
28. Q3 a. Select the correct alternative: (Any Six) 6 marks
29. Q1 A single neural crest cell can differentiate into any of several different cell types is
30. Q2 Diagram of an organism at an early stage of development that indicates the fate of each cell or region at a later stage of development
31. Q3 Zebrafish is a preferred model organism in developmental biology because:
    • a. It is the closest mammalian model organism to humans
    • b. It has a transparent embryo
    • c. It undergoes external fertilization
    • d. its embryo develops outside the female's body
32. Q4 A fundamental process of animal embryogenesis that employs cellular rearrangements and movements to reposition and shape the germ layers
33. Q5 | Which among the following is NOT a derivative of the endoderm germ layer?
34. Q6 is the first step in defining specific regions of the developing
35. Q7 The morphogenic movement involves the splitting of one cell sheet into two or more parallel sheets
36. Q8 The portion of the Drosophila body plan which will produce the tail is called:
37. Q9 of the following will be able to form placenta and extra-embryonic tissues Discuss the following: (Any Two) 14
38. Q1 With reference to developmental biology:
    • a) Zygote and blastula b) Embryonic stem cell
39. Q2 Concept of Fate map, Methods of Construction of fate map, and significance
40. Q3 With reference to gastrulation: Types of cellular movement and Germ layers
41. Q4 a. Select the correct alternative: (Any Six) 6 marks
42. Q1 The following are the characteristics observed in cancerous growth. Select the
    • a. defective apoptosis
    • c. Establishment of colonies in distant organs
43. Q2 A gradual accumulation of mutations in a number of different genes leads to a
44. Q3 is a cancer associated gene family that regulates apoptosis
45. Q4 The tendency of tumor cells to take high uptake of glucose for rapid proliferation of cancerous cells is termed as
46. Q5 is possible to associate new formation with the epigenetic silencing of specific genes
    • c. euchromatin d. heterochromatin
47. Q6 the case of , the cancer-causing alleles produced are
48. Q7 Given below are the steps involved in metastasis. Choose the incorrect one:
49. Q8 Angiogenesis is
    • b. atype of cancer
50. Q9 In assay to mimic liver metabolism activating extract prepared from rat liver cells is mixed with the carcinogen
51. Q4 b. Attempt the following questions: (Any Two) 14 marks
52. Q1 With reference to hallmarks for cancerous growth, discuss
    • a. Cancer cells escape built-in limit to cell proliferation
    • b. Loss of contact inhibition by cancerous cells Explain cancer-critical genes and their two classes. Add a note on the role of p53 in
53. Q3 Classification of cancers based on tissues and cell types
54. Q5 Write Short notes on the following: (Any Four) 20 marks
    • a. M-phase
    • b. Caspases and its targets
    • c. Receptor down regulation in slow adaptation
    • d. Any one model organisms in developmental biology
    • e. Contributions of viruses in human cancer
    • f. Changes in Lifestyle and cancer

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