BSc Sem VI 2022 2023 Apr 2023 BIOTECHNOLOGY PAPER I CELL BIOLOGY,MEDICAL BIOTECH & BIOSTAT Question Paper - Mumbai University | munotes

Questions asked in this paper

• 1. Attempt all questions

1. Q2 All questions carry equal marks
2. Q4 Use of log tables and non-programmable calculator is allowed
3. Q1 a. Define the following: (any three) 3 marks
4. Q4 Gap junctions
5. Q6 Second messengers
6. Q1 b. account of: (any two) 12 marks
7. Q1 General principles of cell communication
8. Q2 How the life span of a signalling molecule affects the signalling
9. Q3 Structure of GPCR and G proteins
10. Q4 Role of calcium as a second messenger
11. Q2 a. Name the following: (any three) 3 marks
12. Q1 Phase of the cell cycle in which DNA is replicated
13. Q2 The enzyme responsible for the phosphotidyl serine from the inner leaflet to outer leaflet of plasma membrane
14. Q3 Cells that do not divide in their life time
15. Q4 The enzyme which helps in detachment of an apoptopic cell from the
16. Q5 The membrane bound vesicles being released from a cell undergoing
17. Q6 A protein which regulates the cell cycle
18. Q2 b. Explain the following: (any two) 12 marks
19. Q1 What are checkpoints in a cell cycle? Give their significance
20. Q2 Explain the Intrinsic pathway of Apoptosis
21. Q3 What are Tumour Suppressor Genes? Give their role in the normal functioning of a cell
22. Q4 Compare the characteristics of a normal cell with a cancerous cell
23. Q3 a. Doas instructed: (any three) 3 marks
24. Q1 Give one example of antiviral drug
25. Q2 Fill in the blank - a polyene antifungal from Streptomyces is used to control candida
26. Q3 State true false — indiscriminate antimicrobial use results in the selection of resistant strains
27. Q4 Explain the term - Narrow spectrum antibiotic
28. Q5 Name the scientist who coined the term selective toxicity
29. Q6 Name one pharmacological activity of an antimicrobial agent Elaborate on the following questions: (any two) 12
30. Q1 Classification of antibacterial agents
31. Q2 Mode of action of tetracylins and chloramphenicol
32. Q3 Origin and transmission of drug resistance
33. Q4 Mechanism of action of quinolones and rifampin
34. Q4 a. three) 3 marks
35. Q1 Calculate mode: 2, 4, 6, 6, 6, 6,6, 6, 8 marks
36. Q2 Define- Median
37. Q3 State true or false: Histogram is a graph containing set of rectangles
38. Q4 If standard deviation is 6 what is the variance
39. Q5 Fill in the blank: In regression analysis, the variable whose value is unknown is variable
40. Q6 What is z-test?
41. Q4 b. Attempt the following questions: (any two) 12 marks
42. Q1 Calculate regression coefficients and b,x for the following data
43. Q2 What is correlation? Give types of correlation
44. Q3 Explain:
    • a. Null hypothesis and Alternative hypothesis
    • b. Type | and type 2 error
45. Q4 Solve: A machine is designed to produce insulating washers for electrical devices of average 0.50 cm. A random sample of 10 washers was found to have an average 0.55 cm with standard deviation of 0.05 cm. Test the significance of the deviation. (tg, = 2.262)
46. Q5 Write short notes on: (any three) 15 marks
    • b. Significance of Kd and binding energy of receptors Interphase and its stages
    • d. Biostatistics — Definition and its applications
    • f. Metronidazole — mode of action

Read from the scan above, so a character or two may differ. The scan is the original.