TE Biomedical Engg Sem V and Sem VI1_1 Syllabus Mumbai University

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Copy to : -
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(AAMS),
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Department (CAD),
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Migration Department (AEM),
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7. The Deputy Registrar, (Special Cell),
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(FAD) (VAD), Record Section,
9. The Director, Institute of Distance and Open Learni ng (IDOL Admin),
Vidyanagari,
They are requested to treat this as action taken report on the concerned
resolution adopted by the Academic Council referred to in the above circular
and that on separate Action Taken Report will be sent in this connection.

1. P.A to Hon’ble Vice -Chancellor,
2. P.A Pro -Vice-Chancellor,
3. P.A to Registrar,
4. All Deans of all Faculties,
5. P.A to Finance & Account Officers, (F.& A.O),
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9. The Director, Dept. of Information and Communication Technology
(DICT) (CCF & UCC), Vidyanagari,
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12. All Deputy Registrar, Examination House,
13. The Deputy Registrars, Finance & Accounts Section,
14. The Assistant Registrar, Administrative sub -Campus Thane,
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for information.

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AC - 29/06/2021
Item No. - 6.1

UNIVERSITY OF MUMBAI



Bachelor of Engineering
in
Biomedical Engineering
Third Year with Effect from AY 2021 -22
(REV - 2019 ‘C’ Scheme) from Academic Year 2019 – 20
Under
FACULTY OF SCIENCE &
TECHNOLOGY


(As per AICTE guidelines with effect from the academic
year 2019 –2020)

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University of Mumbai, Biomedical Engineering, Rev 202 1-22



















Date


Dr. S. K. Ukarande Dr Anuradha Muzumdar
Associate Dean Dean
Faculty of Science and Technology Faculty of Science and Technology
University of Mumbai University of Mumbai Sr. No. Heading Particulars
1 Title of the Course Thir d Year B.E. Biomedical Engineering
2 Eligibility for Admission
After Passing Second Year Engineering as per the
Ordinance 0.624 3
3 Passing Marks 40%
4 Ordinances /
Regulations (if any) Ordinance 0.624 3
5 No. of Years / Semesters 8 semesters
6 Level Under Graduation
7 Pattern Semester
8 Status Revised
9 To be implemented from
Academic Year With effect from Academic Year: 202 1-2022



















































































AC:



Item No.:







Syllabus for Approval

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University of Mumbai, Biomedical Engineering, Rev 202 1-22 Preamble
To meet the challenge of ensuring excellence in engineering education, the issue of quality needs to be
addressed, debated and taken forward in a systematic manner. Accreditation is the principal means of
quality assurance in higher education. The major em phasis of accreditation process is to measure the
outcomes of the program that is being accredited. In line with this Faculty of Science and Technology (in
particular Engineering)of University of Mumbai has taken a lead in incorporating philosophy of outco me
based education in the process of curriculum development.
Faculty resolved that course objectives and course outcomes are to be clearly defined for each course, so
that all faculty members in affiliated institutes understand the depth and approach of co urse to be taught,
which will enhance learner’s learning process. Choice based Credit and grading system enables a much -
required shift in focus from teacher -centric to learner -centric education since the workload estimated is
based on the investment of tim e in learning and not in teaching. It also focuses on continuous evaluation
which will enhance the quality of education. Credit assignment for courses is based on 15 weeks teaching
learning process, however content of courses is to be taught in 12 -13 weeks and remaining 2 -3 weeks to be
utilized for revision, guest lectures, coverage of content beyond syllabus etc.
There was a concern that the earlier revised curriculum more focused on providing information and
knowledge across various domains of the said pr ogram, which led to heavily loading of students in terms
of direct contact hours. In this regard, faculty of science and technology resolved that to minimize the burden of
contact hours, total credits of entire program will be of 170, wherein focus is not only on providing knowledge but
also on building skills, attitude and self learning. Therefore in the present curriculum skill based laboratories and mini
projects are made mandatory across all disciplines of engineering in second and third year of program s, which will
definitely facilitate self learning of students. The overall credits and approach of curriculum proposed in the present
revision is in line with AICTE model curriculum.
The present curriculum will be implemented for Second Year of Engineering from the academic year 2020 -
21. Subsequently this will be carried forward for Third Year and Final Year Engineering in the academic
years 2021 -22, 2022 -23, respectively.
Dr. S. K. Ukarande
Associate Dean
Faculty of Science and Technology
Member, Academic Council, RRC in Engineering
University of Mumbai

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University of Mumbai, Biomedical Engineering, Rev 202 1-22 Incorporation and implementation of Online Contents from
NPTEL/ Swayam Platform

The curriculum revision is mainly focused on knowledge component, skill based activities and project
based activities. Self learning opportunities are provided to learners. In the revision process this time in
particular Revised syllabus of ‘C ‘ scheme wherever possible additional resource links of platforms such
as NPTEL, Swayam a re appropriately provided. In an earlier revision of curriculum in the year 2012 and
2016 in Revised scheme ‘A' and ‘B' respectively, efforts were made to use online contents more
appropriately as additional learning materials to enhance learning of studen ts.
In the current revision based on the recommendation of AICTE model curriculum overall credits are
reduced to 171, to provide opportunity of self learning to learner. Learners are now getting sufficient time
for self learning either through online cou rses or additional projects for enhancing their knowledge and
skill sets.
The Principals/ HoD’s/ Faculties of all the institute are required to motivate and encourage learners to use
additional online resources available on platforms such as NPTEL/ Swayam. Learners can be advised to
take up online courses, on successful completion they are required to submit certification for the same. This
will definitely help learners to facilitate their enhanced learning based on their interest.

Dr. S. K. Ukarande
Asso ciate Dean
Faculty of Science and Technology
Member, Academic Council , RRC in Engineering
University of Mumbai

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University of Mumbai, Biomedical Engineering, Rev 202 1-22 Preface By BoS
Engineering is an innovative field, the origin of ideas leading to everything from automobile to aerospace,
skyscrapers to sonar. Biomedical Engineering focuses on the advances that improve human health and
health care at all levels . Biomedical engineering is an interdisciplinary field with application of the
principles of Basic Sciences, Mathematics, Engineering fundamentals and Biology for problem -solving.
The curriculum is designed to meet the challenges by include new age courses on Machine Learning,
Artificial Intelligence , Data Analytics and other emerging technologies , dismantl ing the walls between
engineering and scientific disciplines. The key to generat e a new paradigm shift for careers in Biomedical
Engineering for the next generation of talented minds lies in imparting high-quality education in
Engineering .
Every course in the curriculum lists the course objectives and course outcomes for the learners to understand
the skills that the learner will acq uire after completing that course. Program outcomes are the skills and
knowledge that a student will acquire during the course of four years of this engineering program. In line
with this , Faculty of Technology of University of Mumbai has taken a lead in incorporating the philosophy
of outcome based education in the process of curriculum development.
As the Chairman, Board of Studies in Biomedical Engineering of the University of Mumbai, I am happy to
state here that, the Program Educational Objectives for undergraduate program were thoughtfully framed
by faculty members from different affiliated institutes of the university. They are Heads of Departments
and senior representatives from the Department of Biomedical Engineering.
The Program Educational Objectives for the undergraduate program in Biomedical engineering are listed
below;
1. To prepare the learner with a sound foundation in the Human Physiology, Mathematic s, Electronics,
Computer Programming and engineering fundamentals .

2. To motivate the learner for self-learning , logical & analytical thinking and use of modern tools for solving
real life problems .

3. To impart technical knowledge, competency skills, professional and ethical attitude, good leadership
qualities to contribute in the field of healthcare.

4. To prepare the Learner for a successful career in healthcare industry such as sales & marketing, research
& development, hospital administration and also to venture into higher education and entrepreneurship.


Board of Studies in Biomedical Engineering
Dr. Manali J. Godse : Chairman
Dr. Prem C . Pandey : Member
Dr. Mita Bhowmick : Member
Dr. Mrunal R. Rane : Member
Dr. Vaibhavi A. Sonetha : Member

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University of Mumbai, Biomedical Engineering, Rev 202 1-22 Program Structure for Third Year Engineering
Semester V & VI
UNIVERSITY OF MUMBAI
(With Effect from 20 21-2022)
Semester V
Course
Code Course Name Teaching Scheme
(Contact Hours) Credits Assigned
Theory Pract. Theory Pract . Total
BMC501 Biomedical
Instrumentation – I 3 -- 3 -- 3
BMC5 02 Digital Signal
Processing 3 -- 3 3
BMC503 Microcontrollers and
Embedded Systems 4 -- 4 -- 4
BMC504 Medical Imaging – II 3 -- 3 -- 3
BMDO501X Department Optional
Course – 1 3 -- 3 -- 3
BML5 01 Biomedical
Instrumentation – I
Laboratory -- 2 -- 1 1
BML5 02 Digital Signal
Processing Laboratory -- 2 -- 1 1
BML5 03 Microcontrollers and
Embedded Systems
Laboratory -- 2 -- 1 1
BML504 Professional
Communication and
Ethics – II -- 2*+2 -- 2 2
BMM501 Mini Project – 2 A -- 4$ -- 2 2
Total 16 14 16 07 23
Course
Code Course Name Examination Scheme
Theory
Term
Work Prac
/oral Total Internal Assessment End
Sem
Exam Exam.
Duration
(in Hrs) Test
1 Test
2 Avg
BMC501 Biomedical
Instrumentation – I 20 20 20 80 3 -- -- 100
BMC5 02 Digital Signal
Processing 20 20 20 80 3 -- -- 100
BMC503 Microcontrollers and
Embedded Systems 20 20 20 80 3 -- -- 100
BMC504 Medical Imaging – II 20 20 20 80 3 -- -- 100
BMDO501X Department Optional
Course – 1 20 20 20 80 3 -- -- 100
BML5 01 Biomedical
Instrumentation – I
Laboratory -- -- -- -- -- 25 25 50
BML5 02 Digital Signal
Processing Laboratory -- -- -- -- -- 25 25 50

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University of Mumbai, Biomedical Engineering, Rev 202 1-22 BML5 03 Microcontrollers and
Embedded Systems
Laboratory -- -- -- -- -- 25 25 50
BML504 Professional
Communication and
Ethics -- -- -- -- -- 25 25 50
BMM501 Mini Project – 2 A -- -- -- -- -- 25 -- 25
Total -- -- 100 400 -- 125 100 725
* Theory class to be conducted for full class
$ indicates wor k load of Learner (Not Faculty), for Mini Project - 2 A
Faculty Load :1 hour per week per 4 mini project groups.

Sem. V: Department Optional Course – 1
BMDO5011 : Principles of Communication Engineering
BMDO5012: Very Large Scale Integration
BMDO5013: Tissue Engineering

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University of Mumbai, Biomedical Engineering, Rev 202 1-22 Semester VI
Course
Code Course Name Teaching Scheme
(Contact Hours) Credits Assigned
Theory Pract. /Tut. Theory Pract . Total
BMC601 Biomedical
Instrumentation – II 3 -- 3 -- 3
BMC6 02 Biomedical Digital
Image Processing 3 -- 3 3
BMC603 Data Analysis in
Healthcare 3 -- 3 -- 3
BMC604 Biomechanics,
Prosthetics and
Orthotics 3 1 3 -- 4
BMDO601X Department Optional
Course – 2 3 -- 3 -- 3
BML6 01 Biomedical
Instrumentation – II
Laboratory -- 2 -- 1 1
BML6 02 Biomedical Digital
Image Processing
Laboratory -- 2 -- 1 1
BML6 03 Data Analysis in
Healthcare Laboratory -- 2 -- 1 1
BML604 Patient -care
Automation
Laboratory -- 4 -- 2 2
BMM601 Mini Project – 2 B -- 4$ -- 2 2
Total 15 15 15 07 23
Course
Code Course Name Examination Scheme
Theory
Term
Work Prac
/oral Total Internal Assessment End
Sem
Exam Exam.
Duration
(in Hrs) Test
1 Test
2 Avg
BMC601 Biomedical
Instrumentation - II 20 20 20 80 3 -- -- 100
BMC6 02 Biomedical Digital
Image Processing 20 20 20 80 3 -- -- 100
BMC603 Data Analysis in
Healthcare 20 20 20 80 3 -- -- 100
BMC604 Biomechanics,
Prosthetics and
Orthotics 20 20 20 80 3 25 -- 125
BMDO601X Department Optional
Course – 2 20 20 20 80 3 -- -- 100
BML6 01 Biomedical
Instrumentation – II
Laboratory -- -- -- -- -- 25 25 50
BML6 02 Biomedical Digital
Image Processing
Laboratory -- -- -- -- -- 25 25 50

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University of Mumbai, Biomedical Engineering, Rev 202 1-22 BML6 03 Data Analysis in
Healthcare Lab oratory -- -- -- -- -- 25 -- 25
BML604 Patient -care
Automation
Laboratory -- -- -- -- -- 25 25 50
BMM601 Mini Project – 2 B -- -- -- -- -- 25 25 50
Total -- -- 100 400 -- 150 100 750
$ indicates wor k load of Learner (Not Faculty), for Mini Project - 2 B
Faculty Load :1 hour per week per 4 mini project groups.

Sem. V I: Department Optional Course – 2
BMDO 6011: Nuclear Medicine
BMDO6012: Advanced Embedded Systems
BMDO6013: Telemedicine

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University of Mumbai, Biomedical Engineering, Rev 202 1-22






Semester – V

Course
Code Course Name Teaching scheme Credit assigned
BMC501 Biomedical
Instrumentation - I
(Abbreviated as
BMI -I) Theory Pract. Tut. Theory Pract. Tut. Total
03 -- -- 03 -- -- 03

Course
Code Course Name Examination Scheme
Theory
Term
work Pract Oral Pract. /
Oral Total Internal Assessment End
sem Dura
tion
(hrs) Test
1 Test
2 Avg.
BMC
501 Biomedical
Instrumentation - I
(BMI -I) 20 20 20 80 03 -- -- -- -- 100

Course Code Course Name Credits
BMC501 Biomedical Instrumentation - I 03
Course O bjective • To understand the basic principles and working of diagnostic and therapeutic
equipment.
• To develop skills enabling Biomedical Engineers to serve the health care industry
• To develop core competency and skill in the field of Biomedical Engineering, to
desig n and develop new health care systems.
Course Outcome Learner will be able to …
• Explain the principles of various analytical instruments used in hospital and
laboratories.
• Demonstrate knowledge about various blood cell counting systems and blood gas
analyzers.
• Demonstrate knowledge about various automated drug delivery systems.
• Explain the basics of pulmonary function analyzer, ventilators, and demonstrate
the use of ventilation therapy and anesthesia machine.
• Explain the basic principle and working o f hemodialysis machine.

