MSc Chemistry (Organic and Analytical) SEM III CHEMISTRY ORGANIC CHEMISTRY SYNTHETIC ORGANIC CHEMISTRY I Question Paper - Mumbai University | munotes

Questions asked in this paper

• 2) Figures to the right indicate full marks

1. Q1 Attempt any two of the following: 8 marks
2. Q1 Complete the following reaction Name the reaction and explain its mechanism
   • ii) | Give one example each of the following
   • iii) Give the product, name and mechanism of the following reaction
   • iv) Complete the following reactions. Give the name of each of the reactions B Attempt any one of the following: 4
3. Q1 What are the components of the Darzen’s glycidic ester condensation? Write a suitable example of this reaction and explain its mechanism
   • ii) What are the characteristics of a click reaction? Give an example of the Huisgen
4. Q2 A Attempt any two of the following: 8 marks
5. Q1 Discuss with suitable example, intramolecular C-C bond formation using
   • ii) Define radicals and discuss the characteristics of radicals ili) Predict the product, name the reaction and suggest the mechanism Predict the product, name the reaction and suggest the mechanism B Attempt any one of the following: 4
6. Q1 Predict the product and suggest the mechanism
7. Q3 Bu,Sn-H ii) Discuss with example, intramolecular C-C bond formation using N-hydroxy
8. Q3 A Attempt any two of the following: 8 marks
9. Q1 How are the following compounds prepared via enamine?
   • ii) What are S-ylides? How are they prepared? Give two applications of S-ylides in ili) | How are alkenes prepared by coupling reaction between diazo compounds and ketones? Name the reaction involved
   • iv) Explain the generation of carbanions in nitro compounds and phosphonates and give one application of each in C-C bond formation B Attempt any one of the following: 4
10. Q1 What is Steven’s rearrangement? Illustrate with the mechanism and one
    • ii) Using phosphorus ylide, suggest synthesis of the following compound. Name the reaction involved and provide a mechanism for the same
11. Q4 A Attempt any two of the following: 8 marks
12. Q1 Complete the following reaction with correct stereochemistry and predict the
    • ii) Complete the following reaction. Give the name and mechanism of the reaction ili) | Complete the following reaction by identifying A, B, C, and D
    • iv) Give the following conversion via selenoxide B Attempt any one of the following: 4
13. Q1 Complete the following reaction and identify A, B, C and D Complete the following reaction by identifying W, X, Y and Z
14. Q5 Answer any four of the following: 12 marks
    • (a) multicomponent reaction is useful in the synthesis of dihydropyridines? What are the components in this reaction? Write the equation for a suitable
    • (b) With example explain the mechanism for the Strecker reaction
    • (c) Write the examples of persistent radical, electrophilic and nucleophilic radical Discuss the stability of following radicals and arrange it in increasing order of
    • (e) the reactivity of enamines and enolates
    • (f) | Write a brief note on Bestman Ohira reagent
    • (g) the following reactions by identifying A, B and C
    • (h) the following reaction by identifying A, B and C

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