BSc Sem VI 2022 2023 Apr 2023 BIOCHEMISTRY IV IMMUNOLOGY AND PATHOPHY SIOLOGY II Question Paper - Mumbai University | munotes

Questions asked in this paper

• Instructions to the candidates:- Please check that you have got the correct

1. Q1 All the questions are compulsory. Choice is internal
2. Q2 Figures to the right indicate full marks. All questions carry equal marks
3. Q3 From question Nos. 5, attempt any ONE question
4. Q1 Fillin the blanks 4 marks
5. Q1 Antiserum type of association is depicted between the antigen and the
   • ii) Agglutination reactions are as compared to precipitation ili) Complement components are to heat
   • iv) Coombs test is used to detect
6. Q1 B) Write a ANY ONE 4 marks
7. Q1 Blood typing
   • ii) Effects of complement activation Answer ANY TWO 12
8. Q1 Compare and contrast : Agglutination and Precipitation
   • ii) Justify: ELISA has diverse application
   • iii) Explain the formation of membrane attack complex through antigen
9. Q2 A) the blanks 4 marks
10. Q1 MHC Class is present on phagocytes li) is a type of APC ili) A graft between different species is termed __ graft Iv) is a Systemic autoimmune disease
11. Q2 B) Write a note on ANY ONE 4 marks
12. Q1 Self-restriction of T cells
    • ii) Types of grafts
13. Q2 C) Answer ANY TWO 12 marks
14. Q1 Compare and contrast : MHC Class —I and MHC Class -II
    • ii) Describe the autoimmune disorder and explain the immunological basis of the same
    • a) Multiple Sclerosis
    • b) Myasthenia gravis ili) Describe the sensitisation stage of graft rejection
15. Q3 A) Fill in the blanks: 4 marks
16. Q1 A positive strand RNA genome can function as the ili) enzyme is present in HIV
    • iv) Small pox vaccine was made using virus
17. Q3 B) Create a note on the structure of ANY ONE virus 4 marks
    • i) Polio Virus
18. Q3 C) Attempt any TWO 12 marks
19. Q1 Elaborate on the causes leading to AIDS. Add a note on the symptoms associated with the disease
    • ii) What are the advantages that a virus having a segmented genome has over the other viruses? Diagrammatically represent the structure of ili) Suggest to Hetal the various management modalities developed for
20. Q1 Cells stop dividing after a undergoing a fixed number of divisions. This is known as
    • ii) Insulin is secreted by the lil) is a disorder of defective growth hormone
    • iv) Thyroxine is also known as
21. Q4 B) State true or false giving valid scientific reasoning for ANY ONE 4 marks
22. Q1 Diabetes insipidus is not associated with insulin secretion
    • ii) Activity of telomerase is not affected in ageing
23. Q4 C) Attempt any TWO 12 marks
24. Q1 Describe disorders associated with hypersecretion of the following
    • ii) Discuss the molecular changes associated with ageing
    • iii) Compare and contrast : Alzheimer’s and Parkinson’s diseases
25. Q5 A) Define and explain: 8 marks
    • a) RIA
    • b) Complement system
    • c) Autoimmunity
    • d) Polymorphism
    • e) Reverse transcriptase
    • g) Tau protein
26. Q5 B) State True or False with justification 12 marks
27. Q1 More the titre, higher is the infection
    • ii) Cl is not involved in classical pathway of complement activation ili) Peptide binding cleft in MHC class is made of only alpha chain
    • iv) LDH is found to decrease with age
    • v) Chicken pox is caused by vaccinia virus
    • vi) HIV positive and AIDS are synonymous terms

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