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University of Mumbai, Biomedical Engineering, Rev 202 1-22



Module Contents Hours

1. Basic principle, working and technical specifications of Analytical
Instruments
1. Colorimeter
2. Spectrophotometer
3. Auto Analyzer
4. Principles of Electrophoresis apparatus
5. Principles of Chromatography
6. ELISA concepts (direct and indirect), reader & washer.
10
2. Basic principle, working and technical specifications of
Blood cell counter (Coulter and Pico -scale)
Blood Gas Analyzer 04

3. Automated drug delivery systems
Infusion pumps, components of drug infusion systems, syringe and peristaltic
pumps.
04
4. Basic principle and working of Pulmonary Function Analyzer
Respiration measurement technique: lung volume and capacities, spirometry,
nitrogen washout, helium dilution, 06
5. Basic principle and working of Ventilators
Artificial ventilation, ventilator terms and its types, modes of ventilators,
classification of ventilators, pressure volume flow and time diagrams.
microprocessor controlled ventilator
Basic principle and working of Anesthesia Machine
Need for anesthesia, anesthesia machine: gas supply, flow and delivery
system vapor delivery and humidification and patient breathing capnography. 10
6. Basic principle, working and technical specifications of Hemodialysis
machine
Basic principle of dialysis , different types of dialyzer membrane s, portable
dialysers and various monitoring circuits.
05

Assessment :
Internal assessment consists of two tests out of which; one should be compulsory class test (on minimum 02
modules) and the other is either a class test or assignment on live problems or course project.

Books Recommended :
Text books:
1. Handbook of Biomedical Instrumentation (Third edition) : R S. Khandpur. (PH Pub)
2. Medical Instrumentation, Application and Design: J G. Webster. (John Wiley)
3. Biomedical Instrumentation and measurements : Leislie Cromwell, Fred J. Weibell, Enrich A.
Pfeiffer. (PHI Pub)

Reference books:

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University of Mumbai, Biomedical Engineering, Rev 202 1-22 1. Introduction to Biomedical Equipment Technology: Carr –Brown. (PH Pub)
2. Encyclopedia of Medical Devices and Instrumentation: J G. Webster. Vol I - IV (PH Pub)
3. Various Instruments Manuals.
4. Various internet websites.

Theory Examinatio n:
1. Question paper will comprise of total 06 questions, each carrying 20 marks.
2. Total 04 questions need to be solved.
3. Question No: 01 will be compulsory and based on entire syllabus wherein sub -questions of
marks will be asked.
4. Remaini ng questions will be randomly selected from all the modules.

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University of Mumbai, Biomedical Engineering, Rev 202 1-22 Sub Code Subject
Name Teaching Scheme Credits Assigned
Theory Pract. Tut Theory Pract. Tut Total
BMC502 Digital
Signal
Processing
(abbreviate
d as DSP) 3 -- - 3 -- -- 3

Sub Code Subject
Name Examination scheme
Theory Marks
Exam
Duration
(in hrs) Term
Work Prac/
Oral Total Internal Assessment End
Sem
exam Test 1 Test 2 Avg.
BMC502 Digital
Signal
Processing
(abbreviate
d as DSP) 20 20 20 80 3 --- --- 100


Course Code Course Name Credits
BMC502 Digital Signal Processing 03
Course
Objectives • To build a strong base in signal and image processing through algorithm
development.
• To develop competency in logical thinking, computer programming and
knowledge application.
• To train and motivate for higher education and research in order to make
contribution to state of the art health care for all.
Course
Outcomes Learner will be able to…
• Understand the fundamental techniques and applications in digital processing of
bio-signals.
• Understand circular and linear convolution and their implementation using Z -
transform and DFT.
• Understand and implement efficient computational techniques like FFT.
• Design FIR and IIR filters by different methods.


Module Contents Hours
1. Basic elements of D igital Signal Processing , concepts of frequency in analog and
digital signals, sampling theorem, discrete time signals and systems their properties,
Z-transform and properties, Linear & circular convolution, Correlation, DTFT . 08
2. Introduction to DFT, Properties of DFT, DIT and DIF , FFT algorithms, use of FFT
in linear filtering, discrete cosine transforms . 08
3. Review of design of analog Butterworth and Chebyshev filters, frequency
transformation in analog domain, design of IIR digital filters using impulse
invariance meth od, design of digital filters using bilinear transformation . 06

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University of Mumbai, Biomedical Engineering, Rev 202 1-22 4. Structure of FIR filters, linear phase filters, filter design using window technique,
frequency sampling techniques, finite word length effects in digital filters,
realisation of FIR & IIR filters, direct, cascade and parallel forms . 06
5. Introduction to digital signal processors, architecture, features, addressing formats,
functional mode, introduction to commercial processors, applications . 03
6. Preliminaries, biomedical signals (ECG, EMG, EEG) origin & dynamics, statistical
preliminaries, time domain filtering ( synchronized averaging, moving average),
time domain filtering ( moving average filter to integration -derivative based
operator), Frequency domain filtering ( notch Filter), optimal filtering: Weiner filter,
adaptive filtering, selecting appropriate filter 08

Assessment:
Internal assessment consists of two tests out of which; one should be compulsory class test (on minimum 02
modules) and the other is either a class test or assignment on live problems or course project.

Text books:
1. Digital signal processing Principles Algorithms and Application – Proakis &Manolakis – Third edition
PHI
2. Digital Signal Processing – Sanjit K. Mithra Tata Mc -graw Hill
3. Digital Signal Processing – S. Salivahanan, C. Gnanapriya, Tata McGraw Hill
Reference Books:
1. Digital signal processing – A.V. Oppenheim and R.W. Schafer - PHI
2. Understanding Digital Signal Processing – Richard G. Lyons - Pearson Publication
3. Biomedical Digital Signal Processing -- Willis J. Tompkins -- EEE, PHI, 2004
4. R M Rangayyan “Biomedica l Signal Analysis: A case Based Approach”, IEEE Press, John Wiley
& Sons. Inc, 2002

Theory Examination:
1. Question paper will comprise of 6 questions, each carrying 20 marks.
2. Total four questions need to be solved.
3. Q.1 will be compulsory, based on entire syllabus wherein sub questions of 2 to 5 marks will be asked.
4. Remaining question s will be randomly selected from all

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University of Mumbai, Biomedical Engineering, Rev 202 1-22 Course
Code Course Name Teaching scheme Credit assigned
BMC503 Microcontrollers
and Embedded
Systems
(Abbreviated as
MES) Theory Pract. Tut. Theory Pract. Tut. Total
04 -- -- 04 -- -- 04

Course
Code Course Name Examination Scheme
Theory Term
work Pract./O
ral Total Internal Assessment End
sem Duration
(hrs) Test 1 Test 2 Avg.
BMC503 Microcontrollers
and Embedded
Systems
(Abbreviated as
MES) 20 20 20 80 03 -- -- 100


Course Code Course Name Credits
BMC50 3 Microcontrollers and Embedded Systems 04
Course
Objectives • To provide the knowledge about the 8051 microcontroller architecture and
programming so that the learners can apply the this knowledge to design
microcontroller -based application
• To make learners aware of the basics of embedded systems and real time
operat ing system



Course
Outcomes Learner will be able to …
• Explain the fundamentals of embedded systems
• Apply the knowledge of 8051 Microcontroller architecture
• Apply the knowledge of 8051programming in assembly and C language
• Design and analyse 8051 interfacing with external memory, input/output
devices and PC
• Apply the concept of serial communication protocols
• Explain the concept of Real Time Operating Systems ( RTOS)

Module Contents Hours
1. Embedded systems : Definition, characteristics, constraints; processor embedded
into a system; embedded hardware units and devices in a system; embedded
software in a system; examples of embedded systems; design process in embedded
system; classification of embedded systems. 04

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University of Mumbai, Biomedical Engineering, Rev 202 1-22 2. 8051 Microcontroller Architecture : Introduction: Von Neumann and Harvard
architecture, CISC and RISC architecture , comparison of microprocessor and
microcontrollers; 8051 hardware block diagram, pin diagram, CPU timing and
machine cycles; 8051 programmer model, SFRs and PSW; 8051 Memory
organization , parallel I/O ports, integrated peripherals such as timers/counters,
serial port, interrupt structure; 8051 Power saving modes. 12
3. 8051 Microcontroller Programming: 8051 assembly language programming
process, programming tools; 8051 assembly language: addressing modes,
instruction set; assembly language programing and embedded C programing. 12
4. 8051 Microcontroller Interfacing : 8051 interfacing (and related programs) with -
external memory, keypad, LED, LCD, ADC and sensors, DAC, relays and d.c.
motors, stepper motor; Interfacing 8051 with pc using RS232. 12
5. Serial Communication Protocols: Operation of serial port, programming for
asynchronous serial communication; Serial communication using the ‘I2C’, SPI;
Introduction to USB & CAN bus. 06
6. Real Time Operating Systems (RTOS): Introduction to RTOS concept, RTOS
functions, Systimer, process/tasks and task states; RTOS scheduler and algorithms;
interrupt latency, interrupt response time as performance metrics; example of small
RTOS based systems. 06


Assessment:
Internal assessment con sists of two tests out of which, one should be compulsory class test (on minimum 02
modules) and the other is either a class test or assignment on live problems or course project.

Books Recommended:
Text books :
1. The 8051 microcontrollers by Kenneth J Ayala, Cengage Learning.
2. The 8051 Microcontroller and Embedded Systems: Using Assembly and C by M A Mazidi, J G Mazidi and
R D McKinlay, Pearson Education.
3. Using MCS -51 Microcontroller by Han -Way Huang, Oxford Univers ity Press .
4. 8051 microcontroller: Hardware, Software & Applications by V Udayashankara , M Mallikarjunaswamy,
McGraw Hill Education .
5. Embedded Systems -Architecture, Programming and Design, Rajkamal, Tata McGraw Hill.
Reference Books:
1. Embedded Realtime Systems Programming by Sriram Iyer and Pankaj Gupta, Tata McGraw Hill.
2. Embedded Microcomputer Systems - Real Time Interfacing by Valvano, Cengage Learning.
3. Embedded System Design: A Unified Hardware/Software Introduction by Frank Vahid, Toney Givargis -
John Wiley Publication.
4. An Embedded Software Primer by David E. Simon - Pearson Education.


NPTEL/Swayam Course:
Course : Microprocessors and Microcontrollers (Video) by Prof. Santanu Chattopadhyaya from IIT Kharagpur.
https://nptel.ac.in/courses/108/105/108105102/

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University of Mumbai, Biomedical Engineering, Rev 202 1-22
Theory Examination:
1. Question paper will comprise of 6 questions, each carrying 20 marks.
2. Total four questions need to be solved.
3. Q.1 will be compulsory, based on entire syllabus wherein sub questions of 2 to 5 marks will be asked.
4. Remaining question s will be randomly selected from all .


Course
Code Course Name Teaching scheme Credit assigned

BMC50 4
Medical Imaging -
II
(Abbreviated
as MI -II) Theory Pract. Tut. Theory Pract. Tut. Total
03 -- -- 03 -- -- 03


Course Code Course Name Credits
BMC504 Medical Imaging - II 03
Course Objectives • To familiarize the learners with the various Imaging techniques in medicine
operating principles and quality control aspects of various imaging
modalities.
• To keep the learners abreast with the technological developments in the
field of Medical Imaging. Course
Code Course Name Examination Scheme
Theory
Term
work Pract Oral Pract. /
Oral Total Internal Assessment End
sem Dura
tion
(hrs) Test 1 Test 2 Avg.

BMC
504

Medical
Imaging -II
(Abbreviated
as MI -II) 20 20 20 80 03 -- -- -- -- 100

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University of Mumbai, Biomedical Engineering, Rev 202 1-22 Cour se Outcomes Learner will be able to …
• Understand use of Ultrasound in medicine, distinguish various ultrasonic
display system, understand the construction and operation of the ultrasonic
transducer.
• Understand the Doppler effect and clinical applications o f Doppler
Techniques.
• Describe working principle and physics involved in Magnetic Resonance
Imaging (MRI)
• Understand the hardware of MRI Machine, Spin echo Imaging, Pulse
sequence, image reconstruction, resolution and SNR, Biological effects, and
clinical applications.
• To understand the basic principle of Magnetic Resonance Spectroscopy.
• To understand principle and working of Endoscopy and Thermography
systems and its clinical applications.

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University of Mumbai, Biomedical Engineering, Rev 202 1-22 Module Contents Hours
1 Ultrasound Imaging
Introduction, production and characteristics of ultrasound, interaction of
ultrasound with matter. ultrasound transducers and instrumentation. real
time ultrasound. 08
2 Doppler Ultrasound
Doppler effect, continuous wave and pulsed wa ve doppler system, 2 D-
echo, clinical applications. 04
3 Physics of MRI
Magnetic dipole moments, relaxation parameters, spin echo, magnetic
field gradients, slice selection, phase and frequency encoding . 06
4 Magnetic Resonance Imaging
Hardware: magnets, gradient coils, RF coils, spin echo imaging, inversion
recovery pulse sequence, image reconstruction, resolution and factors
affecting signal -to-noise. safety considerations and biological effects of
MRI , clin ical applications . 09
5 Magnetic Resonance Spectroscopy (MRS)
Basic principle of MRS, metabolites studied, STEAM and PRESS pulse
sequences, chemical shift imaging, single -voxel and multivoxel MRS,
water suppression techniques. 06
6 Endoscopy and Thermography
Working principle, equipment, and its applications. 06

Assessment:
Internal assessment consists of two tests out of which; one should be compulsory class test (on minimum
02 modules) and the other is either a class test or assignment on live problems or course project.

