TYBSc Analytical Chemistry 3 Units Syllabus Mumbai University by munotes
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T.Y.B.Sc. CHEMISTRY (3 UNITS)
Choice Based Credit System
SEMESTER V
ANALYTICAL CHEMISTRY
COURSE CODE: USCH504 CREDITS: 01 LECTURES: 30
UNIT I :INTRODUCTION TO QUALITY CONCEPTS,CHEMICAL
CALCULATIONS AND SAMPLING (3 & 6 UNITS)
1.1 Quality in Analytical Chemistry 05 L
1.1.1 Concepts of Quality, Quality C ontrol and Quality Assurance
1.1.2 Importance of Quality concepts in Industry
1.1.3 Chemical Standards and Certified Reference Materials; Importance
in chemical analysis
Quality of material: Various grades of laboratory reagents
1.2 Chemical Calculations (Numerical s and word problems are expected) 04 L
1.2.1 Inter conversion of various concentration units.
(Conversion of concentration from one unit to another unit with
example s)
1.2.2 Percent composition of elements in chemical compounds
1.3 Sampling 06 L
1.3.1 Purpose, significance and difficulties encountered in sampling
1.3.2 Sampling of solids: Sample size – bulk ratio, size to weight ratio,
multistage and sequential sampling, size reduction methods,
sampling of compact solids, equipments and methods of sampling
of compact solids, sampling of particulate solids, methods and
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equipments used for sampling of particulate solids .
1.3.3 Sampling of liquids: Homogeneous and heterogeneous, Static and
flowing liquids .
1.3.4 Sampling of gases: Ambient and stack sampling: Apparatus and
methods for sampling of gases .
1.3.5 Collection, preservation and dissolution of the sample .
UNIT II : CLASSICAL METHODS OF ANALYSIS (TITRIMETRY)
2.1 Redox Titrations (Numerical and word Problems are e xpected) 08 L
2.1.1 Introduction
2.1.2 Construction of the titration curves and calculation of E system in
aqueous medium in case of :
(1) One electron system
(2) Multielectron system
2.1.3 Theory of redox indicators, Criteria for selection of an indicator
Use of diphenyl amine and ferroin as redox indicators
2.2 Complexometric Titrations 07 L
2.2.1 Introduction, construction of titration curve
2.2.2 Use of EDTA as titrant and its standardisation, absolute and
conditional formation constants of metal EDTA complexes,
Selectivity of EDTA as a titrant.
Factors enhancing selectivity with examples .
Advantages and limitations of EDTA as a titrant .
2.2.3 Types of EDTA titrations.
2.2.4 Metallochromic indicators, theory, examples and applications
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REFERENCES
1. 3000 solved problems in Chemistry, David E.
Goldberg,PhD.,Schaums Outline Unit/s: (1.2)
2. A guide to Quality in Analytical Chemistry: An aid to
accreditation, CITAC and EURACHEM, (2002), Unit/s (1.1)
3. A premier sampling solids, liquids and gases, Smith P atricia
I, American statistical association and the society for
industrial and applied mathematics, (2001) Unit/s (1.3)
4. Analytical Chemistry Skoog, West ,Holler,7th Edition: Unit/s (2.1)
5. Handbook of quality assurance for the analytical chemistry
laboratory, 2ndEdn., James P. DuxVanNostr and Reinhold,
1990 Unit/s (1.1)
6. Quality con trol and Quality assurance in An alytical
Chemical Laboratory, Piotr Konieczka and Jacek
Namiesnik, CRC press (2018) Unit/s (1.1)
7. Quality in the Analytical Chemistry Laboratory, Elizabeth
Prichard, Neil T. Crosby, Florence Elizabeth Prichard, John
Wiley and Sons, 1995 Unit/s (1.1)
PRACTICALS
SEMESTER V
ANALYTICAL CHEMISTRY
COURSE CODE: USCHP15 CREDITS: 01
1. Estimation of magnesium content in Talcum powder by complexometry, using
standardized solution of EDTA
2. Determ ination of COD of water sample.
3. To determine potassium content of a Fertilizer by Flame Photometry (Calibration curve
method).
Note: Calculation of percent error is expected for all the
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experiments.
REFERENCES
1. Vogel’s Textbook of Quantitative Chemical Analysis, 5thEdn., G. H. Jeffery, J Bassett, J
Memdham and R C Denney, ELBS with Longmann (1989).
