BSc Biotechnology Sem V 2016 17 2016-17 Biotechnology I Cell Biology ,Medical Biotech & Biostatistic Question Paper - Mumbai University | munotes

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1. Q2 All questions carry equal marks
2. Q4 Use of log books and non-programmable calculator is allowed
3. Q1 a) Define any three of the following 3 marks
   • iii. DAG
   • iv. Calmodulin
4. Q1 b) Discuss any two of the following 12 marks
   • i. Structure of GPCR and G proteins
   • ii. Significance of nuclear receptors in cell signaling
   • iii. Use fo binding assays to determine Kd values of receptors
   • iv. Endocrine signaling in comparison with synaptic signaling
5. Q2 a) Name of the following (Any Three) 3 marks
   • i. The phase of cell cycle in which DNA duplication occurs
   • ii. Example of cells that normally do not divide but can be induced to begin DNA synthesis with
   • iii. Process of cell death due to acute injury that spill their contents
   • iv. A multiprotein complex formed in cytosol during intrinsic pathway of apoptosis Process by which cancer cells invade blood vessels and are carried to other tissues Vi. Mechanisms that.a cell possesses that halts the progress of the cell cycle
6. Q2 b) Give an account of any two of the following 12 marks
   • i. Stages of cell cycle Receptor mediated pathway of apoptosis
   • iii. Maturation promoting factor and its role in cell cycle
   • iv. Role of caspases and their targets in apoptosis
7. Q3 a) directed (Any three) 3 marks
   • i. Define Protoplast
   • ii. Give one. example of drug used to treat systemic mycoses ili. State True of False- In immunocompromised patients, bacteriostatic drugs may be less efficacious
   • iv. the blank- The MICis the concentration of drug that kills the Name.the microorganism that produces Polymyxins Vi. Give one example of B lactam antibiotic
   • Q.P. Code :01237
8. Q3 b) Answer any two of the following 12 marks
   • i. Explain the mode of action of antimetabolites giving two examples
   • ii. What is selective toxicity? Explain with the help of two examples
   • iii. Elaborate on the mechanisms of drug resistance
   • iv. Give an account of mechanism of action of Vancomycin and Bacitracin Do as instructed (Any three) 03
   • i. Calculate median :-12,14,5,6,17,8,21,45,34,10,11
   • ii. State true or false:- Z test is parametric test used to test significance of mean for sample size more
   • iii. is the positive square root of the arithmetic mean of the squares of deviations of the various items from the arithmetic mean of the series
   • iv. Explain perfect positive correlation Vv. State Null hypothesis
   • vi. Choose the correct option: The ratio between observed results is represented by
   • a) Theta Value
   • b) Chi-square
   • c) Variance ratio
   • d) None of these
9. Q4 b) Attempt any two of the following 12 marks
   • i. and explain the representation of data using diagrams and graphs
   • ii. Discuss: Dependent and Independent variables, regression lines and. equations with reference to
   • iii. The heights of 10 children selected at random from a given locality had a mean of 63cm. anda variance of Using t-test at 5% level of significance the hypothesis that the children of the given locality are on the average less than 65 cm. (Given t
   • iv. Calculate the coefficient of correlation to establish the relationship between the length of pea pods and number of each pod Write short notes on any three of the following 15
   • i. Desirable properties of a new antimicrobial agent
   • ii. Mode of action of Quinolones:
   • iv. Role of morphogens in cell signaling Vv. Types of extracellular messengers

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