Books Recommended:
Textbooks:
1. Christensen’s Physics of Diagnostic Radiology , Thomas S. Curry, James E. Dowdey, Robert C.
Murry. Wolters Kluwer, Fourth Edition.
2. Medical Imaging Physics, William R. Hendee, E. Russell Ritenour . Wiley , Fourth Edition.
3. Physics of Diagnostic Imaging, David Dowsett, Patrick A Kenny, R Eugene Johnston. CRC Press,
Second Edition.
Reference Books:
1. Biomedical Technology and Devices , James Moore, George Zouridakis. CRC Press, Second
Edition.
2. The Biomedical Engineering Handbook , Joseph D. Bronzino, CRC Press, Second Edition.
3. MRI: The Basic s, Ray H. Hashemi, William G. Bradley, Christopher J. Lisanti. Lippincott Williams
& Wilkins, Second Edition.

NPTEL/Swayam Links:
Medical Image Analysis, Dr. Debdoot Sheet, Indian Institute of Technology, Kharagpur
Course Link: https://nptel.ac.in/courses/108/105/108105091/

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University of Mumbai, Biomedical Engineering, Rev 202 1-22 Theory Examination :
1. Question paper will comprise of 6 questions, each carrying 20 marks.
2. Total four questions need to be solved.
3. Q.1 will be compulsory, based on entir e syllabus wherein sub questions of 2 to 5 marks will be
asked.
4. Remaining question will be randomly selected from all the modules.

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University of Mumbai, Biomedical Engineering, Rev 202 1-22 Course
Code Course Name Teaching scheme Credit assigned
BMDO
5011 Principles of
Communication
Engineering
(abbreviated as PCE) Theory Pract. Tut. Theory Pract. Tut. Total
03 -- -- 03 -- -- 03

Course
Code Course Name Examination Scheme
Theory
Term
work Pract. Oral Pract.
/ Oral Total Internal Assessment End
sem Dura
tion
(hrs) Test 1 Test 2 Avg.
BMDO
5011 Principles of
Communicati
on
Engineering
(abbreviated
as PCE) 20 20 20 80 03 -- -- -- -- 100

Course Code Course Name Credits
BMDO5011 Principles of Communication Engineering 03
Course Objectives • To provide concepts, principles and techniques used in analog and digital
communications.
• To cover a range of digital modulation techniques which are frequently
used in modern communication systems.
Course Outcomes Learner will be able to …
• Demonstrate concept of electronic communication system with effect of
noise and modelling of noise
• Have in depth knowledge of amplitude modulation and understand the
AM transmitters and Receiver system with characteristics.
• Exhibit basic operation of FM t ransmitter and receiver with types,
analysis, advantages and disadvantages
• Understand and compare the different types of Analog pulse modulation
techniques
• Understand the different types of Digital pulse modulation techniques
with merits and demerits
• Unde rstand and compare different types of digital transmission techniques
and multiplexing techniques

Module Contents Hours
1. Introduction to communication system and noise:
• Elements of communication system, types of communication system
• Noise definition, types, signal to noise ratio, noise factor, noise figure, noise
temperature
04
2. Amplitude Modulation Transmission and Receivers:
• Definition, mathematical analysis of A M wave, different types of AM,
spectrum, bandwidth,
• AM transmitter: high and low level AM transmitter, DSB and SSB transmitter
(any one method) 07

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University of Mumbai, Biomedical Engineering, Rev 202 1-22 • AM receiver: c haracteristics: sensitivity, selectivity, fidelity, double spotting,
Image frequency and its rejection, dynamic range, super -heterodyne receiver,
double conversion receiver
3. Frequency Modulation Transmission and Receivers:
• Principles of FM waveform, spectrum, bandwidth
• FM generation: direct and indirect FM transmitter
• Principles of AFC, effect of noise in FM, noise triangle, pre-emphasis and de-
emphasis
• FM Receivers: block diagram
• Types: simple slope detector, balanced slope detector, Foster Seeley
discriminator, ratio detector, quadrature dete ctor
• Capture effect in FM receivers, difference between AM and FM system
10
4. Analog Pulse Modulation Techniques:
• Analog modulation techniques: PAM, PWM, PPM – generation, detection,
advantages, disadvantages.
05
5. Digital Pulse Modulation Techniques:
• Digital pulse modulation techniques: PCM, DPCM, DM and ADM –
generation, detection, advantages and disadvantages .
05

6. Digital Transmission Techniques and Multiplexing:
• Digital transmission types: ASK, FSK, PSK - generation, detection,
advantages and disadvantages .
• Multiplexing techniques: concept of multiplexing, FDM, TDM, hierarchy,
applications, advantages and d isadva ntages .
08

Assessment:
Internal assessment consists of two tests out of which; one should be compulsory class test (on minimum
02 modules) and the other is either a class test or assignment on live problems.

Books Recommended:
Text books:
1. Electronic communication system – Wayne Tomasi,Pearson Education
2. Electronic communication system – Roy Blake, Thomson Learning
3. Electronic communication system - Kennedy and Devis,TMH

Reference Books:
1. Digital and Analog communication system – Leon W Couch, Pearson Education
2. Principles of communication system – Taub and Schilling ,TMH

Theory Examination :
1. Question paper will comprise of total 06 questions, each carrying 20 marks.
2. Total four questions need to be solved.
3. Q.1 wi ll be compulsory, based on entire syllabus wherein subquestions of 2 to 5 marks will be asked.
4. Remaining questions will be randomly selected from all the modules.

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University of Mumbai, Biomedical Engineering, Rev 202 1-22 Course
Code Course Name Teaching scheme Credit assigned
BMDO
5012 Very Large Scale
Integration
(Abbreviated as
VLSI ) Theory Pract. Tut. Theory Pract. Tut. Total
03 -- -- 03 -- -- 03


Course
Code Course Name Examination Scheme
Theory
Term
work Pract. Oral Pract.
/ Oral Total Internal Assessment End
sem Dura
tion
(hrs) Test 1 Test 2 Avg.
BMDO
5012 Very Large
Scale
Integration
(Abbreviated
as VLSI) 20 20 20 80 03 -- -- -- -- 100

Course Code Course Name Credits
BMDO5012 Very Large -Scale Integrat ion 03
Course Objectives • To make the learner aware of fundamental concepts of Hardware Description Languages
• To make learner study working of MOSFET
• To make learner know the CMOS Circuits.
• The learner should be able to know the MOSFET f abrication processes

Course Outcomes Learner will be able to …
• To describe hardware description language used to model circuits.
• To develop some basic digital circuits using HDL
• To analyze the physics of MOS devices.
• To compare characteristics of various inverter circuits
• To compare the fabrication technology used in IC fabrication and how system clocking
is designed.
• To design layouts for various digital gates applying the design rules

Module
No. Contents Hours
1. Physics of MOSFET
MOSFET, threshold voltage, linear and saturated operation, FET capacitance, Scaling of
MOS circuits, types of scaling and limitations of scaling -short channel and hot electron effect. 05
2. MOSFET Inverters :
MOS Transistors, MOS transistor switches, Basic MOS inverter and its working, types of
MOS invertors viz active and passive load nMOS inverter s, CMOS inverter, voltage transfer
characteristics, noise immunity and noise margins . 05

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University of Mumbai, Biomedical Engineering, Rev 202 1-22 3. Silicon Semiconductor Technology:
Wafer processing, mask generation, oxidation, epitax ial growth , diffusion, ion implantation,
photo lithography, etching, metallization, basic nMOS and pMOS processes. Latch up in
CMOS and CMOS using twin tub process. 07

4. Introduction to VLSI Clocking and System Design:
Clocking: CMOS clocking styles, Clock generation, stabilization and distribution. Low
power CMOS Circuits: Various components of power dissipation in CMOS, limits on low
power design, low power design throu gh voltage scaling. 06

5. Design rules and Layout
NMOS and CMOS design rules and layout, Design of NMOS and CMOS inverters, NAND
and NOR gates. Interlayer contacts, butting and buried contacts, stick diagrams, layout of
inverter, NAND and NOR gates. Design of basic VLSI circuits , design of circuits like
multiplexer, decoder, flip flops, using MOS circuits . 08

6. Hardware Description Language
Introduction to VHDL hardware description language, core features of VHDL, data types,
different modeling styles and architectures of VHDL , Combinational and Sequential Logic
design using VHDL 08

Assessment:
Internal assessment consists of two tests out of which; one should be compulsory class test (on minimum 02
modules) and the other is either a class test or assignment on live problems or course project.
Books Recommended:
Text Books:
1. CMOS Digital Integrated Circuits, Kang, Tata McGraw Hill Publications, Third Edition
2. Introduction to VLSI design , E. D. Fabricus , McGraw Hill Publications , 1990
3. Basic VLSI Design, D.A. Pucknell and Eshraghian,Prentice Hall of India,2005
4. Digital Design Principles and Practices, John F Wakerly, Prentice Hall of India,Third edition
5. Circuit Design with VHDL, Volnei A. Pedroni, Prentice Hall of India, 2009
6. Introduction to VLSI Circuits and Systems - John P. Uyemura ,Wiley

Reference Books:
1. VHDL Programming by Examples, Douglas Perry, McGraw Hill Publications, 2008
2. Principles of CMOS VLSI Design : A Systems Perspective, Neil H.E. Weste, Kamran Eshraghian Addison
Wesley Publications, Second edition, 1993
Theory Examination :
1. Question paper will c omprise of 6 questions, each carrying 20 marks.
2. Total four questions need to be solved.
3. Q.1 will be compulsory, based on entire syllabus wherein sub questions of 2 to 5 marks will be asked.
4. Remaining question will be randomly selected from all the modules

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University of Mumbai, Biomedical Engineering, Rev 202 1-22
Course
Code Course Name Teaching scheme Credit assigned
BMDO
5013 Tissue Engineering
(Abbreviated as
TE) Theory Pract. Tut. Theory Pract. Tut. Total
03 -- -- 03 -- -- 03

Course
Code Course Name Examination Scheme
Theory
Term
work Pract. Oral Pract. /
Oral Total Internal Assessment End
sem Dura
tion
(hrs) Test 1 Test 2 Avg.
BMDO
5013 Tissue
Engineering
(Abbreviate
d as TE) 20 20 20 80 03 -- -- -- -- 100

Course Code Course Name Credits
BMDO5013 Tissue Engineering 03
Course O bjective • To understand the basics and terminologies of tissue engineering.
• Learn importance of stem cells in tissue engineering
• To understand the basic concepts of cell culture
• To understand applications of tissue engineering in medical field
Course Outcome Learner will be able …
• To get acquainted with cellular responses
• To understand role of extracellular matrix in tissue engineering
• To understand cell characteristics.
• To understand tissue culture and cryopreservation techniques.
• To understand the selection of various biomaterials for tissue engineering
• To understand tissue engineering applications

Module Contents Hours

1. Introduction to Tissue Engineering :
Fundamentals of stem cell tissue engineering, mechanical forces on cells, cell
adhesion, cell migration, inflammatory and immune responses to tissue, cell death -
biological description of apoptosis, tissue types. 07
2. Extracellular Matrix :
Structure, function, components, synthesis of the collagens , The ECM - cell binding
and long-term contact . 05

3. Measurement of cell characteristics :
Cell morphology, cell number and viability, cell-fate processes, cell motility, cell
functio n. 05
4. Cell and tissue culture :
Types of tissue culture, media, culture environment and maintenance of cells in -
vitro, cryopreservation. problems with the culture, organ culture . 06

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University of Mumbai, Biomedical Engineering, Rev 202 1-22
5. Biomaterials in Tissue Engineering :
Biodegradable polymers and polymer scaffold processing. biomimetic materials,
nanocomposite scaffolds, gene therapy, bioreactors for tissue engineering .
06
6. Tissue Engineering – regeneration :
Skin, bone marrow, nervous system, muscle, ligaments and cartilage, cardiac
muscles - myocardial tissue engineering, strategies to deliver stem cells to the
damaged site . 10

Assessment:
Internal assessment consists of two tests out of which; one should be compulsory class test (on minimum
02 modules) and the other is either a class test or assignment on live problems or course project.

Books Recommended:
Text books:
1. Bernhard O. Palsson, Sangeeta N. Bhatia, “Tissue Engineering” , Pearson Prentice Hall Publishers ,
2009.
2. Joseph D. Bronzino, “The Biomedical Engineering HandBook”, CRC Press LLC , 2006.
3. John P. Fisher, Antonios G. Mikos and Joseph D. Bronzino, “ Tissue Engineering”, CRC Press LLC ,
2007.
4. W. W. Minuth, R. Strehl and K. Schumacher, “Tissue Engineering - Essentials for Daily Laboratory
Work”, Wiley -VCH Verlag GmbH & Co. KGaA , 2005.
5. Daniel Eberli, “Tissue Engineering for Tissue and Organ Regeneration”, InTech , 2011.

