BSc Biochemistry Sem VI 2018 19 May 2018-19 BIO CHEM BIOCHEMISTRY PAPER II NUTRITION & PHARMACOLOGY Question Paper - Mumbai University | munotes

Questions asked in this paper

• (2) Figures to the right indicate Full Marks

1. Q1 (A) Choose the most appropriate answer (any three) : 3 marks
   • (i) RQis for a mixed diet
   • (ii) In a meal, percentage of total calories, should be obtained from fats, in adults Albumin has a chemical score of
   • (iv) Burger containing 25g carbohydrates, 10 gram and 5 gms proteins will is not a protein energy malnutrition disorder
   • (vi) Amongst the following richest source of omega fatty acids
   • (B) Define and explain (any one): 2
   • (i) Dietary fibre
   • (C) Write a note on any one: 4
   • (i) Role of sodium and calcium in nutrition
   • (ii) Measures used in Anthropometry
   • Q.P. Code : 05374
   • (D) Answer any one of the following : 6
   • (i) Discuss the factors affecting BMR
   • (ii) Write an elaborate note on balanced diet
2. Q2 (A) Choose the most appropriate answer (any three) : 3 marks
   • (i) Diabetics are at increased risk of heart disease if they also
   • (a) have low LDL cholesterol levels
   • (b) have high HDL cholesterol levels
   • (c) have high LDL cholesterol levels
   • (ii) has the highest glycemic index iii should be avoided in case of peptic ulcers
   • (iv) An individual is considered obese, when BMI is
   • (v) Food diet is served for instant energy
   • (a) high in fat and high in carbohydrates
   • (b) high in fat and low in carbohydrates
   • (c) low in fat and high in carbohydrates
   • (vi) A diet restricted in is preferred for hypertensives
   • (a) Na* (b) (c) Mg Answer any one: 2
   • (ii) What are blood sugar levels in a normal individual (i) 2 hours after meal (ii)
   • (C) Write dietary plan for any one of the following : 4
   • (D) Attempt any one of the following : 6
   • (i) Mr. Kapoor is 45 years old company executive suffering from Diabetes mellitus. Suggest a diet as per his body requirement
   • (ii) Plan a diet for Ali who suffers from hypertension
3. Q3 (A) Choose the most appropriate answer (any three) : 3 marks
   • (i) Bioavailability is dependent on
   • (a) rheological parameters of blood
   • (b) amount of a substance obtained orally and quantity of intake
   • (c) extent of absorption and hepatic first-pass effect
   • (ii) Drugs possessing can cross brain-blood barrier (iti) molecules can't permeate membranes by passive diffusion
   • (iv) Biotransfonnation of a drug involves
   • (v) Weakly acidic drugs are excreted best in urine
   • (vi) The bioavailability ofa drug is calculated with reference to drug administered
   • (B) Define explain any one of the following : 2
   • (C) Write a note on any one of the following : 4
   • Q.P. Code : 05374
   • (D) Answers any one of the following : 6
   • (i) Explain the process of drug absorption through the gastrointestinal tract and the factors affecting it
   • (ii) Discuss the methods used for bioassay
4. Q4 (A) Choose the most appropriate answer (any three) : 3 marks
   • (i) Pharmacodynamics involve the study of following EXCEPT
   • (a) adverse effects of drugs
   • (b) absorption and metabolism of drugs
   • (c) mechanisms of drug action
   • (i) "Affinity" is a measure of
   • (a) how tightly a drug binds to plasma proteins
   • (b) how tightly a drug binds to a receptor
   • (c) inhibitory potency of a drug
   • (iii) Ifan agonist can produce maximal effects and has high efficacy it is called
   • (iv) _is a second messenger of G-protein-coupled receptor
   • (v) is a beta receptor antagonist
   • (B) Define any one of the following : 2
   • (ii) Antagonist
   • Q.P. Code : 05374
   • (C) Write a note on any one of the following : 4 Mechanism of action of drugs mediated by receptors
   • (D) Answer any two of the following : 6
   • (i) Discuss the mode of action of Penicillin
   • (ii) How does a beta blocker lower blood pressure?
   • (iii) Write a brief note on adverse reactions of non-steroid anti-inflammatory
   • (iv) Discuss the action of any two drugs acting as enzyme inhibitors
5. Q5 (A) Write a brief note on any one of the following : 3 marks
   • (ii) PDCAAS
   • (B) Answer any one of the following : 3
   • (i) Justify: "Obesity can be controlled by diet"
   • (ii) Suggest how the carbohydrate intake should be modulated in conditions of
   • (C) Briefly answer any one of the following : 3
   • (i) Write a note on Therapeutic Index
   • (ii) Differentiate between bioequivalence and bioavailability
   • (D) Give brief answers to any one : 3
   • (i) Explain the mechanism by which Amlodipine elicits its effect
   • (ii) With the aid of suitable examples describe the use of drugs that act via
   • Q.P. Code : 05374
   • (E) State True or False (any three) : 3
   • (i) RDA refers to Relative Dietary Allowance
   • (ii) Fats should be avoided totally in the normal diet
   • (ii) Bioavailability is 100% for a drug administered via topical route
   • (v) Acetylation of the drug increases absorption of a drug
   • (vi) Acidic drugs are absorbed in the intestine

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