B.Sc. (Biotechnology) Cell Regulation Developmental Biology and Cancer Biology Syllabus - Mumbai University 2026
This is the TY BSc Biotechnology syllabus under NEP 2020, in force from the academic year 2026-27. The University still examines the earlier Choice Based papers alongside it — her third-year office registers name that scheme — so check which scheme your exam form names before you revise.
Loading syllabus...
Syllabus for Cell Regulation Developmental Biology and Cancer Biology
Module I: Cell Cycle Regulation, Apoptosis and Cell Signalling (15
- 9 Lectures)
- Cell cycle and checkpoints: (5 lectures) ‒ Concept and phases of the cell cycle ‒ Prokaryotic cell cycle and Eukaryotic cell cycle ‒ Cyclins, cyclin-dependent kinases (CDKs), and CDK inhibitors ‒ Cell cycle checkpoints: G₁/S checkpoint, G₂/M checkpoint, spindle assembly checkpoint
- Apoptosis: (4 lectures) ‒ Definition, biological significance, and morphological features ‒ Intrinsic (mitochondrial) apoptotic pathway ‒ Extrinsic (death receptor-mediated) apoptotic pathway ‒ Apoptosis and necrosis
- Cell signalling (6 lectures) ‒ Autocrine, paracrine, endocrine, and juxtacrine signaling ‒ Signal transduction mechanisms and amplification Signalling pathways: eg. GPCRs, second messengers (cAMP, Ca²⁺, IP₃)
Module II: Developmental Biology and Cancer Biology (15 Lectures)
- Developmental Biology (8 lectures) ‒ Scope and significance of developmental biology; relevance to biotechnology, medicine, and regenerative biology : ‒ Cleavage patterns and blastula formation: regulation versus mosaic development and blastula organization ‒ Gastrulation: morphogenetic cell movements and germ layer formation ‒ Body axis formation and embryonic patterning: anterior–posterior, dorsal–ventral, and left–right axis specification: conceptual understanding ‒ Homeobox and Hox genes in body plan specification and segment identity ‒ Organogenesis and tissue differentiation: epithelial–mesenchymal interactions and lineage commitment.
- Cancer Biology (7 lectures) ‒ Introduction to cancer: definitions and classification ‒ Normal cell vs. cancerous cell ‒ Multistep nature of carcinogenesis ‒ Tumour suppressor genes (p53, RB) ‒ Cell cycle dysregulation in cancer and evasion of apoptosis by cancer cells ‒ Invasion and metastasis ‒ Overview of cancer therapeutics: chemotherapy, targeted therapy, immunotherapy
Textbooks
- 1 Alberts, B. et al. – Molecular Biology of the Cell, Garland Science, 4th Edition
- 2 Cooper, G.M. & Hausman, R.E. – The Cell: A Molecular Approach, 4th Edition
- 3 Gerald Karp;Cell and MolecularBiologyConcepts and Experiments; 6th edition
- 4 Wolpert, L. et al. – Principles of Development; 6th Edition
- 5 Gilbert, S.F. – Developmental Biology, Sinauer Associates, 7th Edition
- 6 Weinberg, R.A. – The Biology of Cancer, Garland Science,2nd Edition
- 1 Lodish, H. et al. – Molecular Cell Biology, W.H. Freeman; 6th Edition
- 2 Slack, J.M.W. – Essential Developmental Biology; 2nd edition
Reproduced from the University of Mumbai syllabus for B.Sc. (Biotechnology) under NEP 2020, in force from the academic year 2026-27. Wording is as printed in that syllabus. Module numbering is as printed there too.