BSc Biochemistry Sem VI 2019 20 Nov 2019-20 ATKT BIO CHEM IMMUNOLOGY AND PATHOPHYSIOLOGY II PAPER IV Question Paper - Mumbai University | munotes

Questions asked in this paper

• 3. Figures to the right indicate marks

1. Q1 A. the blanks (any three)
   • 1) Blood grouping is an example of reaction
   • 2) The split products of C2 are
   • 3) Antibodies that aggregate soluble antigens are
   • 4) Proteins of the complement system are mainly synthesized by
   • 5) VDRL is an example of reaction
   • a) Precipitation b) Flocculation
   • 6) is an example of fluorescent dye
   • B. Define and explain (any one) 03M
   • 1) Anaphylaxis
   • 2) Radio Immunoassay
   • C. short notes on (any one) — 06M
   • 1) Schematic representation of Classical pathway Discuss the following (any one)
   • 1) Alternate pathway of complement activation and MAC
   • 2) Principle of ELISA and immunofluorescence
2. Q2 A. the blanks (any three)
   • 1) Tissues that are genetically similar are said to be
   • 2) HLA Complex is also referred to as in humans 756BE8D075687CC3F920467E9499 1 DE8
   • 3) Class II MHC presents the processed Antigen to cells
   • 4) The degree of immune response to graft varies with
   • a) Site of graft b) Type of graft c) Section of graft
   • 5) An inappropriate response of the immune system against self component is termed as
   • 6) An example of systematic auto immune disease is
   • c) Rheumatoid arthritis
   • B. Define and explain (any one) —
   • 2) Isograft
   • C. Write a note on (any one) — O6M
   • 1) Myasthenia gravis
   • 2) Structure of Class MHC-I
   • D. Attempt the following (any one)
   • 1) Define MHC polymorphism and explain the organization of MHC
   • 2) Explain the two step mechanism of allograft rejection
3. Q3 A. the blanks (any three)
   • 1) Education is a method of of AIDS
   • 2) proteins shut down the normal cellular metabolism of
   • 3) In extracellular stage, virus is called as
   • 4) HIV is the standard acronym for Human deficiency
   • 5) The enzyme reverse is significant in AIDS
   • 6) The protein subunits present in the viral capsid are called as 756BE8D075687CC3F920467E9499 1 DE8
   • B. Define and explain (any one)
   • 1) Vaccinia virus
   • C. Write short notes on (any one) — 06M
   • 1) Replication of a virus
   • 2) Genetic profile of AIDS virus
   • D. Elaborate on (any one)
   • 1) Pathogenesis of AIDS
   • 2) Mechanism of replication in Influenza virus
4. Q4 A. the blanks (any three)
   • 1) Alzheimer’s disease is a common form of
   • 2) In diabetes mellitus is a general symptom
   • a) Hypoglycemia b) Hyperglycemia c) Both ‘a’ and ‘b’
   • 3) During ageing, a subject is generally susceptible to
   • a) Less b) More c) Neither ‘a’ and ‘b’
   • 4) Ageing is characterised by changes in functions
   • 5) Alzheimer’s disease is accumulation of plaques between nerve cells
   • 6) ADH stands for Anti Hormone
   • B. Explain the following (any one) —
   • 1) Endocrine disorder
   • 2) Ageing
   • C. Write short notes on (any one) 06M
   • 2) Types of diabetes insipidus Discus in detail the following (any one)
   • 1) Theoretical concepts of ageing
   • 2) The significance of following in diabetes mellitus: 756BE8D075687CC3F920467E9499 1 DE8
5. Q5 A. Elaborate on any one of the following — 04M
   • 1) Affinity
   • 2) Important functions of complement system
   • B. Discuss in detail (any one) — 04M
   • 1) Autograft
   • C. Write a note on any one of the following — 04M
   • 1) Polio virus
   • 2) Symptoms of AIDS
   • D. Elaborate on any one of the following — 04M
   • 1) Types of Diabetes mellitus
   • 2) Causes of Alzheimer’s disease
   • E. Write True or False (any four) — 04M
   • 1) The activation of classical pathway requires Ag-Ab complex
   • 2) Xenograft exhibits the least genetic disparity
   • 3) Neuraminidase receptors vaccinia virus has the complementary structure only on epithelial cells of respiratory tract
   • 4) Complement components are synthesized in zymogen state
   • 5) Neurofibrillary tangles is very significant in Alzheimer’s disease
   • 6) Avidity of an antibody is a better measure of its binding capacity 756BE8D075687CC3F920467E9499 1 DE8

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