BSc Biochemistry Sem VI ATKT 2018-19 ATKT TYBIO CHEM Biostatistics & Bioinformatics Question Paper - Mumbai University | munotes

Questions asked in this paper

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1. Q1 All the questions are compulsory. Choice is internal
2. Q2 Figures to the right indicate full marks
3. Q3 All questions carry equal marks
4. Q1 A. Choose the MOST APPROPRIATE answer (any three): 3 marks
   • i) is an absolute measure of dispersion li) is an area diagram
   • iv) is also known as norm
   • v) percentile is the median of the data Vi) is affected by extreme values
5. Q1 B. Define and explain any one 2 marks
6. Q1 Histogram (i) Median Attempt any one 4
7. Q1 In the accounting department of bank 100 accounts are selected at random and examined for errors. The following results have been obtained. Calculate the mean Write a note on the application of biostatistics
8. Q1 D. Answer any one of the following: 6 marks
9. Q1 Write a note on Standard deviation li) Find SD for the following data on the age of patients suffering from pulmonary Age in No. of Age in No. of
   • Q.P Code: 34775
10. Q2 A. Choose the MOST APPROPRIATE answer (any three): 3 marks
11. Q1 In positive skewness of a distribution, is observed,
    • ii) PDB files can be searched by PDB id code using format
    • iii) EMBL is an example of database
    • iv) The range of probability is
    • a) -1 b) -1 to0 c) Exhaustive
    • v) distribution, Mean + 2 o will correspond to
    • vi) The probability of getting an even number in a single throw with a dice is
12. Q2 B. Define and explain: (any one) 2 marks
13. Q1 Probability
14. Q2 C. Attempt: (any one) 4 marks
15. Q1 Two students X and Y work independently on.a problem. The probability that X will solve it is 3/4 and the probability that Y will solve it is 2/3. What is the probability that the problem will be solved?
    • ii) Applications of bioinformatics
16. Q2 D. Attempt the following: (any one) 6 marks
17. Q1 a) Discuss microarray analysis and its applications
    • b) Enlist the types of databases
    • ii) a) Out of 4 boys. and 5 girls,a team of 4 students is to be selected for a quiz programme. Find the probability that 2 are girls and 2 are boys
    • b)Two dice are tossed. What is the probability that the total score is a prime number?
18. Q3 A. Choose the MOST APPROPRIATE answer (any three): 3 marks
19. Q1 The is regarded to be true in the zone of acceptance of the li) means rejection of hypothesis which should have been accepted ui) The alternative hypothesis for a left—tailed test is
    • iv) For the application of Z — test, the sample size must be 30
    • a) Smaller than b) Larger than c) Equal to
    • Q.P Code: 34775
    • v) The tests of hypotheses are also known as
    • a) Standard tests b)Parametric tests Significance tests of hypothesis v1) is a test of significance in which the direction is specified
20. Q3 B. Define and explain: (any one) 2 marks
21. Q1 Parameter (11) Hypothesis
22. Q3 C. Attempt the following: (any one) 4 marks
23. Q1 Write a note on Type I and II errors li) In a study on growth of children, one group of 100 children had a mean height of 60 cm and SD of 2.5 cm. While another group of 150 children had a mean height of 62 SD of 3 cm. Is the difference of mean between the 2 groups statistically
24. Q3 D. Attempt the following: (any one) 6 marks
25. Q1 tests of two groups of hamsters and guinea pigs gives the following Test the hypothesis that guinea pigs have better intelligence average than hamsters li) Elaborate on Z-test
26. Q4 A. Choose the MOST APPROPRIATE answer (any three): 3 marks
    • i) The degree of freedom for unpaired t — test can be calculated as
    • ii) The values of distribution are
    • ii) The two attributes under study are not associated when
    • a) 7 tab b) < C) >
    • iv) test as a test of independence is
    • v) was given by W. S. Gossett Vi) is applied for a sample with correlated observations Explain the following: (any one) 2
27. Q1 Test of goodness of fit
28. Q4 C. Attempt the following: (any one) 4 marks
29. Q1 Write a note on Test of independence
    • ii) Certain pesticide is packed into bags by a machine. A random sample of 10 bags is drawn and their contents are found to weigh (in kgs) as 50, 49, 52, 44, 45, 48, 46, 45,49 and 45. Test if the average packing weight can be taken to be 50 kg
    • Q.P Code: 34775
30. Q4 D. Attempt any one 6 marks
31. Q1 The weights of 10 tuberculosis patients on admission and at the end of 12 months of treatment with PAS plus isoniazid daily are given below. Examine whether the gain in weight is statistically significant li) An oil company has explored three different areas for possible oil reserves. The results of the test were as given below — Do the three areas have the same potential, at the 10% level of significance?
32. Q5 A. Attempt the following: (any one) 3 marks
33. Q1 Find the median of the following data on marks obtained by 100 students in li) Write a note on mode
34. Q5 B. Attempt the following: (any one) 3 marks
35. Q1 Elaborate on Normal distribution li) A card is drawn from a pack of 52 cards and then a second card is drawn. Find the probability that both cards drawn are queen
36. Q5 C. Attempt the following: (any one) 3 marks
37. Q1 For a given sample of 200 items drawn from a large population, the mean is 65 and the standard deviation is 8. Test the hypothesis that the mean of population is less Explain - Level of significance and critical value
    • Q.P Code: 34775
38. Q5 D. Attempt any one of the following: 3 marks
    • i) Two groups of 100 people each were taken for testing the use of a vaccine. 15 persons contracted the disease out of the inoculated person, while 25 contracted the disease in the other group. Test the efficiency of vaccine using 3? test li) A sample of 20 bottles has mean of 124 ml and a standard deviation of 12 ml. Is the sample representative of a large consignment with a mean of 130 ml?
39. Q5 E. Write True or False (any three) 3 marks
40. Q1 If the curve of the distribution has a longer tail towards left, it is said to be negative
    • ii) In normal distribution, mean, mode and median coincide ili) RASMOL is a sequence analysis tool
    • iv) If Zcal > Ztab, alternative hypothesis is
    • v) Yates’ correction reduces the deviation of the observed frequency from the expected
    • vi) Prosite is an example of genome database

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