BSc Biotechnology Sem I 2023 2024 Dec 2024 MOLECULAR BIOLOGY I Question Paper - Mumbai University | munotes

Questions asked in this paper

• 1. Attempt all questions

1. Q2 All questions carry equal marks
2. Q4 For Q 2, Q3 and Q 4 attempt A and B OR C and D as directed (Any fifteen) 15
3. Q1 The common form of DNA in cells is closest in structure to Define the term
4. Q3 In DNA, the pentose sugar is ‘
5. Q4 The total amount of DNA in the haploid genome of a species is known as chromosome has the centromere at about the center, so the chromosome appears to have two approximately equal arms
6. Q6 What are two classes of nitrogenous bases present in DNA? Which enzyme is required to stabilize the separated DNA double stranded
7. Q8 Mode of DNA replication in E.Coli is:
   • a)Conservative and unidirectional a
   • b)Semi-conservative and unidirectional
   • c)Conservative and bidirectional
   • d)Semi-conservative and bidirectional
8. Q9 The unwinding of DNA is done by
   • a) in 5’ direction b) in 5’- 3’ direction
   • c)In both direction d)In neither direction
9. Q11 phase of the cell cycle does DNA replication occur? What is the significance of telomere maintenance in preserving genomic Eukaryotic DNA replication initiates at a single origin of replication. State whether True or False In the context of DNA repair, what is the function of the enzyme
   • a. Repairing thymine dimers caused by UV radiation Duration: 2% Hours Marks:75 Mutagens are substances that
   • a. Promote DNA replication b. Increase the fidelity of DNA synthesis Define point mutation
10. Q18 Induced mutation Mutations can occur spontaneously without any external factors. State whether True or False
11. Q20 in germ cells can be passed onto offspring, potentially affecting future generations. State whether True or False
12. Q2 A_ Elaborate the DNA double helix- Watson and Crick’s Model. 8 marks
13. Q2 B What is ‘nucleoside’? Draw structure of Cytosine (C) and Thymine (T), Give details of chromosome banding techniques. (Any TWO) 08 7 marks
14. Q2 D_ Elaborate the packaging of DNA into chromosomes. 7 marks
15. Q3 A Elaborate on Initiation of replication in prokaryotes. 8 marks
16. Q3 B What are DNA polymerases? and give its roles, 7 marks
17. Q3 C Explain the semi-discontinuous replication system in prokaryotes, 8 marks
18. Q3 D_ Elaborate on Initiation of replication in eukaryotes. 7 marks
19. Q4 A Give an account on different types of point mutations. 8 marks
20. Q4 B on types of Chemical mutagens which induce mutation. 7 marks
21. Q4 C Elaborate on spontaneous mutation. 8 marks
22. Q4 D - Explain Nucleotide excision repair. 7 marks
23. Q5 Write Short notes on any three of the following 15 marks
    • b. Histone and Non-histone proteins

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