BSc Sem VI 2014 2015 2015 Chemistry 2 Question Paper - Mumbai University | munotes

Questions asked in this paper

1. Q1 Write general stracture of Benzodiazepines. Give its structure activity What is drug absorption? Explain any factor affecting the absorption 3 marks
   • (4) Give the synthesis of Paludrine. 3
   • (ii) Discuss drug distribution to tissues of the body. 2 @& Give the synthesis of Ciproficxacin. 3
   • (ii) What are anthelmintics. its mode of action? 2 Give te is of p-[2'-(5-chloro 2- P @ Discuss any methods by which Tuberculosis is diagnosed. 3 @ What causes cancer? What is meant by Malignancy-? 2 4 Give the synthesis of 5- Fluorouracil from urea. 3 Explain the following drug delivery and its advantages. 2 of carbon nanotubes in the treatment of cancer. 1 Give the synthesis of p-Acetyl amino benzenesulphonyl
   • Q.P. Code : 14496
   • (d) Give a brief idea about the following- 5
   • (i) Pathogenicity of HIV
   • (ii) Use of Gold nano particles in the treatment of Alzheimer's disease. OR
   • (i) Give the synthesis of (+) Ethambutol. 3
   • (ii) Write the structure and chemical class of Diloxamide furoate. 2
2. Q3 (a) (i) How will you prepare Resorcinol from Benzene? 3 marks
   • (ii) Explain the dye fiber attachment due to Van der waal's force of 2
   • (a) Give preparation of the following 5
   • (i) 2-methylanthraquinone from Phthalic anhydride
   • (ii) 2-naphthol from Naphthalene Answer ANY TWO of the following
   • (b) What is nitration? Give one example of nitration: the role of conc. 3 Gi) Explain the term intermediates with examples: 2
   • (c) How will you prepare Naphthol ASG 3
   • (ii) Write a note on halogenation with example. 2
   • (d) (i) What is unit process? Explain sulpkonation with suitable example 3
   • (ii) Write a note on direct dyeing of cotton 2
   • (e) (i) Give synthesis of Benzanthrorie from Anthracene. 3
   • (ii) Write a note on mordant dyéing of cotton. 2
3. Q4 (a) Give the synthesis of from Aniline and write its uses. 5 marks
   • (a) How will you prepare Orange IV using Sulphanilic acid? 3
   • (ii) Discuss the harmful effects of Benzidine dyes on human health. 2 Answer ANY TWO of following
   • (b) How will Diamond Black F starting from N. W. acid? Give its uses 5
   • (ii) Write the structure of silk and give the classes of dyes applied to it
   • (d) How is Safranine T prepared from o-toluidine? Give its uses Write the synthesis of Eosine using Phthalic anhydride (ti) Write the harmful effects of textile dyes on human health
   • Q.P. Code : 14496 a In the by choosing the corr
   • (i) are obtained from
   • (ii) Structure of PAS jg
   • (1) (2) on 3
   • (iii) Nanoparticles are those particles which necessarily have
   • (1) all dimensions=150nm all dimensions between 1-100 nm
   • (3) all dimensions > 100 nm
   • (iv) Antibiotics must be effective is concentration
   • (v) combination of drugs is used in the treatinent of Tuberculosis
   • (b) Match the following 5
   • (i) Increase in activity (a) AIDS
   • (c) State whether are True or False. 5
   • i) Wi of CADD, activity of ligands binding with receptor can
   • (i) With the heip
   • (ii) PAS isthe drug used to treat tuberculosis
   • (iii) groups and other structural units responsible for phar macological action of a drug are called as pharmacophores, is caused by Entamoeba histolytica 2,4,5 - triamino - 6 hydroxypyrimidine is an intermediate used in the
   • d) he structure of following dyes. 5 State True or False > 5 Ionic forces results in covalent type of linkage between the dye and the
   • (ii) Primaries can directly be converted to dye
   • (iii) Polyester is hydrophobic fiber
   • (iv) Food colours have to be approved by the FDA
   • (v) Diazotization is carried out at high temperature
   • (f) Complete the following reaction and rewrite them: 5

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