Reference books:
1. Raph ael Gorodetsky, Richard Schäfer , “Stem Cell Based Tissue Repair ”, RSC Publishing, 2011.
2. R. Lanza, I. Weissman, J. Thomson, and R. Pedersen, Handbook of Stem Cells, Two Volume, Volume
1-2: Volume 1 -Embryonic Stem Cells; Volume 2 -Adult & Fetal Stem Cells, 2004, Academic Press ,
2004.
3. R. Lanza, J. Gearhart et . al. (Eds), “Essential of Stem Cell Biology ”, Academic press , 2009
4. J. J. Mao, G. Vunjak -Novakovic et al (Eds), Translational Approaches In Tissue Engineering &
Regenerative Medicine”, Artech House , INC Publications , 2008.
5. Naggy N. Habib, M.Y. Levicar, L. G. Jiao and N. Fisk, “Stem Cell Repair and Regeneration ”, volume -
2, Imperial College Press , 2007 .
6. Cato T. Laurencin, Lakshmi S. Nair , "Nanotechnology and Tissue engineering - The Scaffold", CRC
Press, 2015 .
7. Meyer, U. , Meyer, Th. , Handschel, J. , Wiesmann, H.P. , “Fundamentals of Tissue
Engineering and Regenerative Medicine ” Springer, 2009.
8. Lanza RP, Langer R, Vacanti J. “Principles of Tissue Engineering ”, Third edition. Academic Press.
2007 .

NPTEL/Swayam Links:
Course 1: Tissue Engineering
https://nptel.ac.in/courses/102/106/102106081/
Course 2: Tissue Engineering
https://nptel.ac.in/courses/102/106/102106036/


Theory Examination :
1. Question paper will comprise of total 06 questions, each carrying 20 marks.
2. Total 04 qu estions need to be solved.
3. Question No: 01 will be compulsory and based on entire syllabus wherein sub -questions of

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University of Mumbai, Biomedical Engineering, Rev 202 1-22 marks will be asked.
4. Remaining questions will be randomly selected from all the modules.

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University of Mumbai, Biomedical Engineering, Rev 202 1-22 Course
Code Course Name Teaching scheme Credit assigned
BML501 Biomedical
Instrumentation - I
Laboratory
(Abbreviated as
BMI -I) Theory Pract. Tut. Theory Pract. Tut. Total
-- 02 -- -- 01 -- 01

Course
Code Course Name Examination Scheme
Theory Term
work Pract. Oral Pract.
/ Oral Total Internal Assessment End
sem Test 1 Test 2 Avg.
BML501 Biomedical
Instrumentation - I
Laboratory
(BMI -I) -- -- -- -- 25 -- 25 -- 50

Course Code Course Name Credits
BML501 Biomedical Instrumentation - I Laboratory 01
Course Objective • To demonstrate the application technique of diagnostic and therapeutic
equipment.
• To implement the basic circuits used in diagnostic and therapeutic
equipment.
Course Outcome


Learner will be able to…
• Appreciate the importance of wavelength selection for measurement of
various ions present in the sample.
• Explain principles of various analytical instruments used in hospital
laboratories.
• Design and implement power supply of regul ated voltage and current
• Explain the basic principle and working of hemodialysis machine.

Syllabus: Same as that of ( BMC501 ) Biomedical Instrumentation - -I (BMI -I)

List of Experiments: (Any Seven)
1. Selection of wavelength for colorimeter and spectrophotometer
2. Find out the concentration of unknown sample using colorimeter and spectrophotometer
3. Design and implementation of 5V, 1A regulated power supply
4. Design and implementation of temperature controller circuit for hemodialysis machine
5. Design an d implementation of pulse width modulator
6. Demonstration of ventilators
7. Demonstration of anesthesia machine
8. Calculations of lung volumes and capacities
9. Industry / hospital visit to be conducted.
Any other experiment based on syllabus which will help learner to understand topic/concept.

Group presentation on the latest technology in hospitals based on the topics covered in the syllabus.

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University of Mumbai, Biomedical Engineering, Rev 202 1-22
Assessment:
Term Work:
Term work shall consist of minimum 7 experiments.
The distribution of marks for term work shall be as follows:
Laboratory work (Experiments): 10 Marks
Laboratory work (Journal) : 05 Marks
Presentation : 05 Marks
Attendance : 05 Marks
The final certification and acceptance of term work ensures the satisfactory performance of laboratory
work and minimum passing in the term work.
Books Recommended:
Text books:
1. Handbook of Biomedical Instrumentation (Third edition): R S. Khandpur. (PH Pub)
2. Medical Instrumentation, Application and Design: J G. Webster. (John Wiley)
3. Biomedical Instrumentation and measurements: Leislie Cromwell, Fred J. Weibell, Enrich A. Pfeiffer.
(PHI Pub)

Reference books:
1. Introduction to Biomedical Equipment Technology: Carr –Brown. (PH Pub)
2. Encyclopedia of Medical Devices and Instrumentation: J G. Webster. Vol I - IV (PH Pub)
3. Various Instruments Manuals.
4. Various internet websites

Oral examination will be b ased on suggested practical list and entire syllabus.

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University of Mumbai, Biomedical Engineering, Rev 202 1-22 Sub
Code Subject
Name Teaching Scheme Credits Assigned
Theory Pract. Tut Theory Pract. Tut Total
BML502 Digital
Signal
Processing
Laboratory -- 2 -- -- 1 -- 1

Sub
Code Subject
Name Examination scheme
Theory Marks
Exam
Duration
(in hrs) Term
Work Prac/
Oral Total Internal Assessment End
Sem
exam Test 1 Test 2 Avg.
BML 502 Digital
Signal
Processing
Laboratory -- -- -- -- -- 25 25 50


Course Code Course Name Credits
BML502 Digital Signal Processing L aboratory 01
Course
Objectives • To build a strong base in signal and image processing through algorithm
development.
• To develop competency in logical thinking, computer programming and
knowledge application.
• To train and motivate for higher education and research in order to make
contr ibution to state of the art health care for all.
Course
Outcomes Learner will be able to …
• Understand the fundamental techniques and applications in digital
processing of bio -signals.
• Understand circular and linear convolution and their implementation using
Z-transform and DFT.
• Understand and implement efficient computational techniques like FFT.
• Design FIR and IIR filters by different methods.

Syllabus: Same as that of BMC50 2 Digital Signal Processing (Abbreviated as DSP )

List of Experiments (using Matlab / C / Labview / python / other platform)

1. Basics of programming
2. Simulations of standard signals
3. Concept of aliasing
4. Linear convolution circular convolution
5. Discrete Fourier Transform (DFT )
6. Design and simulation of FIR filter
7. IIR filters using Butterworth approximation
8. IIR filter using Chebyshev approximation

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University of Mumbai, Biomedical Engineering, Rev 202 1-22 9. Pan-Tompkin algorithm for R -wave detection



Assessment:
Term Work:
Term work shall consist of minimum 7 experiments.
The distribution of marks for term work shall be as follows:
Laboratory work (Experiments): 10 Marks
Laboratory work (Journal) : 10 Marks
Attendance : 05 Marks
The final certification and acceptance of term work ensures the satisfactory performance of laboratory
work and minimum passing in the term work.

Text books:
1. Digital signal processing Principles Algorithms and Application – Proakis &Manolakis – Third edition
PHI
2. Digital Signal Processing – Sanjit K. Mithra Tata Mc -graw Hill
3. Digital Signal Processing – S. Salivahanan, C. Gnanapriya, Tata McGraw Hill
Reference Books:
1. Digital signal processing – A.V. Oppenheim and R.W. Schafer - PHI
2. Understandi ng Digital Signal Processing – Richard G. Lyons - Pearson Publication
3. Biomedical Digital Signal Processing -- Willis J. Tompkins -- EEE, PHI, 2004
4. R M Rangayyan “Biomedical Signal Analysis: A case Based Approach”, IEEE Press, John Wiley
& Sons. Inc, 2002

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University of Mumbai, Biomedical Engineering, Rev 202 1-22

Course
Code Course Name Teaching scheme Credit assigned
BML503 Microcontrollers
and Embedded
Systems
Laboratory
(Abbreviated as
MES Lab) Theory Pract. Tut. Theory Pract. Tut. Total
-- 02 -- -- 01 -- 01

Course
Code Course Name Examination Scheme
Theory Term
work Pract./
Oral Total Internal Assessment End
sem Duration
(hrs) Test 1 Test 2 Avg.
BML503 Microcontrollers
and Embedded
Systems
Laboratory
(Abbreviated as
MES Lab) -- -- -- -- -- 25 25 50

Course Code Course Name Credits
BML503 Microcontrollers and Embedded Systems Laboratory 01
Course Objectives • Give the students skills in both simulation and practical implementation of the
basic building blocks of 8051 microcontroller -based applications including
timers/counters, PWM generation, I/O techniques and requirements, DC
motors, stepper motors, keyboard , display device and serial communications
• Give students skills in 8051 microcontroller programming.
Course Outcomes Learner will be able to …
• Design different programs using C compilers for 8051 controller
• Design and develop 8051embedded C programs for timer based applications
• Design and develop 8051embedded C programs for control of DC motors and
stepper motors
• Design and develop 8051embedded C programs for interfacing keyboard and
display device
• Design and develop 8051embedded C programs for interfacing with the PC

Syllabus: Same as that of BMC503 Microcontrollers and Embedded Systems (Abbreviated as MES) .
List of Laboratory Experiments:
Any eight experiments to be performed in hardware mode and/or softw are simulation mode.
1. To demonstrate basic I/O toggling and interrupts of 8051.
2. To generate precise delay and trigger pulses using 8051 timer.

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University of Mumbai, Biomedical Engineering, Rev 202 1-22 3. To generate waveform and perform PWM using 8051 timer.
4. To interface 8051 with relay and DC motor (using H bridge) – demonstration through basic I/O
toggling.
5. To control the speed of DC motor through PWM based MOSFET switching.
6. To interface 8051 with the stepper motor.
7. To interface 8051 with the seven -segment display.
8. To interface 8051 with the keyboard.
9. To interface 8051 with PC using UART and RS232 standard.
Any other experiment based on syllabus may be included, which would help the learner to understand
topic/concept.
Assessment :
Term Work :
Term work shall consist of minimum 8 experiments.
The distribution of marks for term work shall be as follows:
Laboratory work (Experiments) : 10 Marks
Laboratory work (Journal) : 10 Marks
Attendance : 5 Marks
The final certification and acceptan ce of term work ensures the satisfactory performance of laboratory work and
minimum passing in the term work.

Books Recommended:
Textbooks:
1. The 8051 microcontrollers by Kenneth J Ayala, Cengage Learning.
2. The 8051 Microcontroller and Embedded Systems: Using Assembly and C by M A Mazidi, J G Mazidi and
R D McKinlay, Pearson Education.
3. Using MCS -51 Microcontroller by Han -Way Huang, Oxford University Press .
4. 8051 microcontroller: Hardware, Software & Applicatio ns by V Udayashankara , M Mallikarjunaswamy,
McGraw Hill Education .
5. Embedded Systems -Architecture, Programming and Design, Rajkamal, Tata McGraw Hill.
Reference Books:
1. Embedded Realtime Systems Programming by Sriram Iyer and Pankaj Gupta, Tata McGraw Hill.
2. Embedded Microcomputer Systems - Real Time Interfacing by Valvano, Cengage Learning.
3. Embedded System Design: A Unified Hardware/Software Introduction by Frank Vahid, Toney Givargis -
John Wiley Publication.
4. An Embedded Software Primer by David E. Simon - Pearson Education.

NPTEL/Swayam Course:
Course: Microprocessors and Microcontrollers (Video) by Prof. Santanu Chattopadhyaya from IIT Kharagpur.
https://nptel.ac.in/courses/108/105/108105102/
Practical exam consists of performance of any one practical from the conducted exp eriments within the
semester

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University of Mumbai, Biomedical Engineering, Rev 202 1-22
Course
Code Course Name Teaching scheme Credit assigned
BML504 Professional
Communication &
Ethics – II
(abbreviated as
PCE - II) Theory Pract. Tut. Theory Pract. Tut. Total
-- 2 ⃰ + 2 Hours
(Batch -wise) -- -- 2 -- 02
*Theory class to be conducted for full class.

Course Code Course Name Credits
BML504 Professional Communication & Ethics - II 02
Course Objectives • To discern and develop an effective style of writing important
technical/business documents.
• To investigate possible resources and plan a successful job campaign.
• To understand the dynamics of professional communication in the form of
group discussions, meetings, etc. required for career enhancement.
• To develop creative and impactful presentation skills.
• To analyse personal traits, interest s, values, aptitudes and skills.
• To understand the importance of integrity and develop a personal code of
ethics. Course
Code Course Name Examination Scheme
Theory
Term
work Pract Oral Intern
al Oral Total Internal Assessment End
sem Dura
tion
(hrs) Test 1 Test 2 Avg.
BML50
4 Professional
Communica
tion &
Ethics
(abbreviated
as PCE - II) -- -- -- -- -- 25 -- -- 25 50

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University of Mumbai, Biomedical Engineering, Rev 202 1-22 Course Outcomes Learner will be able to …
• plan and prepare effective business/ technical documents which will in
turn provide solid foundation for their future managerial roles.
• strategize their personal and professional skills to build a professional
image and meet the deman ds of the industry.
• emerge successful in group discussions , meetings and result -oriented
agreeable solutions in group communication situations.
• deliver persuasive and professional presentations .
• develop creative thinking and interpersonal skills required for effective
professional communication.
• apply codes of ethical conduct , personal integrity and norms of
organizational behaviour.


