BSc Biotechnology Sem IV 2018 19 Apr 2018-19 BIOTECH BIOCHEMISTRY Question Paper - Mumbai University | munotes

Questions asked in this paper

• 1. Attempt all questions

1. Q2 All questions carry equal marks
2. Q4 Use of log tables and non-programmable calculator is allowed
3. Q5 For Q 3 and Q 4 attempt A and B OR C and D
4. Q1 Do as directed (Any fifteen) 15 marks
5. Q1 Precursor amino acid for biosynthesis of
6. Q2 Synthesis of glucose from non-carbohydrate precursors is accomplished by a pathway called
7. Q3 The number of NADPH produced when one molecule of Glucose phosphate completes oxidative phase of HMP 6 marks
8. Q4 Give one example of glucogenic amino acid
9. Q5 Name one enzyme of Glyoxalate cycle that is not present in vertebrates
10. Q6 Name the organ in which urea is produced in humans
11. Q7 Give one example of energy rich compound
12. Q8 State True False: Non-oxidative deamination of histidine releases ammonia Write the equation for the reaction catalysed by following enzymes:
13. Q9 Citrate synthase
14. Q10 Glutamate dehydrogenase Name the enzyme that catalyses the conversion of following reactions:
15. Q11 Arginine to ornithine
16. Q12 Glyceraldehyde 3-phosphate to The reactions of ketone body formation occur in the matrix of
17. Q14 The absence of Hypoxanthine-Guanine Phosphoribosyl Transferase activity is observed in
18. Q15 are lipid-binding proteins in the blood which transports triacylglycerols, phospholipids, cholesterol, and cholesteryl esters between organs
    • a. Apolipoproteins b. Lipases
    • c. Carboxylases d. Chylomicrons
19. Q16 The fatty acyl group is enzymatically transferred from Carnitine to intra mitochondrial Coenzyme A by
20. Q17 Propionyl-CoA is first carboxylated to form the D stereoisomer of methyl
21. Q18 Branched fatty acids are catabolized in peroxisomes of animal cells by
22. Q19 Phosphorylation of permits hormone sensitive lipase access to the surface of the lipid droplet
23. Q20 The overall equation of Palmitoyl-CoA beta oxidation is: Discuss the reactions involved in the non-oxidative phase of the pentose 08
24. Q2 B_ Explain the regulation of glycolysis pathway. With the help of a neat labelled diagram explain the structure and 08 mechanism of rotary motor model for ATP generation Describe the Glyoxalate cycle and add a note on its significance. 07 Amino acids are degraded to metabolites that integrate into Krebs 08 Discuss the metabolic disorders associated with defects in urea cycle. 07 7 marks
25. Q3 C Describe the mechanism of Transamination of amino acids. 8 marks
26. Q3 D_ Explain the structure of glutathione and state its significance. Describe beta oxidation of saturated fatty acids. 08 Give detailed account of Purine catabolism. 07 Elaborate reactions involved in the a-oxidation of a branched-chain fatty 08 7 marks
27. Q4 D_ Explain three additional reactions involved in complete oxidation of odd 7 marks
28. Q5 Write Short notes on any three of the following: 15 marks
    • a. Metabolic disorders associated with pentose phosphate pathway
    • b. Role of coenzyme Q in ETC
    • d. Role of Cyclic AMP—dependent protein kinase (PKA) in triacylglycerol mobilization
    • e. oxidation of fatty acid

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