B.Sc. (Biotechnology) Molecular Biology II Syllabus - Mumbai University 2026
This is the SY BSc Biotechnology syllabus under NEP 2020, in force from the academic year 2025-26. The University still examines the earlier Choice Based papers alongside it — her third-year office registers name that scheme — so check which scheme your exam form names before you revise.
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Syllabus for Molecular biology - II
Module I: Transcription
- Transcription in Prokaryotes:
- lectures)
- Components of prokaryotic transcription unit.
- Initiation of Transcription at Promoters - Role of promoter, consensus sequences.
- Action of RNA polymerase in initiation and elongation
- Elongation of an RNA Chain.
- Termination of an RNA Chain - Rho-dependent and Rho-independent termination.
- Transcription in Eukaryotes:
- lectures)
- Components of eukaryotic transcription unit.
- Eukaryotic RNA Polymerases - types and functions, Eukaryotic Promoters and Enhancers.
- Assembly of transcription initiation machinery.
- Structure and Production of Eukaryotic mRNAs.
- Eukaryotic mRNA processing, Spliceosomes.
- RNA editing.
Module II: Translation
- Nature of Genetic Code - Characteristics, ORF, Wobble Hypothesis.
- lectures)
- Role of different types of RNA in translation. (1 lecture) Charging of tRNA. (1 lecture)
- Translation in Prokaryotes and Eukaryotes - Process of Protein Synthesis (Initiation, Elongation, Translocation, Termination); Polyribosomes. (7
- lectures)
- Protein sorting - Signal hypothesis, effect of overlapping genes. (2 lectures)
- Post Translational Modifications. (2 lectures)
Text Books
- iGenetics- molecular approach - Peter Russell -3rd Edition Chapter 5 pg no. 81-101
- iGenetics- molecular approach - Peter Russell -3rd Edition Chapter 6 pg no. 102-123
- Cell and Molecular Biology, De Robertis, Lippincott Williams& Wilkins
- Karp's Cell and Molecular Biology: Concepts and Experiments—Karp – Wiley International
- Molecular Biology of the Cell, Bruce Alberts, Garland Science, Taylor & Francis group
- Molecular Cell Biology, Lodish, W.H.Freeman & Co Ltd
Reproduced from the University of Mumbai syllabus for B.Sc. (Biotechnology) under NEP 2020, in force from the academic year 2025-26. Wording is as printed in that syllabus. Module numbering is as printed there too.