Module Contents Hours
1 ADVANCED TECHNICAL WRITING :PROJECT/PROBLEM
BASED LEARNING (PBL)
1.1 Purpose and Classification of Reports :
Classification on the basis of:
• Subject Matter (Technology, Accounting, Finance, Marketing, etc.)
• Time Interval (Periodic, One -time, Special)
• Function (Informational, Analytical, etc.)
• Physical Factors (Memorandum, Letter, Short & Long)
1.2. Parts of a Long Formal Report :
• Prefatory Parts (Front Matter)
• Report Proper (Main Body)
• Appended Parts (Back Matter)
1.3. Language and Style of Reports
• Tense, Person & Voice of Reports
• Numbering Style of Chapters, Sections, Figures, Tables and Equations
• Referencing Styles in APA & MLA Format
• Proofreading through Plagiarism Checkers
1.4. Definition, Purpose & Types of Proposals
• Solicited (in conformance w ith RFP) & Unsolicited Proposals
• Types (Short and Long proposals)
1.5. Parts of a Proposal
• Elements
• Scope and Limitations
• Conclusion
1.6. Technical Paper Writing
• Parts of a Technical Paper (Abstract, Introduction, Research Methods,
Findings and Analysis, Discussion, Limitations, Future Scope and 06

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University of Mumbai, Biomedical Engineering, Rev 202 1-22 References)
• Language and Formatting
• Referencing in IEEE Format
2 EMPLOYMENT SKILLS
2.1. Cover Letter & Resume
• Parts and Content of a Cover Letter
• Difference between Bio -data, Resume & CV
• Essential Parts of a Resume
• Types of Resume (Chronological, Functional & Combination)
2.2 Statement of Purpose
• Importance of SOP
• Tips for Writing an Effective SOP
2.3 Verbal Aptitude Test
• Modelled on CAT, GRE, GMAT exams
2.4. Group Discussions
• Purpose of a GD
• Parameters of Evaluating a GD
• Types of GDs (Normal, Case -based & Role Plays)
• GD Etiquettes
2.5. Personal Interviews
• Planning and Preparation
• Types of Questions
• Types of Interviews (Structured, Stress, Behavioural, Problem Solving &
Case -based)
• Modes of Interviews: Face -to-face (One -to one and Panel) Telephonic,
Virtual 06
3 BUSINESS MEETINGS
a. Conducting Business Meetings
• Types of Meetings
• Roles and Responsibilities of Chairperson, Secretary and Members
• Meeting Etiquette
3.2. Documentation
• Notice
• Agenda
• Minutes 02
4 TECHNICAL/ BUSINESS PRESENTATIONS
a. Effective Presentation Stra tegies
• Defining Purpose
• Analysing Audience, Location and Event
• Gathering, Selecting &Arranging Material
• Structuring a Presentation
• Making Effective Slides
• Types of Presentations Aids
• Closing a Presentation
• Platform skills
b. Group Presentations 02

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University of Mumbai, Biomedical Engineering, Rev 202 1-22 • Sharing Responsibility in a Team
• Building the contents and visuals together
• Transition Phases
5 INTERPERSONAL SKILLS
a. Interpersonal Skills
• Emotional Intelligence
• Leadership & Motivation
• Conflict Management & Negotiation
• Time Management
• Assertiveness
• Decision Making
5.2 Start -up Skills
• Financial Literacy
• Risk Assessment
• Data Analysis (e.g. Consumer Behaviour, Market Trends, etc.) 08
6 CORPORATE ETHICS
6.1 Intellectual Property Rights
• Copyrights
• Trademarks
• Patents
• Industrial Designs
• Geographical Indications
• Integrated Circuits
• Trade Secrets (Undisclosed Information)
6.2 Case Studies
• Cases related to Business/ Corporate Ethics 02

List of assignments :
(In the form of Short Notes, Questionnaire/ MCQ Test, Role Play, Case Study, Quiz, etc.)
1. Cover Letter and Resume
2. Short Proposal
3. Meeting Documentation
4. Writing a Technical Paper/ Analysing a Published Technical Paper
5. Writing a SOP
6. IPR
7. Interpersonal Skills
8. Aptitude test (Verbal Ability)
Note:
1. The Main Body of the project /book report should contain minimum 25 pages (excluding Front and Back
matter).
2. The group size for the final report presentation should not be less than 5 students or exceed 7 students.
3. There will be an end –semester presentation based on the book re port.

Assessment :

Term Work :
Term work shall consist of minimum 8 experiments.

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University of Mumbai, Biomedical Engineering, Rev 202 1-22 The distribution of marks for term work shall be as follows:
Assignment : 10 Marks
Attendance : 5 Marks
Presentation slides : 5 Marks
Book Report (hard copy) : 5 Marks
The final certification and acceptance of term work ensures the satisfactory performance of laboratory work and
minimum passing in the term work.

INTERNAL ORAL - 25 MARKS
Oral Examination will be based on a GD & the Project/Book Report presentation.
Group Discussion : 10 marks
Project presentation
Individual Presentation : 10 Marks
Group Dynamics : 5 Marks

Books Recommended:
Textbooks and Refer ence books:
1. Arms, V. M. (2005). Humanities for the engineering curriculum: With selected chapters from
Olsen/Huckin: Technical writing and professional communication, second edition . Boston, MA:
McGraw -Hill.
2. Bovée, C. L., &Thill, J. V. (2021). Business communication today . Upper Saddle River, NJ: Pearson.
3. Butterfield, J. (2017). Verbal communication: Soft skills for a digital workplace . Boston, MA: Cengage
Learning.
4. Masters, L. A., Wallace, H. R., & Harwood, L. (20 11).Personal development for life and work . Mason:
South -Western Cengage Learning.
5. Robbins, S. P., Judge, T. A., & Campbell, T. T. (2017). Organizational behaviour . Harlow, England:
Pearson.
6. Meenakshi Raman, Sangeeta Sharma (2004) Technical Communication, Principles and Practice. Oxford
University Press
7. Archana Ram (2018) Place Mentor, Tests of Aptitude For Placement Readiness. Oxford University
Press
8. Sanjay Kumar & PushpLata (2018). Communication Skills a workbook, New Delhi: Oxford University
Press.

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University of Mumbai, Biomedical Engineering, Rev 202 1-22 Course code Course Name Credits
BMM5 01 Mini Project - 2 A 02

Course Code Course Name Credits
BMM501 Mini Project – 2 A 02
Course Objective • To acquaint with the process of identifying the needs and converting it into the
problem .
• To familiarize the process of solving the problem in a group .
• To acquaint with the process of applying basic engineering fundamental s to
attempt solutions to the problems.
• To inculcate the proces s of self -learning and research.
Course Outcome Learner will be able to:
• Identify problems based on societal /research needs.
• Apply Knowledge and skill to solve societal problems in a group.
• Develop interpersonal skills to work as member of a group or leader.
• Draw the proper inferences from available results through theoretical /
experimental/simulations .
• Analyse the impact of solutions in societal and environmental context for
sustainable development.
• Use standard norms of engineering practices
• Excel in written and oral communication.
• Demonstrate capabilities of self -learning in a group, which leads to life long
learning.
• Demonstrate project management principles during project work.

Guidelines for Mini Project
• Students shall form a group of 3 to 4 students, while forming a group shall not be allowed less than
three or more than four students, as it is a group activity.
• Students should do survey and identify needs, which shall be converted into problem statement for
mini project in consultation with faculty supervisor/head of department/internal committee of
faculties.
• Students hall submit implementation plan in the form of Gantt/PERT/CPM chart, which will cover
weekly activity of mini project.
• A log book to be prepared by each group, wherein group can record weekly work progress,
guide/supervisor can verify and record notes/comments.
• Faculty supervisor may giv e inputs to students during mini project activity; however, focus shall be
on self -learning.
• Students in a group shall understand problem effectively, propose multiple solution and select best
possible solution in consultation with guide/ supervisor.
• Students sh all convert the best solution into working model using various components of their
domain areas and demonstrate.

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University of Mumbai, Biomedical Engineering, Rev 202 1-22 • The solution to be validated with proper justification and report to be compiled in standard format
of University of Mumbai .
• With the focus on the self -learning, innovation, addressing societal problems and entrepreneurship
quality development within the students through the Mini Projects, it is preferable that a single
project of appropriate level and quality to be carried out in tw o semesters by all the groups of t he
students. Mini Project 2 in semesters V and VI.
• However, based on the individual students or group capability, with the mentor’s recommendations,
if the proposed Mini Project adhering to the qualitative aspects mention ed above gets completed in
odd semester, then that group can be allowed to work on the extension of the Mini Project with
suitable improvements/modifications or a completely new project idea in even semester. This policy
can be adopted on case by case basi s.
Guidelines for Assessment of Mini Project :
Term Work
• The review/ progress monitoring committee shall be constituted by head of departments of
each institute. The progress of mini project to be evaluated on continuous basis, minimum two
reviews in each semester.
• In continuous assessment focus shall also be on each individual student, assessment based on
individual’s contribution in group activity, their understanding and response to questions.
• Distribution of Term work marks for both semesters shall be as below;
o Marks awarded by guide/supervisor based on log book : 10
o Marks awarded by review committee : 10
o Quality of Project report : 05
Review/progress monitoring committee may consider following points for
assessment based on either one yea r or half year project as mentioned in general
guidelines.
One-year project:
• In first semester entire theoretical solution shall be ready, including components/system
selection and cost analysis. Two reviews will be conducted based on presentation given b y
students group.
▪ First shall be for finalisation of problem
▪ Second shall be on finalisation of proposed solution of problem.
• In second semester expected work shall be procurement of component’s/systems, building of
working prototype, testing and validat ion of results based on work completed in an earlier
semester.
▪ First review is based on readiness of building working prototype to be conducted.
▪ Second review shall be based on poster presentation cum demonstration of working
model in last month of the sai d semester.

Half -year project:
• In this case in one semester students’ group shall complete project in all aspects including,
o Identification of need/problem
o Proposed final solution
o Procurement of components/systems

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University of Mumbai, Biomedical Engineering, Rev 202 1-22 o Building prototype and testing
• Two reviews will be conducted for continuous assessment,
▪ First shall be for finalisation of problem and proposed solution
▪ Second shall be for implementation and testing of solution.

Assessment criteria of Mini Project.

Mini Project shall be assessed based on following criteria;
1. Quality of survey/ need identification
2. Clarity of Problem definition based on need.
3. Innovativeness in solutions
4. Feasibility of proposed problem solutions and selection of best solution
5. Cost effectiveness
6. Societal impact
7. Innovativeness
8. Cost effectiveness and Societal impact
9. Full functioning of working model as per stated requirements
10. Effective use of skill sets
11. Effective use of standard engineering norms
12. Contribution of an individual’s as member or leader
13. Clarity in written and oral communication

• In one year, project , first semester evaluation may be based on first six criteria’s and remaining
may be used for second semester evaluation of performance of students in mini project .
• In cas e of half year project all criteria’s in generic may be considered for evaluation of performance
of students in mini project.
Guidelines for Assessment of Mini Project Practical/Oral Examination:
• Report should be prepared as per the guidelines issued by the University of Mumbai.
• Mini Project sh all be assessed through a presentation and demonstration of working model by the
student project group to a panel of Internal and External Examiners preferably from industry or
research organizations having experience of more than five years approved by head of Institution.
• Students shall be motivated to publish a paper based on the work in Conferences/students
competitions.
Mini Project shall be assessed based on following points;
1. Quality of problem and Clarity
2. Innovativeness in solutions
3. Cost effectiveness and Societal impact
4. Full functioning of working model as per stated requirements
5. Effective use of skill sets
6. Effective use of standard engineering norms
7. Contribution of an individual’s as member or leader
8. Clarity in written and oral communicate

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University of Mumbai, Biomedical Engineering, Rev 202 1-22
Semester – VI

Course
Code Course Name Teaching scheme Credit assigned
BMC601 Biomedical
Instrumentation -II
(Abbreviated as
BMI -II)
Theory Pract. Tut. Theory Pract. Tut. Total
03 -- -- 03 -- -- 03

Course
Code Course Name Examination Scheme
Theory
Term
work Pract. Oral Pract. /
Oral Total Internal Assessment End
sem Dura
tion
(hrs) Test
1 Test
2 Avg
.
BMC601 Biomedical
Instrumentation -II
(BMI -II) 20 20 20 80 03 -- -- -- -- 100

Course Code Course Name Credits
BMC601 Biomedical Instrumentation -II 03
Course Objective • To understand the basic principles and working of different Biomedical
monitoring system s.
• To develop skills enabling Biomedical Engineers to serve the health care industry
• To develop core competency and skill in the field of Biomedical Engineer ing to
design and develop new health care systems.
Course Outcome Learner will be able to …
• Provide a better understanding about various bioelectrical signal recorders and
patient safety along with greater emphasis on health care equipment and the
advanced technologies such as Telemetry and Telemedicine.
• Demonstrate the principles of electronics used in designing various biomedical
monitoring equipment.
• Understand the basic princples and working of audiometry equipments and
hearing aids
• Provide a better understanding about foetal and neonatal monitoring systems.
• Acquire the ability to explain the various blood flow and cardiac output
measurem ent devices.

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University of Mumbai, Biomedical Engineering, Rev 202 1-22
Module Contents Hours
1. Basic principle, working and technical specifications of
ECG, EMG and EEG machines, LEAD configurations, 10 -20 electrode system
measuring techniques for EOG, ERG and phonocardiography,
Patient Safety: Electric shock hazards, leakage currents, safety code s for electro -
medical equipment. 08
2. Arrhythmia and Patient monitoring:
Cardiac arrhythmias, Stress test measurement , ambulatory monitoring instruments such
as holter monitor.
Basics of Telemetry, Multi -channel Telemetry. 08
3. Basic principle and working of Patient Monitoring Systems
Measurement of heart rate, pulse rate, blood pressure, temperature and respiration rate,
apnea detector.
Heart rate variability measurement.
Point of care devices and their design considerations for hom ecare devices:
glucometer. 08
4. Basic principle and working of Audiometers and hearing aid
Basic audiometer, pure tone and speech audiometer, evoked response audiometry,
introduction to hearing aids and cochlear i mplants. 05
5. Basic principle and working of Foetal and Neonatal Monitoring System
Cardiotocograph, methods of monitoring of foetal heart rate, monitoring of labour
activity, incubator and infant warmer, non-stress test monitoring. 05
6. Basic principle and working of Blood flowmeters
Electromagnetic, ultrasonic, NMR and laser doppler flowmetry,
Measurement of Cardiac Output
Indicator dilution, dye dilution and thermal dilution techniques . 05

Assessment :
Internal assessment consists of two tests out of which; one should be compulsory class test (on minimum 02
modules) and the other is either a class test or assignment on live problems or course project.