2. Vogel's Textbook of Quantitative Chemical analysis, Sixth edition, J.Mendham et.al
SEMESTER VI
ANALYTICAL CHEMISTRY
COURSE CODE: USCH604 CREDITS: 01 LECTURES: 30
UNIT I : ELECTRO ANALYTICAL TECHNIQUES
1.1 Polarography (Numerical and word problems are expected) 11L
1.1.1 Difference between potentiometry and voltammetry, Polarizable and
non-polarizable electrodes
1.1.2 Basic principle of polarography
H shaped polarographic cell, DME (construction, working,
advantages and limitations)
1.1.3 DC polarogram: Terms involved - Residual current, Diffusion
current, Limiting current, Half -Wave Potential
Role and selection of supporting electrolyte , Interference of oxygen
and its removal , polarographic Maxima and Maxima Suppressors
Qualitative aspects of Polarography: Half wave pot ential E 1/2,
Factors affecting E 1/2
Quantitative aspects of polarography: Ilkovic equations: various
terms involved in it (No derivation)
1.1.4 Quantification
1) Wave height – Concentration plots ( working
plots/calibration)
2) Internal standard (pilot ion) method
3) Standard addition method
1.1.5 Applications advantages and limitations
1.2 Amperometric Titrations 04L
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1.2.1 Principle, Rotating Platinum Electrode(Construction, advantages
and limitations)
1.2.2 Titration curves with example
1.2.3 Advantages and limitations
UNIT II : METHODS OF SEPARATION - II (3 & 6 UNITS)
2.1 Gas Chromatography (Numerical and word p roblems are e xpected ) 09 L
2.1.1 Introduction, Principle , Theory and terms involved
2.1.2 Instrumentation: Block diagram and components, types of c olumns ,
stationary phases in GSC and GLC, Detectors: TCD, FID, ECD
2.1.3 Qualitative, Quantitative analysis and applications
2.1.4 Comparison between GSC and GLC
2.2 Ion Exchange Chromatography 06 L
2.2.1 Introduction, Principle.
2.2.2 Types of Ion Exchangers , Ideal properties of resin
2.2.3 Ion Exchange equilibria and mechanism, selectivity coefficient and
separation factor
Factors affecting separation of ions
2.2.4 Ion exchange capacity and its determination for cation and anion
exchangers.
2.2.5 Applications of Ion Exchange Chromatography with reference to
Preparation of demineralised water, Separation of amino acids
REFERENCES
1. Analytical Chemistry, Gary.D Christan, 5th edition Unit/s (2.1,2.2 )
2. Analytical chemistry, R. K. Dave. Unit/s (2.1,2.2 )
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3. Chemical methods of separation, J A Dean, Van Nostrand
Reinhold, 1969 Unit/s (2.1,2.2 )
4. Egyankosh.ac.in/bitstream/123456789/43329/1/Unit -8 Unit/s ( 1.1,1.2,1 .3)
5. Fundamentals of Analytical Chemistry, D .A. Skoog and D. M.
West and F. J. Holler Holt., Saunders 6th Edition (1992) Unit/s (2.1,2.2 )
6. Instrumental methods Of Analysis, by Willard Merritt Dean,
7thEdition, CBS Publisher and distribution Pvt Ltd Unit/s (1.1,1.2,1.3)
7. Introduction to Polarography and Allied Techniques, By Kamala
Zutshi, New Age International, 2006. Unit/s (1.1,1.2,1 .3)
8. Principles of Polarography by Jaroslav Heyrovský , Jaroslav
Kůta, 1st Edition, Academic Press, eBook ISBN: 9781 48326478 Unit/s (1.1,1.2,1 .3)
9. Solvent extraction and ion exchange, J Marcus and A. S. Kertes
Wiley INC 1969 Unit/s (2.1,2.2,)
PRACTICALS
SEMESTER VI
ANALYTICAL CHEMISTRY
COURSE CODE: USCHP16 CREDITS: 01
1 Estimation of Chromium in water sample spectrophotometrically by using Diphenyl
carbazide.
2 Estimation o Mg+2 & Zn+2 by anion exchange resin.
3. Estimation of acetic acid in Vinegar sample by using Quinhydrone electrode
potentiometrically.
Note: Calculation of percent error is expected for all the
experiments.
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REFERENCES
1. Vogel’s Textbook of Quantitative Chemical Analysis, 5thEdn., G. H. Jeffery, J Bassett, J
Memdham and R C Denney, ELBS with Longmann (1989).
2. Vogel's Textbook of Quantitative Chemical analysis, Sixth edition, J.Mendham et.al
3. The chemical analysis of food and food products III edition Morris Jacob
4. The chemical analysis of food by David Pearson and Henry Edward