BSc Biochemistry Sem VI 2018 19 May 2018-19 BIO CHEM BIOCHEMISTRY PAPER II NUTRITION & PHARMCOLOGY Question Paper - Mumbai University | munotes

Questions asked in this paper

• Please check that you have received the correct question paper

1. Q1 All questions are compulsory. Choice is internal
   • ii) Figures to the right indicate full marks Draw structures and diagrams wherever necessary
2. Q1 A) the blanks: (Any three) mg water-soluble vitamins, 2 mg potassium and sodium will provide li) Bomb calorimeter measures the _ value of different food ili) provides double the energy provided by carbohydrates or proteins 3 marks
   • iv) Jaggery is a good source of
   • v) The unit of RQ is Give the physiological roles/significance of any one of the following: 3 li) Iron and zinc
3. Q1 C) Attempt any one: 6 marks
4. Q1 In detail, balanced diet for a 10 year old li) Discuss the importance of anthropometry in nutritional studies, citing any two
5. Q1 D) Attempt any one: 8 marks
6. Q1 In detail, explain the clinical significance of calcium in bone health. Also, mention its other physiological functions li) What are the different categories of nutritional status? Elaborate on each of
7. Q2 A) in the blanks: (Any three) 3 marks
8. Q1 The normal blood pressure is mm Hg il) should consume foods with alow index The fat-soluble vitamin with high antioxidant activity is A diet high in saturated fat can be linked to
   • v) More than half of our diet should comprise of Define and explain any one of the following: 3
9. Q2 C) Attempt any one: 6 marks
10. Q1 Suggest any three foods to be avoided and any three foods to be consumed by a diabetic individual. Give detailed reasons for the same li) Justify: Obstructive jaundice can be effectively managed by diet
11. Q2 D) Attempt any one: 8 marks
12. Q1 Mr Subhash is hypertensive. Elaborate in detail the diet to be followed by him li) Write an elaborate note on obesity and its dietary management
13. Q3 Fill in the blanks: (Any three) 3 marks
14. Q1 Acidic drugs are absorbed in li) substances cannot permeate membranes by passive diffusion
    • iv) If pharmacologic effect is plotted versus drug concentration for most agents, the shape of the graph is
    • v) route of drug administration is most likely to lead to first-pass effect
15. Q3 B) Define and explain any one of the following: 3 marks
    • i) Volume of distribution
16. Q3 C) short note on any one of the following: 6 marks
17. Q1 Clinical Trials
18. Q3 D) Write an elaborate note on any one of the following: 8 marks
19. Q1 Absorption of drugs via the gastrointestinal tract li) Biotransformation of drugs
20. Q4 Fillin the blanks: (Any three) 3 marks
21. Q1 If a ligand can produce maximal effects and has high efficacy it is called as ili) is the study of mechanism of action of drugs
    • iv) cAMP is the secondary messenger for
    • v) Steroidal drugs have receptor Define and explain any one of the following: 3
    • i) Antagonist
22. Q4 C) Attempt any one: 6 marks
23. Q1 Citing examples, elaborate on the action of anti-metabolites. Explain how antimetabolites are used in cancer therapy li) Discuss the mechanism of action and adverse drug reactions of salicylates
24. Q4 D) Attempt any one: 8 marks
25. Q1 Elaborate on the different drug receptor interactions. Also, note on the different receptors based on their cellular location and mechanism of action li) Explain in detail the mechanism of action and adverse drug reactions associated with: (a) Calcium channel blocker (b) Beta blocker
26. Q5 A) Answer any four of the following: 16 marks
    • i) Which are the major electrolytes in the physiological system? Explain their functions in detail
27. Q1 Discuss the different parameters for energy assessment li) Justify: Bland diet is traditionally suggested for peptic ulcer li) Define and explain dietary management and its significance ili) What is the blood-brain barrier? Explain the qualities that a drug should possess in order to cross the blood-brain barrier ili) Differentiate between: Bioavailability and bioequivalence
    • iv) Discuss the mechanism of action of penicillin
    • iv) Justify: 'Omeprazole acts as a pro-drug'
28. Q5 B) State True or False: (Any four) 4 marks
29. Q1 Complex carbohydrates provide one with short term energy li) Males have a higher BMR than females ili) At pH 9.0, morphine (a weak base containing an ionizable amine group, pKa of 7.0) would exist predominantly in the charged form
    • iv) The plasma drug concentration versus time curve for a drug eliminated by zero order kinetics is linear
    • v) Binding of drugs to albumin is irreversible Vi) Most drugs are distributed homogenously

Read from the scan above, so a character or two may differ. The scan is the original.