Books Recommended:
Text books:
1. Handbook of Biomedical Instrumentation (Third edition) : R S. Khandpur. (PH Pub)
2. Medical Instrumentation, Application and Design: J G. Webster. (John Wiley)
3. Biomedical Instrumentation and measurements: Leslie Cromwell, Fred J. Weibell, Enrich A. Pfeiffer.
(PHI Pu b)

Reference books:
1. Introduction to Biomedical Equipment Technology: Carr –Brown. (PH Pub)
1. Encyclopedia of Medical Devices and Instrumentation: J G. Webster. Vol I - IV (PH Pub)
2. Various Instruments Manuals.
3. Various internet websites.

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University of Mumbai, Biomedical Engineering, Rev 202 1-22 Theory Examination :
1. Question paper will comprise of total 06 questions, each carrying 20 marks.
2. Total 04 questions need to be solved.
3. Question No: 01 will be compulsory and based on entire syllabus wherein sub -questions of
marks will be asked.
4. Remaining questions will be randomly selected from all the modules.

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University of Mumbai, Biomedical Engineering, Rev 202 1-22 Sub Code Subject
Name Teaching Scheme Credits Assigned
Theory Pract. Tut Theory Pract. Tut Total
BMC602 Biomedical
Digital
Image
Processing
(abbreviated
as BDIP) 3 --- --- 3 --- --- 3

Sub Code Subject
Name Examination scheme
Theory Marks
Term
work Pract/
Oral Total Internal Assessment End
Sem
exam Exam
Dur in
hrs Test 1 Test 2 Avg.
BMC602 Biomedical
Digital
Image
Processing 20 20 20 80 3 hrs --- --- 100



Course Code Course Name Credits
BMC60 2 Biomedical Digital Image Processing 03
Course Objectives • To be able to think about applying different Image processing techniques on a
given image.
• To know the fundamental concepts of a digital image processing techniques
• To be able to analyze problem and design algorithms to solve the problems.
Course Outcomes Learner will be able to …
• Acquire the fundamental concepts of a digital image processing system such as
image acquisition, enhancement, segmentation, transforms, compression,
morphology, representation and description.
• Analyze images in the spatial domain.
• Analyze images in the freq uency domain through the Fourier transform.
• Apply the concepts of morphology, representation and description on images.
• Design and implement with MATLAB/C/Python algorithms for digital image
processing.


Module Contents Time
1. Basics of Image Processing : Image acquisition, processing, communication,
display; electromagnetic spectrum; elements of visual perception - structure of the
human eye, image formation in the eye, brightness adaptation and discrimination,
image formation model, uniform an d non -uniform sampling, quantization, image
formats. 06
2. Image Enhancement : Spatial domain - point processing techniques, histogram
processing, neighbourhood processing, frequency domain techniques, 2 D-DFT ,
properties of 2 D-DFT , low pass, high pass, noise removal, homomorphic filters,
basics of colour image processing. 09

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University of Mumbai, Biomedical Engineering, Rev 202 1-22 3. Image Segmentation : Basic relationships between pixels, neighbours, adjacency,
connectivity, regions, boundaries, distance measures; detection of discontinuities,
point, li ne and edges, edge linking, Hough transform, thresholding based
segmentation, region -based segmentation. 06
4. Image Transforms & Image Compression : DFT, FFT, DCT, DST, Hadamard,
Walsh, Haar, basis functions and basis images, introduction to wavelet trans form,
fundamentals of image compression models, lossless compression , RLE, Huffman,
LZW and arithmetic coding techniques, lossy compression - IGS coding, transform
coding, JPEG, JPEG 2000. 08
5. Morphology, Representation and Description : Dilation, erosion, open, close, hit -
or-miss, boundary extraction, region filling, thinning and thickening; chain codes,
polygonal approximations, signatures; fourier descriptors, moments. 04
6. Feature Recognition and Classification: Object recognition and classification,
connected components labelling, features, statistical classification,
structural/syntactic classification, applications in medical image analy sis 06

Assessment :
Internal assessment consists of two tests out of which; one should be compulsory class test (on minimum 02
modules) and the other is either a class test or assignment on live problems or course project.

Text books:
1. Digital Image Processing, Gonzalez and Woods - Pearson Education.
2. Fundamentals of Digital Image Processing, A.K. Jain – P.H.I.
3. Digital Image Processing and Analysis, Chanda Majumder - Printice Hall India.

Reference Books:
1. Digital Image Processing for Medical Applications, Geoff Dougherty, Ca mbridge University
Press, 2009..
2. Digital Image Processing, William Pratt - John Wiley.


NPTEL /Swayam Course:
Course :
Digital Image Processing - NPTEL Lecture Videos by Prof. P.K. Biswas from IIT Kharagpur.
http://www.nptelvideos.com/course.php?id=541


Theory Examination:
1. Question paper will comprise of 6 questions, each carrying 20 marks.
2. Total four questions need to be solved.
3. Q.1 will be compulsor y, based on the entire syllabus wherein sub questions of 2 to 5 marks will be
asked.
4. Remaining question will be randomly selected from all the modules.

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University of Mumbai, Biomedical Engineering, Rev 202 1-22

Course
Code Course Name Teaching scheme Credit assigned
BMC60 3 Data Analysis in
Healthcare
(Abbreviated as
DAH) Theory Pract. Tut. Theory Pract. Tut. Total
03 -- -- 03 -- -- 03


Course Code Course Name Credits
BMC60 3 Data Analysis in Healthcare 03
Course Objectives • To cover basic concepts and theory related to statistics.
• To focus on various statistical abilities such as analysis of variance, hypothesis
testing, estimation, etc .
Course Outcomes The learner will be able to :
• Understand the basic techniques and nomenclatures used for statistical analysis of
data
• Describe the importance of normalizing data
• Apply statistical methods to sample data
• Analyze data using parametric statistical methods
• Develop a strong foundation for designing algorithms for computation.
• Design statistical models separately for parametric and non -parametric analysis .
Course
Code Course
Name Examination Scheme
Theory
Term
work Pract. Oral Pract.
/ Oral Total Internal Assessment End
sem Dur-
ation
(hrs) Test
1 Test
2 Avg.


BMC60 3
Data
Analysis in
Healthcare
(Abbreviat
ed as D AH) 20 20 20 80 03 -- -- -- -- 100

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University of Mumbai, Biomedical Engineering, Rev 202 1-22 Module Contents Hours
1 Descriptive statistics, probability and sampling distributions: Frequency
distribution, measures of central tendency, measures of dispersion, basic
probability and Bayes theorem, Binomial, Poisson and normal distributions,
sampling distributions of sample mean, difference between two sample means,
sample proportions and difference between two sample proportions 09
2 Estimation: Confidence intervals for population mean, difference between two
population means, population proportion, difference between two population
proportions, t -distribution, variance of normally distributed population, ratio of
variances of two normally distri buted populations, determination of sample size
for estimating mean and proportions 06
3 Hypothesis testing: Type – I and II errors , hypothesis testing for population
mean, difference between two population means, population proportions,
difference between two population proportions, population variance and ratio of
two population variances, power of test 06
4 Analysis of variance: Completely randomized des ign, randomized complete
block design, repeated measures design, factorial experiment, regression and
correlation , simple linear regression, correlation model, correlat ion coefficient,
multiple regression, multiple correlation 06
5 Chi square distribution and analysis of frequency: Chi-square distribution and
properties, test of goodness of fit, independence and homogeneity of data 06
6 Non-parametric analysis: Distribution free tests such as one sample sign test,
rank sun test, Mann -Whitney U-test, Kruskal -Wallis test, cluster analysis, data
mining methods 06


Assessment :
Internal assessment consists of two tests out of which; one should be compulsory class test (on minimum 02
modules) and the other is either a class test or assignment on live problems or course project.

Books Recommended:
Text Books:

1. Biostatistics – A foundation for analysis in health sciences by Wayne W. Daniel, Seventh edition, Wiley India
2. Fundamentals of mathematical statistics by S. C. Gupta and V. K. Kapoor, second edition, Sultan Chand
Publisher
3. Probability and statist ics for engine ers by J. Ravichandran, Wiley /I ndia
4. Research Methodology Methods and Techniques by C. R Kothari and Gaurav Garg, Fourth Edition, New Age
international publishers.

Reference Books:

Biostatistics – How it works by Steve selvin, Pearson e ducation
2. An Introduction to Biostatistics by Sunder Rao and J. Richard, Third Edition, Prentice Hall of India
3. Probability and Statistics by Schaum’s series

NPTEL/Swayam Course:
Course :
Introduction to Data Analytics by Prof. Nandan Sundarsanam – IIT-M and Prof. B. Ravindran – IIT-M
https://nptel.ac.in/noc/courses/noc16/SEM2/noc16 -mg06/

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University of Mumbai, Biomedical Engineering, Rev 202 1-22 Data analytics with Python by Prof. A. Ramesh - IIT Roorkee
https://nptel.ac.in/courses/106/107/106107220/

Assessment:
Internal Assessment consists of two tests out of which, one should be compulsory class test (on minimum 02
Modules) and the other is either a class test or assignment on live problems or course pr oject.

Theory Examination:
5. Question paper will comprise of 6 questions, each carrying 20 marks.
6. Total four questions need to be solved.
7. Q.1 will be compulsory, based on the entire syllabus wherein sub questions of 2 to 5 marks will be
asked.
8. Remaining question will be randomly selected from all the modules.

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University of Mumbai, Biomedical Engineering, Rev 202 1-22 Sub Code Subject Name Teaching Scheme Credits Assigned
Theory Pract. Tut Theory Pract. Tut Total
BMC604 Biomechanics,
Prosthetics and
Orthotics (abbreviated
as BPO) 3 - 1 3 - 1 4

Sub Code Subject Name Examination scheme
Theory Marks
Term
work Pract. Oral Total Internal Assessment End
Sem
exam Test 1 Test 2 Avg.
BMC604 Biomechanics,
Prosthetics and
Orthotics
(abbreviated as BPO) 20 20 20 80 25 - - 125

Course Code Course Name Credits
BMC60 4 Biomechanics, Prosthetics and Orthotics 03
Course Objectives • Recall the general characteristics, mechanical properties of bone and tissues.
• Analyze the forces at joints for various static and dynamic human activities;
analyze the stresses and strains in biological tissues.
• Understand principles used in designing o rthoses and prostheses
• Study different materials used for orthoses and prosthesis.
Course Outcomes Learner will be able to…
• Explain the basic principles of Biomechanics
• Explain the mechanical behavior of Biological Tissues
• Explain about various joints and its movements
• Explain the techniques adopted for analyzing joint movements.
• Explain the general principles followed while designing Orthoses and
prosthesis.
• Explain the applica tions of various Prosthetic and Orthotic devices.


Module Contents Time
BIOMECHANICS
1. Force system:
Classification of force syste m, equilibrium of force system , principle of biomechanics 02
2. Tissue Biomechanics :
Direct shear, bending and torque actions and the corresponding stresses and strains in
biological tissues. stress relaxation and creep.
Bone structure & composition, mechanical properties of bone, biomechanical
evaluation of bone using three points and fo ur points.
Biomechanics of connective tissues (skin, tendon, ligaments, etc.) covering structure
funct ion, and physiological factors. 10
3. Movement Biomechanics:
Study of joints and movements , anatomical levers, gait analysis , gait cycle and gait
parameters 04

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University of Mumbai, Biomedical Engineering, Rev 202 1-22 4. Joint analysis :
Instrumentation for gait analysis: measurement devices -footswitches, instrume nted
walkway, motion analysis - Selspot, goniometers , joint monitoring sensors and joint
monitoring parameters 05
PROSTHETICS AND ORTHOTICS
5. Principles in designing orthoses and prostheses:
Principles of three point pressure, total c ontact, partial weight bearing. 05
6. Classification in prosthetics and orthotics: Lower extremity orthoses and prostheses,
upper extremity orthoses a nd prostheses , spinal orthoses. 13


Tutorials: Eight tutorials are to be conducted from the below list .

1. Components of biomechanics
2. Role of biomechanics in exercises
3. Biomechanics and body movements
4. Gait cycle
5. Evaluation of gait parameters
6. Orthotic devices associated with sports injuries
7. Advancements in materials used for orthotic devices
8. Prosthetic rehabilitation
9. Advancements in materials used fo r prosthetic devices

Text books:
1. Basic Biomechanics - Susan J. Hall, MC Graw Hill.
2. Basics of Biomechanics" by Dr. Ajay Bahl and others
3. Basic Biomechanics of the Musculoskeletal System,M. Nordin, V.Frankel
4. Human Limbs and their substitutes – Atlas, C. V. Mosby
5. American Atlas of Orthopedics: Prosthetics, C. V. Mosby.
6. American Atlas of Orthopedics: Orthotics, C. V. Mosby
7. Biomechanics - Prof Ghista (Private Publication UAE)
8. Biomechanics – By White and Puyator (Private Publication UAE)

Reference Books:
1. Introductory Biomechanics: from cells to tissues by Ethier and Simmons
2. Biomechanics: Mechanical properties of living tissues by Y. C. Fung


NPTEL/Swayam Course :
1. Assistive Devices,Prosthesis and Orthosis, NPTEL Lecture Video by Dr Sujatha Srinivasan, I IT
Madras.
http://www.digimat.in/nptel/courses/video/112106248/L47.html

2. Mechanics of Human Movement, Swayam, Lecture Video by Dr Sujatha Srinivasan, IIT Madras.
https://onlinecourses.nptel.ac.in/noc21_me52/preview


Internal Assessment (IA):
Two tests must be conducted which should cover at least 80% of syllabus. The average marks of both
the tests will be considered for final Internal Assessment.

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University of Mumbai, Biomedical Engineering, Rev 202 1-22 Assessment:
Internal assessment consists of two tests out of which, one should be compulsory class test (on minimum 02
modules) and the other is either a class test or assignment on live problems or course project.

