BSc Biotechnology Sem VI 2016 17 2016-17 BIOTECH Question Paper - Mumbai University | munotes

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1. Q7 All questions carry equal marks 4, of log books and non-programmable calculator is allowed
   • a) Define any three of the following 03 it Trans-autophosphorylation 1b) Discuss any two of the following of GPCR and G proteins
   • ii. of nuclear receptors in cell signaling ii, Use fo binding assays to determine Kd valués of receptors
   • iv. Endocrine signaling in comparison with synaptic signaling Name of the following (Any Three) 03 The phase of cell cycle in which DNA duplication occurs ij. Exampie of cells that normally do not divide but can be induced to begin DNA synthesis with
   • iii. of cell death due to acute injury that spill their contents iy. Amultiprotein complex formed in cytosol during intrinsic pathway of apoptosis
   • v. Process by which cancer cells invade blood vessels and are carried to other tissues vi, Mechanisms that a cell possesses that halts the progress of the cell cycle.”
   • b) Give an account of any two.of the following
   • i. Stages of cell cycle
   • ii. Receptor mediated pathway of iii, Maturation promoting its role in cell cycle
   • iv. caspases and their targets in apoptosis Do as directed (Any three). 03
   • ii. Give one example of drug used to treat systemic mycoses iii, State True of In immunocompromised patients, bacteriostatic drugs may be less efficacious the blank- The the concentration of drug that kills the
   • v. the microorganism that produces Polymyxins
   • vi. Give one example of lactam antibiotic
   • Q.P. Code :01237 ?
2. Q3 b) Answer an i y two of the following xamples the made of action of antimetabolites What is selective toxicity? Explain with the help of tw Elaborate on the mechanisms of drug resistance. cin and iv, Give an account of mechanism of action of Vancomy
3. Q4 a) Do as instructed (Any three) 45,34,10,11 Calculate median :-12,14,5,6,17,8,21,45,34,10, st significance of ii, true or false:- Z test is parametric test used to test Sig Mean for Sample Size mor ii, is the positive square root of the a of devi " the various items from tbe arithmetic mean of the series, Viations of
   • v. Nuil hypothesis
   • vi. Choose the correct option: The ratio between experimental and observed ig
   • a) Theta Value ted by
   • b) Chi-square
   • c) Variance ratio
   • d) None of these a
4. Q4 b) Attempt any two of the following
   • i. and explain the representation of data using diagrams and graphs
   • ii. Discuss: Dependent and Independent variables, regression lines and equations with reference + The heights of 10 children selected at random from locality had a Mean of 63cm, and a variance of 6.25 cm. Using t-test at 5% level of significance the hypothesis that the children of th given locality are on the average less than 65 cm. 0.05,
   • iv. Calculate the coefficient of correlation to establish the relationship between the length of Pea pog and number of seeds in each pod. Pods Length of pea pod | 40 48 No. of seeds in each pod
5. Q5 short notes on any three of the following
   • i. Desirable properties of a new antimicrobial agent
   • ii. Mode of action of Quinolones
   • iv. Role of morphogens in cell signaling
   • v. of extracellular messengers,

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