BSc Sem VI 2022 2023 Apr 2023 BIOCHEMISTRY III BIOSTATISTICS AND BIOINFORMATICS Question Paper - Mumbai University | munotes

Questions asked in this paper

• Instructions to the candidates:- Please check that you have got the correct question paper

1. Q1 questions are compulsory. Choice is internal
2. Q2 Figures to the right indicate full marks
3. Q3 All questions carry equal marks
4. Q5 Assume suitable information if necessary
5. Q6 Use of simple calculators is permitted
6. Q7 Use of statistical tables is permitted
7. Q8 Values for statistical problems: Match the following 4
   • (i)Positively skewed distribution (a) deviation with positive and negative values
   • (ii)Negatively skewed distribution | (b) Deviation with positive value Attempt ANY ONE 4
   • i) There are 60 students in a third-year biology class of which 25 are girls. The average weight of girls is 40 kg and that of boys is 53 kg. Find the mean weight in kg of the
   • ii) Create a note on Normal distribution
8. Q1 C) Answer ANY TWO 12 marks
   • i) Nisha is a research student and is interested in taking biostatistics for her studies Explain her scope and applications of biostatistics
   • ii) The following table gives the marks obtained in applied biotechnology by the students of a class of SY BSc. Find the median, and standard deviation
   • iii) Ina class in which all students practice at least one sport, 60% of the students play soccer or basketball, and 10% practice both. If there are 60% who do not play soccer, what is the probability that a student is chosen at random from the class: a) plays
9. Q2 A)_ the blanks 4 marks
10. Q1 an example of homology and similarity tool
    • ii) Microarray analysis is based on the principle ili) gives the exact order of the biopolymer as a linear sequence
    • iv) is the study of the pathway of evolution
11. Q2 B) Attempt ANY ONE 4 marks
12. Q1 Give account of proteomics and genomics
    • ii) With the help of a flow chart, explain the procedure for the cDNA microarray
13. Q2 C) Answer ANY TWO 12 marks
14. Q1 Compose a note on GenBank and PIR
    • ii) Elaborate on the classification of the databases citing suitable examples
    • iii) Enlisting various sequence analysis tools, give a comparative account of RASMOL and CLUSTAL-X giving their important characteristics and unique features
15. Q3 A) in the blanks: 4 marks
16. Q1 Type [error is depicted by the symbol li) Test to be conducted when n= 45 is test
    • iii) The standard error decreases as the sample size
    • iv) Ina one-tail test for the population mean, if the null hypothesis is not rejected when the alternative hypothesis is true, then error has been committed
17. Q3 B) Attempt ANY ONE 4 marks
18. Q1 Write a short note on null and alternative hypothesis
    • ii) Compare : One tailed and Two tailed tests
19. Q3 C) Attempt any TWO 12 marks
20. Q1 Describe the different types of errors possible during hypothesis testing
    • ii) a) Schematically represent the acceptance and rejection zone for Z test at 5% level of significance for a two tailed test
    • b) Mumbai Municipal Corporation is associated with two schools A and B in Andheri region and claims that the quality of education imparted at the two schools is at par The mean result of 100 students from School A was 72.4 with standard deviation 14.8, while the mean result of 200 students passing out from School B had a mean of 73.9 with standard deviation of 17.9. Is the claim of Mumbai Municipal Corporation that the two schools are at par, true?
    • iii) The mean of 2 sets of plots and their variability of yield are as below. Examine whether the difference in mean yields is significant Set 1 of plots | Set 2 of plots Number of plotsineachset
21. Q1 Reno Pharmacy examines the effect of high protein and high lipid diet to increase body weight, on 10 patients from paediatric ward and 10 patients from oncology ward Use of t test is recommended li) The degree of freedom fora t test is calculated as -2) ili) The synonym for t-test is test
    • iv) is a non-parametric rest
22. Q4 B) Compare ANY ONE 4 marks
23. Q1 Paired and unpaired T test
    • ii) T test and Chi Square test
24. Q4 Attempt any TWO 12 marks
    • i) 11 students were given a test on biostatistics. On analysing the performance they were given 2 months special coaching and then a second test was conducted. Marks obtained in test before and after coaching is depicted. Do the marks indicate that the special coaching has benefitted the students? Roll No of | 1 2 3 4 5 7 10 11
    • ii) The amount of fortified Vitamin D content in two brands of Milk- Brand A and B, was found to be as : Can we conclude that brand B has more Vitamin D fortification?
    • iii) In an anti-malaria campaign in a certain area, quinine was administered. The number of cases, wherein fever was observed is shown below: Suggest the association between quinine and fever
25. Q5 A) Define and explain: 8 marks
    • a) Interquartile range
    • b) Decile
    • e) Level of significance
    • f) Parametric test
    • g) Contingency table
    • h) Degree of freedom
26. Q5 B) State True or False with justification 12 marks
27. Q1 distribution, mean + S.D. covers almost 50% area under the curve
    • ii) P50 value is similar to that of median
    • iii) The phylogenetic tree depicts evolutionary relationships in the form of a Dendrogram
    • iv) If test statistic value is greater than the table value, null hypothesis is accepted
    • v) Mendel’s laws can be tested by the Chi square test
    • vi) in absence of any mention of level of significance , a = 0.1

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