BSc Biochemistry Sem VI 2018 19 Apr 2018-19 BIO CHEM IMMUNOLOGY AND PATHOPHYSIOLOGY Question Paper - Mumbai University | munotes

Questions asked in this paper

• 1) Please check if you have received the correct question paper

1. Q2 All the questions are compulsory. Choice is internal
2. Q3 Figures to the right indicate full marks
3. Q4 All questions carry equal marks Fill in the blanks (any three): 3
4. Q1 Immune complexes do not precipitate if is in excess
   • ii) The smaller complement component formed on activation and generally contributing to MAC formation is
   • iv) Most efficient antibody for complement activation is mainly
   • v) Test for use of steroids in athletes is based agglutination Answer in brief any one: 3
   • i) Explain the process of enhancing phagocytosis during complement activation
   • ii) Define and explain the terms affinity and avidity Write on any one: 6
5. Q1 Activation of complement by alternate pathway
   • ii) Agglutination inhibition reactions for diagnosis Answer any one: 8
6. Q1 Explain the use of agglutination reactions for clinical detection of any two Explain the activation of the complement system involving antibodies in the blanks (any three): 3
7. Q1 Transplant from a goat to a camel , is a type of
   • ii). Chromosome codes for Human Class IT MHC ili) is an APC
   • iv) I MHC is present on all cells
   • v) is an example of autoimmune disorder
8. Q2 B) Briefly explain any one: 3 marks
   • i) Positive selection
9. Q2 C) Attempt any one: 6 marks
10. Q1 With the aid of a neat diagram, describe the structure and function of a Elaborate on any one organ specific autoimmune disorder
11. Q2 D) Answer for any one: 8 marks
12. Q1 Discuss polymorphism as a means of creating diversity on MHC
    • ii) Elaborate on the immunological stages of graft rejection
13. Q3 A)_ Fill in the blanks (any three): 3 marks
14. Q1 In HIV, Protease enzyme is responsible for ‘ is more prevalent in people suffering from AIDS
    • iv) A structural component that is found in all viruses is
    • v) is the extracellular form of a virus
15. Q3 B) Explain any one giving the full form of the abbreviation: 3 marks
16. Q3 C) With the aid of a neat diagram explain the structure of any one: 6 marks
17. Q3 D) Answer in detail any one: 8 marks
18. Q1 Elaborate on the structure and replication of poliovirus
    • ii) Elaborate on therapy being used to manage AIDS
19. Q4 A) Fill in the blanks (any three): 3 marks
20. Q1 is also known as senescence
    • ii) During ageing protein levels are depressed is a potential cross linker
    • iv) Alzheimer's associated symptoms in the early stage resemble
    • v) is associated with low insulin levels
21. Q4 B) Answer in brief any one: 3 marks
    • i) What is Gerontology?
    • ii) State any two points of difference between Diabetes mellitus and Diabetes Write a short note on any one: 6
    • i) propagated to explain ageing
    • ii) Pathophysiology of Alzheimer’s disease
22. Q4 D) Attempt any one: 8 marks
23. Q1 Do you agree that the changes in enzymes as well as length of telomere contribute to ageing? Support your answer with valid reasons
    • ii) Explain - Diabetes mellitus is caused not only due to an endocrine disorder
24. Q5 A) Write brief note on any one: 4 marks
25. Q1 Ouchterlony reaction li) Effects of the complement system
26. Q5 B) Answer any one: 4 marks
27. Q1 Write briefly on dendritic cells
    • ii) Describe the types of grafts generally never rejected
28. Q5 C) Answer any one: 4 marks
29. Q1 Write a brief on symptoms of AIDS
    • ii) What reasons contribute to ineffectiveness of anti-influenza vaccine?
30. Q5 D) Attempt any one: 4 marks
31. Q1 Explain the role of free radicals in ageing li) Write a brief on Diabetes insipidus State true or false (any four): 4
    • i) Each antigen can bind to an through its epitope ili) All types of arthritis are autoimmune disorders
    • iv) an anaphylatoxin
32. Q5 The viral envelope is made of glycoproteins v1) virus has helical symmetry

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