Theory Examination:
1. Question paper will comprise of 6 question s, each carrying 20 marks.
2. Total four questions need to be solved.
3. Q.1 will be compulsory, based on the entire syllabus wherein sub questions of 2 to 5 marks will be
asked.
4. Remaining question will be randomly selected from all the modules.

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University of Mumbai, Biomedical Engineering, Rev 202 1-22 Course
Code Course Name Teaching scheme Credit assigned

BMDO
6011 Nuclear
Medicine
(Abbreviated
as NM) Theory Pract. Tut. Theory Pract. Tut. Total
03 -- -- 03 -- -- 03


Course Code Course Name Credits
BMDO6011 Nuclear Medicine 03
Course O bject ives • To enable the students to understand the basic science of nuclear medicine,
operating principles and quality control aspects of various nuclear medicine
equipment.
• To keep the students abreast with the technological developments in the
field of nuclear medicine.
Course Outcomes Learners will be able to
• Explain the essential physics of nuclear medicine such as concepts of
radioactivity, its measurement, interaction with matter and radionuclide
production.
• Apply the principles of physics to understand working of various detectors
and counting systems.
• Study principle of operation of different scanning system and their quality
control function.
• Explain various Emission Tomography Techniques along with their Clinical
Applications.
• Explain various aspects of radiation safety.
• Explain concept of radionuclide therapy and t he function of radiotherapy
equipment.

Module Content Hours

1.
Basics of Nuclear Physics : Radioactivity, radioactive decay law, radioactive
decay processes, decay scheme of Mo -99. Units of radioactivity measurement,
interaction of radiation with matter
Production of Radionuclide:
Methods of radionuclide production: nuclear reactor, medical cyclotron &
radionuclide generators 09 Course
Code Course Name Examination Scheme
Theory
Term
work Pract Oral Pract.
/ Oral Total Internal
Assessment End
sem Dura
tion
(hrs) Test
1 Test
2 Avg.


BMDO
6011
Nuclear
Medicine
(Abbreviated
as NM) 20 20 20 80 03 -- -- -- -- 100

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University of Mumbai, Biomedical Engineering, Rev 202 1-22 Spectra of commonly used radio nuclides e.g Tc -99m, Cs -137.
Radiopharmaceuticals: ideal radiopharmaceutica l, methods of radio labelling

2.
Detectors in Nuclear Medicine & Counting and Measuring System:
Gas filled detectors, scintillation detectors and solid -state detectors, scintillation
counting system, gamma ray spectrometry, radionuclide dose calibr ator,
properties of detectors .
In Vitro Techniques (Brief Description):
Introduction, single and double isotope method, radioimmunoassay, RIA
counting system, liquid scintillation counting system , RIA applications. 07
3.
In Vivo Techniques:
General principle, uptake monitoring system, rectilinear scanner, gamma
camera fundamentals, position circuitry and working, computer interface,
performance parameters, quality control functions 06

4.
Emission Tomography Techniques and Clinical Applications :
Introduction, principles and applications of SPECT, principles and applications
of PET, system performance parameters and quality control functions .
Introduction to Hybrid Modalities:
PET/CT, SPECT/CT
Clinical Appl ications
Clinical applications of PET, SPECT and hybrid modalities in cardiology,
neurology and oncology. 07

5.
Radiation Safety:
Natural & artificial radiation exposure, external & internal radiation hazard,
methods of minimizing external exposure, methods of preventing internal
exposure, evaluation of external & internal hazard, biological effects of
radiation, radioactive waste manag ement. 06

6.
Radionuclide Therapy:
Choice of a radionuclide in therapeutic nuclear medicine , radiotherapy
equipment: cobalt unit, proton beam t herapy 04


Assessment:
Internal assessment consists of two tests out of which; one should be compulsory class test (on minimum 02
modules) and the other is either a class test or assignment on live problems or course project.


Books Recommended:
Text Books:
1. J. Harbert and A.F.G. Roc ha, Textbook of Nuclear medicine , Second Edition, Lea & Febiger.
2. B.R. Bairi, Balvinder Singh, N.C. Rathod and P.V. Narurkar, Handbook of Nuclear medicine
Instruments , Tata McGraw – Hill.
3. Gopal B. Saha, Fundamentals of Nuclear Pharmacy , Springer Scien ce + Business Media
4. Ramesh Chandra, Introductory Physics of Nuclear Medicine , Lea & Febiger.
5. Simon R. Cherry, James A. Sorenson and Michael E. Phelps, Physics in Nuclear Medicine , Saunders, an
imprint of Elsevier Inc.
6. Janet F. Eary and Winfried Brenner, Nuclear Medicine Therapy , informa healthcare

Reference Books:

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University of Mumbai, Biomedical Engineering, Rev 202 1-22 1. William R. Hendee, Medical Radiation Physics , Year Book Medical Publishers
2. G. Hine, Instrumentation of N uclear medicine , Academic Press
3. Glenn F. Knoll, Radiation Detection & Measurement , John Wiley & Sons.

NPTEL/Swayam Links:
Course 1: Nuclear Science and Engineering, Dr. Santanu Gosh, Indian institute of Technology, Delhi
https://nptel.ac.in/courses/115/102/115102017/

Theory Examination :
1. Question paper will comprise of 6 questions, each carrying 20 marks.
2. Total four questions need to be solved.
3. Q.1 will be compulsory, based on entire syllabus wherein sub questions of 2 to 5 marks will be asked.
4. Remaining question will be randomly select ed from all the modules.

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University of Mumbai, Biomedical Engineering, Rev 202 1-22 Course
Code Course Name Teaching scheme Credit assigned
BMDO
6012 Advanced
Embedded
Systems
(Abbreviated
as AES) Theory Pract. Tut. Theory Pract. Tut. Total
03 -- -- 03 -- -- 03


Course
Code Course Name Examination Scheme
Theory Term
work Pract. /
Oral Total
Internal Assessment End
Sem Duration
(Hrs.) Test 1 Test 2 Avg.
BMDO
6012 Advanced
Embedded
Systems
(Abbreviated
as AES) 20 20 20 80 03 -- -- 100


Course Code Course Name Credits
BMDO6012 Advanced Embedded Systems 03
Course Objectives • To impart the hardware and software concepts of Embedded System.
• To introduce the students with Real Time Operating System.
• To implement the embedded design, ARM Cortex M3 Microcontroller
is covered in detail.



Course Outcomes Learner will be able to:
• Explain the fundamentals of embedded systems
• Understand the characteristics and hardware of embedded system.
• Understand the software used for an embedded system.
• Understand interprocess communication.
• Understand the usage of the development and debugging tools.
• Explain the concept of Real Time Operating Systems (RTOS) using
practical cases.

Module Contents Hours
1. ARM Cortex M3 : Overview of ARM family, comparison of RISC and CISC
architectures.
Cortex -M3 architecture, pipelining, BUS interfaces
Programmers’ model: register set, program status register, operation modes and
states.
Memory system and memory protection unit (MPU).
Exceptions, interrupt architecture: Nested vectored interrupt controller,
power management, watchdog timer and systick timer. 08

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University of Mumbai, Biomedical Engineering, Rev 202 1-22 2. Introduction to Embedded Systems and Embedded Hardware:
characteristics and design metrics of embedded system, challenges in embedded
system design, embedded processors, co -processors and hardware accelerators.
Processor performance enhancement: pipelining and superscalar architecture.
Types of memories and buffers, sensors (optical encoders, resistive sensors)
and actuators (solenoid valves, relay/switch, opto -couplers).
Power supply considerations in embedded systems: linear and switching
voltage regulators, low power features, sleep mode, b rown -out detection. 06
3. Embedded Software – RTOS 01: Features of RTOS, advantages of RTOS,
hard and soft real time systems, selecting an RTOS, Kernel architectures and
features.
Task/Processes and threads, task states, multitasking, interrupt latency.
Context Switching: Cooperative multi-tasking and pre-emptive multi-tasking.
Task Scheduler: FIFO, round robin, rate-monotonic scheduling, earliest -
deadline first scheduling, fault-tolerant scheduling 08
4. Embedded Software – RTOS 02 : Inter-process communication: Semaphores
and signals, shared memory communication, message based communication.
Memory management , file systems, device management (device drivers), I/O
and communications managem ent.
Event timers, task synchronization, priority inversion, deadlock .
Software design methodologies: UML, FSM, DFG.
Evaluating and optimizing operating system performance: response -time
calculation, interrupt latency, time-loading, memory loading. 08
5. FreeRTOS : Study of Kernel structure of FreeRTOS, functions for
initialization, task creation, inter -task communication and resource
management, memory management.
System integration, testing and debugging methodology:
Embedded product desi gn life -cycle (EDLC),
Hardware -software co-design testing & debugging: Boundary -scan/JTAG
interface concepts, black-box testing, white-box testing. 05
6. Case studies: Chocolate vending machine, washing machine, automotive
systems, auto-focusing digital camera, air-conditioner. 04


Assessment:
Internal assessment consists of two tests out of which, one should be compulsory class test (on minimum
02 modules) and the other is either a class test or assignment on live problems or course project.

Books Recommended:
Text books :

1. Embedded Systems Architectu re Programming and Design: Raj Kamal, Tata McGraw Hill
2. Software Design for Real -Time Systems: Cooling, J E, published by Chapman and Hall in 1991 ...
ISBN 978 -0-442-31174 -2
3. Embedded System Design: A unified Hardware/software Introduction by Frankvahid/Tony
Givargis, Wiley India Edition
4. Real-Time Systems Design and Analysis: An Engineer's Handbook: Laplante, Phillip A by IEEE
press, Wiley -Interscience , A John Wiley and Sons Inc, Publications
5. Embedded / Real -Time Systems: Concepts, Design and Programming Black Book, New ed
(MISL -DT)

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University of Mumbai, Biomedical Engineering, Rev 202 1-22 Reference Books:
1. Embedded Realtime Systems Programming by Sriram Iyer and Pankaj Gupta, Tata McGraw Hill.
2. Dreamteach So ftware team, Programming for Embedded Systems, AVR 8515 manual
3. Bruce Powel Douglas, “Real -Time UML, Second Edition: Developing Efficient Object for
Embedded Systems, 2nd edition ,1999, Addison -Wesley
4. An Embedded Software Primer by David E. Simon - Pearson Education, 2003


Theory Examination:
1. Question paper will comprise of 6 questions, each carrying 20 marks.
2. Total four questions need to be solved.
3. Q.1 will be compulsory, based on entire syllabus wherein sub questions of 2 to 5 marks will be
asked.
4. Remaining question will be randomly selected from all the modules.

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University of Mumbai, Biomedical Engineering, Rev 202 1-22 Course Code Course Name Teaching Scheme
(Contact Hours) Credits Assigned
Theory Pract. /Tut. Theory Pract. Total
BMDO6013 Telemedicine
(Department
Optional Course -2) 3 -- 3 -- 3
Course Code Course Name Examination Scheme
Theory
Term
Work Prac/
oral Total Internal Assessment End
Sem
Exam Exam.
Duration
(in Hrs) Test1 Test
2 Avg
BMDO6013 Telemedicine
Department Optional
Course – 2 20 20 20 80 3 -- -- 100

Course Code Course Name Credits
BMDO601 3 Telemedicine 03
Course Objectives • Learn the key principles for telemedicine and e -health care.
• Understand telemedicine technology.
• Know telemedicine standards, mobile telemedicine, and its applications.
Course Outcomes Learner will be able to …
• Explain the basic principles of healthcare in telemedicine
• Discuss the role of telecommunication in Healthcare
• Describe various Tele -medicine standards.
• Explain the different Components of tele -radiology system
• Discuss the various applications of telemedicine

Module Contents Hours
1. Introduction to Telemedicine: Historical perspective and evolution of
telemedicine, tele health, tele care, components of telemedicine system, global and
indian scenario, ethical and legal aspects of telemedicine, safety and regulatory
issues, laws governing telemedicine. 07
2. Telem edicine Technology: Principles of multimedia – text, audio, video, data, data
communications and networks, PSTN, POTS, ANT, ISDN , internet, air /wireless
communications: GSM satellite, and micro wave, modulation techniques,
integration and operational issue s, communi cation infrastructure for telemedicine,
LAN and WAN technology, satellite communications, mobile hand held devices and
mobile communication, internet technology, video and audio conferencing, clinical
data - local and centralized 06
3. Telemedicine Standards: Data security and standards: encryption, cryptography,
mechanisms of encryption, phases of encryption .
Protocols: TCP/IP, ISO -OSI, standards to be followed DICOM, HL7, H.320 series
(video phone based ISBN) T.120, H.324 ( video phone based PSTN), Video
conferencing, real-time telemedicine integrating doctors / hospitals, clinical
laboratory data, radiological data, and other clinically significant biomedical data, 06

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University of Mumbai, Biomedical Engineering, Rev 202 1-22 administration of centralized medical data, security and confidentially of medical
records and access control, cyber laws related to telemedicine.
4. Mobile Based Tele -ECG: Need for mobile based TM, Tele -ECG development,
Tele ECG scenario on the globe, extension of mobile based approach for other vital
signals, cloud based tele-monitoring, personal monitoring, Impact of mobile based
Tele-ECG. 06
5. Mobile Telemedicine: Components of tele -radiology system: Image acquisition
system display system, tele pathology, multimedia databases, color images of
sufficient resolution, dynamic range, spatial resolution, compression methods,
interactive control of color, m edical information storage and management for
telemedicine - patient information medical history, test reports, medical images
diagnosis and treatment.
Hospital information system – doctors, paramedics, facilities available.
pharmaceutical information syst em. 07
6. Telemedicine Applications: Telemedicine access to health care services – health
educ ation and self -care. introduction to robotics surgery, tele -surgery. tele -
cardiology, telemedicine in neurosciences, electronic documentation, e -health
services security and interoperability., telemedicine access to health care services,
health education and self -care, business aspects – project planning, usage of
telem edicine. 07

Assessment:
Internal assessment consists of two tests out of which, one should be compulsory class test (on minimum
02 modules) and the other is either a class test or assignment on live problems or course project.

