MSc Biotechnology SEM II 2018 19 May 2018-19 BIOTECH IMMUNOLOGY Question Paper - Mumbai University | munotes

Questions asked in this paper

1. Q1 Answer the following questions (Any Two) 12 marks
   • a) Discuss systemic autoimmune diseases with any two suitable examples
   • b) “Induced animal models of autoimmune diseases have been proved to be useful to study autoimmune disorders.” Justify
   • c) Write a note on clinical manifestations of graft rejection
   • d) Explain immunodeficiency of myeloid lineage by two suitable examples
2. Q2 Attempt the following questions (Any Two) 12 marks
   • a) Diagrammatically explain gene targeting with cre/loxP system
   • b) Explain parenteral administration with two suitable examples
   • c) Discuss the procedure for producing transgenic mice
   • d) Write a note on generation of phage libraries containing antibody binding
3. Q3 Elaborate on the following (Any Two) 12 marks
   • a) In-Vitro cell imaging techniques
   • b) Reporter assays
   • c) Any two Apoptosis assays
   • d) Microarrays in immunology
4. Q4 Answer the following questions (Any Two) 12 marks
   • a) note on Psychological Modulation of immunity by Classical Describe the role of Glucocorticoids in PNI
   • c) Explain in detail the application of LAK and TIL in cancer immunotherapy
   • d) Describe the procedure for identifying genes encoding tumor-specific
5. Q5 Write short notes on (Any Three) 12 marks
   • a) Chimeric antibodies
   • b) Graves’s Disease
   • e) Energy demand and balance in PNI

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