B.Sc. (Biotechnology) Sem V 2022 2023 Nov 2023 CELL BIOLOGY Question Paper - Mumbai University | munotes

Questions asked in this paper

• Attempt all questions

1. Q2 All questions carry equal marks
2. Q4 Use of log tables and non-programmable calculator is allowed
   • a. Select the correct alternative (Any six) 06
3. Q1 The time interval between the DNA replication and mitosis is called the phase of the cell cycle. a. M b.S d. G2
4. Q2 Saccharomyces cerevisiae is also called yeast
5. Q3 enzymes are involved in apoptosis and are a member of cysteine proteases
6. Q4 is an essential component of MPF and is found in all eukaryotic cells
7. Q5 yeast has rod-shaped cells that grow by elongation at their ends. After mitosis, the cell divides in two by laying down a septum at the center of the rod
8. Q6 | What happens If an oocyte in interphase is injected with cytoplasm from an oocyte in
   • a. it drives the recipient oocyte into Mitosis
   • b. it drives the recipient oocyte into DNA replication
   • c. the recipient oocyte in interphase
   • d. it does not affect the recipient’s oocyte
9. Q7 The exit from mitosis fora cell requires
   • a. synthesis of cyclin b. degradation of c. cdk activation
   • d. cdk inactivation
10. Q8 This G1 checkpoint is called in budding yeast
11. Q9 — In intrinsic pathway an apoptosome consists of
12. Q1 b. Answer the following questions: (Any Two) 14 marks
13. Q1 Give the overview of the cell cycle and its phases in eukaryotes
14. Q2 Explain the extrinsic pathway of apoptosis with a diagram
15. Q3 With reference to the early embryonic cell cycle and the role of MPF discuss
    • a. Differences between the standard cell cycle and the Embryonic cell cycle
    • b. Structure composition, the role of MPF, and oscillations of MPF
16. Q2 a. Select the correct alternative (Any six) 6 marks
17. Q1 between the cells is mediated by signalling molecules which bind on the plasma membrane receptors
    • a. extracellular mitochondrial
18. Q2 ligands have their receptors on
19. Q3 is the activity of
    • d. Extracellular matrix
20. Q4 enzyme causes cyclization of AMP to cAMP
21. Q5 is example of enzyme coupled receptors
22. Q6 The phosphorylation of activates the protein which causes clockwise rotation
23. Q7 is one of the three layers of interconnected units of computer-based neural
24. Q8 A G-protein-linked receptor has transmembrane segments
25. Q9 When deprived of the signals, the cell-activates a suicide program and kills itself
    • a. apoptosis b. mitosis c. meiosis d. initiation of tumors
26. Q2 b. Give an account on the following questions: (Any Two) 14 marks
27. Q1 Autocrine, and paracrine signaling molecules with suitable examples for each
28. Q2 Structure of G protein-coupled receptors with the help of a neat diagram
29. Q3 JAK-STAT signaling pathway with the help of a neat diagram
30. Q3 a. Select the correct alternative (Any six) 6 marks
31. Q1 The Fertilized egg cell is also called a Morphogenic movement involves the local inward buckling of an
32. Q3 one of the following is the source of embryonic stem cell
33. Q4 The mouse preferred model organism in developmental biology because:
    • a. It is the closest mammalian model organism to humans
    • b. Option model organism should have huge adult size
    • c. Model organisms should not be easily available
    • d. Model organisms should be expensive
34. Q5 is NOT a derivative of the endoderm germ layer
35. Q6 are special molecules which play a very important role during oocyte maturation, in the female's ovary
    • d. nuclear determinants
    • a. Should have a long life cycle b. should have a size
    • c. should be easily available. d. should be inexpensive
36. Q8 Which one of the following is an artificial marking technique used in the construction of a fate map?
37. Q9 will form placenta and extra-embryonic tissues embryo Discuss the following: (Any Two) 14
38. Q1 Importance of model organisms in developmental biology
39. Q2 Fate map: Construction and uses
40. Q3 Overview of Developmental biology and contribution of various disciplines in the emergence of developmental biology
41. Q4 a. Select the correct alternative: (Any six) 6 marks
42. Q1 are cancers arising from epithelial cells Cells defective in escape apoptosis and promotes cancer
43. Q3 Genes that encode proteins that inhibit excessive cell proliferation are called 4, In , the formation of new blood vessels fora tumor to ensure adequate blood supply to get sufficient oxygen and nutrients
44. Q5 is associated with liver cancer or hepatocellular carcinoma
45. Q6 is a chemotherapeutic drug that binds to abnormal proteins in cancer
46. Q7 genes are mutated in a wide range of human cancers and are one of the most important. examples of cancer-critical genes
47. Q8 gene is.a gene
    • c. apoptotic d. metastatic
48. Q9 Penetration of cell into a blood vessel and the exit of the same elsewhere in the body to grow new site small clump at first before called
49. Q4 b. Describe the following questions: (Any Two) 14 marks
50. Q1 Cancer cells are a clone descended from a single abnormal cell
51. Q2 Role of p53 in controlling cancer Short notes on the following: (Any. four) 20
    • a. Caspases and their targets
    • b. Role of Growth Factors in the proliferation of Mammalian Cells
    • d. Slow adaptation
    • e. Cytoplasmic determinants
    • f. Role of viruses in cancer

Read from the scan above, so a character or two may differ. The scan is the original.