Text Books:
1. Norris, A.C. “Essentials of Telemedicine and Tele care”, Wiley (ISBN 0 -471-53151 -0), First
edition, 2002.
2. O’Carroll, P.W, Yasnoff W.A., Ward E.Ripp, L.H., Martin, E.L., “Public Health Informatics and
Information Systems”, Springer (ISBN 0 -387-95474 -0), 1st Edition, 2003.
3. Ferrer -Roca, O., Sosa -Iudicissa, M , “Handbook of Telemedicine”, IOS Press (Studies in Health
Technology and Informatics, Volume 54). (ISBN 90 -5199 -413-3), 3rd Edition, 2002.
Reference Books:
1. Simpson, W. “Video over IP - A practical guide to technology and applications”, Focal Press
(Elsevier). ISBN -10: 0 -240-80557 -7, 2006.
2. Wootton R. Craig, J., Patterson V. “Introduction to Telemedicine”, Royal Society of Medicine
Press Ltd (ISBN 1853156779), 2nd Edition, 2006.

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University of Mumbai, Biomedical Engineering, Rev 202 1-22




Course
Code Course Name Teaching scheme Credit assigned
BML601 Biomedical
Instrumentation -II
Laboratory
(Abbreviated as
BMI -II) Theory Pract. Tut. Theory Pract. Tut. Total
-- 02 -- -- 01 -- 01

Course
Code Course Name Examination Scheme
Theory
Term
work Pract. Oral Pract.
/ Oral Total Internal Assessment End
sem Test 1 Test 2 Avg.
BML601 Biomedical
Instrumentation -II
Laboratory
(BMI -II) -- -- -- -- 25 -- -- 25 50

Course Code Course Name Credits
BML601 Biomedical Instrumentation – II Laboratory 01
Course Objective • To understand the basic principles and working of patient monitoring system.
• To develop skills enabling Biomedical Engineers to serve the health care industry
• To develop core competency and skill in the field of Biomedical Engineering, to
design and develop new health care systems.
Course Outcome Learner will be able to …
• Design and Implement filters for filtering of noise from signals.
• Design and Implement Instrumentation amplifier to amplify low amplitude
signals.
• Design and Implment a regulated power supply.
• Design and Implement Pulse Width Modulator.
• Undesrtand the working of ECG machine by recording ECG.
• Provide a better understand ing about foetal monitoring systems.
• Test the hearing ability using an audiomet er.

Syllabus: Same as that of (BMC 601) Biomedical Instrumentation -II (BMI -II)

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University of Mumbai, Biomedical Engineering, Rev 202 1-22
List of Laboratory Experiments: (Any Seven)
1. Design of instrumentation amplifier
2. Implementation of notch filter
3. Implementation of bandpass filter
4. Design and implementation of regulated power supply
5. Demonstration of ECG machine / monitor
6. Demonstration of foetal monitor
7. Demonstration of blood flow measuremen t
8. Testing of hearing ability u sing audiometer
9. Industry / hospital visit may to be conducted
Any other experiment based on syllabus which will help learner to understand topic/concept.

Group Presentations on the latest technology in hospitals based on the topics covered in the syllabus.

Assessment:
Term Work:
Term work shall consist of minimum 7 experiments.
The distribution of marks for term work shall be as follows:
Laboratory work (Experiments) : 10 Marks
Laboratory work (Journal) : 5 Marks
Presentation : 5 Marks
Attendance : 5 Marks
The final certification and acceptance of term work ensures the satisfactory performance of laboratory
work and minimum passing in the term work.

Books Recommended:
Text books:
1. Handbook of Biomedical Instrumentation (Third edition): R S. Khandpur. (PH Pub)
2. Medical Instrumentation, Application and Design: J G. Webster. (John Wiley)
3. Biomedical Instrumentation and measurements: Leslie Cromwell, Fred J. Weibell, Enrich A. Pfeiffer.
(PHI Pub)

Reference books:
1. Introduction to Biomedical Equipment Technology: Carr –Brown. (PH Pub)
2. Encyclopedia of Medical Devices and Instrumentation: J G. Webster. Vol I - IV (PH Pub)
3. Various Instruments Manuals.
4. Various internet websites

Practical and Oral examination will be base d on suggested practical list and entire syllabus.

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University of Mumbai, Biomedical Engineering, Rev 202 1-22 Sub Code Subject
Name Teaching Scheme Credits Assigned
Theory Pract. Tut Theory Pract. Tut Total
BML602 Biomedical
Digital
Image
Processing
Laboratory --- 2 --- --- 1 --- 1

Sub Code Subject
Name Examination scheme
Theory Marks
Term
work Pract/
Oral Total Internal Assessment End
Sem
exam Exam
Dur in
hrs Test 1 Test 2 Avg.
BML602 Biomedical
Digital
Image
Processing
Laboratory --- --- --- --- --- 25 25 50


Course Code Course Name Credits
BML60 2 Biomedical Digital Image Processing Laboratory 01
Course
Objectives • To be able to think about applying different Image processing techniques on a
given image.
• To know the fundamental concepts of a digital image processing techniques
• To be able to analyze problem and design algorithms to solve the problems.
Course
Outcomes Learner will be able to …
• Acquire the fundamental concepts of a digital image processing system such as
image acquisition, enhancement, segment ation, transforms, compression,
morphology, representation and description.
• Analyze images in the spatial domain.
• Analyze images in the frequency domain through the Fourier transform.
• Apply the concepts of morphology, representation and description on ima ges.
• Design and implement with MATLAB/C/Python algorithms for digital image
processing.

Syllabus: Same as that of BMC602 Biomedical Digital Image Processing (Abbreviated as BDIP ).

List of Experiments (using Matlab / C / Labview / python / other platform)


1. Point processing techniques (At least 4 experiments)
2. Spatial domain filtering
3. Histogram processing (Histogram stretching, equalisation and matching)
4. Frequency domain filtering (Plotting 2D -DFT, low pass and high pass (Ideal, Butterworth and
Gaussian) filters

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University of Mumbai, Biomedical Engineering, Rev 202 1-22 5. Segmentation - gradient operators
6. Compression - JPEG
7. Morphology - dilation erosion

Any other experiment based on syllabus may be included, which would help the learner to understand
topic/concept.
Assessment :
Term Work :
Term work shall consist of minimum 8 experiments.
The distribution of marks for term work shall be as follows:
Laboratory work (Experiments) : 10 Marks
Laboratory work (Journal) : 10 Marks
Attendance : 5 Marks
The final certification and acceptan ce of term work ensures the satisfactory performance of laboratory work and
minimum passing in the term work.


Text books:
1. Digital Image Processing, Gonzalez and Woods - Pearson Education.
2. Fundamentals of Digital Image Processing, A.K. Jain – P.H.I.
3. Digital Image Processing and Analysis, Chanda Majumder - Printice Hall India.

Reference Books:
1. Digital Image Processing for Medical Applications, Geoff Dougherty, Cambridge University
Press, 20 09..
2. Digital Image Processing, William Pratt - John Wiley.

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University of Mumbai, Biomedical Engineering, Rev 202 1-22 Course
Code Course Name Teaching scheme Credit assigned
BML603 Data Analysis in
Healthcare
Laboratory Theory Pract. Tut. Theory Pract. Tut. Total
-- 02 -- -- 01 -- 01

Course
Code Course Name Examination Scheme
Theory Term
work Pract. Oral Pract.
/ Oral Total Internal Assessment End
sem Test 1 Test 2 Avg.
BML603 Data Analysis in
Healthcare
Laboratory -- -- -- -- 25 -- -- 25 50

Course Code Course Name Credits
BML603 Data Analysis in Healthcare Laboratory 01
Course Objective To conduct analysis of medical data using Statistical tools.
Course Outcome Learner will be able to
• Plan the experiment for the given study
• Form a sample of proper size
• Use descriptive statistics to present the data
• Apply statistical methods to analyse the data
• Make inferences based on statistical theories

Syllabus: Same as that of BML603 Data Analysis in Healthcare (DAH)
Laboratory experiments may be conducted using Excel/ Python / R Studio /Tableau or any other
Statistical tool/ s oftware

List of experiments
1. Descriptive statistics and probability
2. Discrete probability distributions
3. Continuous probability distributions
4. Sampling distributions
5. Estimation
6. Hypothesis testing
7. Analysis of variance
8. Regression and Correlation
9. Chi square distribution and analysis of frequency
10. Anova
11. Kruskal -Wallis Test
12. Mann Whitney U -test

Any other experimen t based on syllabus which will help students to understand topic/concept

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University of Mumbai, Biomedical Engineering, Rev 202 1-22 Assessment:
Term Work:
Term work shall consist of minimum 7 experiments.
The distribution of marks for term work shall be as follows:
Laboratory work (Experiments) : 10 Marks
Laboratory work (Journal) : 10 Marks
Attendance : 5 Marks
The final certification and acceptance of term work ensures the satisfactory performance of laboratory work
and minimum passing in the term work.

Books Recommended:
Text books:
1. Biostatistics – A foundation for analysis in health sciences by Wayne W. Dani el, Seventh edition, Wiley India
2. Fundamentals of mathematical statistics by S. C. Gupta and V. K. Kapoor, second edition, Sultan Chand Publisher
3. Probability and statistics for engineers by J. Ravichandran, Wiley India

Reference Books:
1. Biostatistics – How it works by Steve Selvin, Pearson education
2. An Introduction to Biostatistics by Sunder Rao and J. Richard, Third Edition, Prentice Hall of India
3. Probability and Statistics by Schaum’s series

NPTEL /Swayam Course:
Course :
Data Analysis and Decision Making - I by Prof. Raghunandan Sengupta, IIT Kanpur
https://nptel.ac.in/courses/110/104/110104094/
Descriptive Statistics with R Software By Prof. Shalabh, Prof. Prashant Jha IIT Kanpur, NIT Sikkim
https://onlinecourses.nptel.ac.in/noc21_ma37/preview


Oral examination will be based on suggested practical list and entire syllabus.

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University of Mumbai, Biomedical Engineering, Rev 202 1-22 Course
Code Course Name Teaching scheme Credit assigned
BML604 Patient -care
Automation
Laboratory Theory Pract. Tut. Theory Pract. Tut. Total
-- 02 -- -- 01 -- 01

Course
Code Course Name Examination Scheme
Theory Term
work Pract. Oral Pract.
/ Oral Total Internal Assessment End
sem Test 1 Test 2 Avg.
BML604 Patient -care
Automation
Laboratory -- -- -- -- 25 -- -- -- 25


Course Code Course Name Credits
BML604 Patient -care Automation Laboratory 01
Course
Objectives • To understand the fundamentals of automation and various components of automated
instrumentation systems used in patient care such as sensors, data acquisition, data
processing and visualization .
• To understand the working of these system s and should be able to determine hardware
and software requirements for the automated systems .
• To understand how to design any application based on these systems.
• To understand the requirements of patient safety and design safety instrumented
systems
Course
Outcomes Learner will be able to …
• Demonstrate the use of analog circuits in automation of biomedical instruments .
• Demonstrate the use of digital circuits in automation of biomedical instruments .
• Demonstrate and explain the working of automated patient care devices and
instrumentation by proper selection and designing criteria, developing user friendly
interfaces/GUI to make stand -alone biomedical instruments .
• Explain the need of patient safety and use of safety features and devices in designing
of the systems.

List of Experiments (any 7)
1. Conditional decision making and switching of output devices like relays/ motors
2. Usage of indicating components (displays/ LED/ alarms) in biomedical applications
3. Use of peristaltic pump for dispensing the doses
4. Design of heart rate measurement circuits using analog components
5. Design of low -cost body temperature measurement unit
6. Automation of rehabilitation devices using electronic/ mechanical components
7. Design s yringe pump driving circuit
8. User friendly user interfaces for biomedical equipment
9. Patient feedback designs using patient switch (audiometer)

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University of Mumbai, Biomedical Engineering, Rev 202 1-22 10. Patient safety using safety switch (traction machine)
11. Design and approaches for nerve and muscle stimulator using wave form generator s
12. Design of bio-signal transmission using modulation techniques
Note: The above experiments can be performed using the freeware or available simulation software
No single solution to any design and it depends on the available analog or digital resources.

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University of Mumbai, Biomedical Engineering, Rev 202 1-22 Assessment:
Term Work:
Term work shall consist of minimum 7 experiments.
The distribution of marks for term work shall be as follows:
Laboratory work (Experiments) : 10 Marks
Laboratory work (Journal) : 05 Marks
Presentation : 05 Marks
Attendance : 05 Marks
The final certification and acceptance of term work ensures the satisfactory performance of laboratory work and
minimum passing in the term work.
Books Recommended:
Text books:
1. Handbook of Biomedical Instrumentation (Third edition): R S. Khandpur. (PH Pub)
2. Medical Instrumentation, Application and Design: J G. Webster. (John Wiley)
3. Biomedical Instrumentation and Measurements: Leislie Cromwell, Fred J. Weibell, Enrich A. Pfeiffer. (PHI
Pub)

Reference books:
1. Introduction to Biomedical Equipment Technology: Carr – Brown. (PH Pub)
2. Encyclopedia of Medical Devices and Instrumentation: J G. Webster. Vol . I- IV (PH Pub)
3. Various Instruments Manuals.
4. Various internet websites

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University of Mumbai, Biomedical Engineering, Rev 202 1-22 Course code Course Name Credits
BMM6 01 Mini Project - 2 B 02

Course Code Course Name Credits
BMM601 Mini Project – 2 B 02
Course Objective • To acquaint with the process of identifying the needs and converting it into the
problem .
• To familiarize the process of solving the problem in a group .
• To acquaint with the process of applying basic engineering fundamental s to
attempt solutions to the problems.
• To inculcate the process of self -learning and research.
Course Outcome Learner will be able to:
• Identify problems based on societal /research needs.
• Apply Knowledge and skill to solve societal problems in a group.
• Develop interpersonal skills to work as member of a group or leader.
• Draw the proper inferences from available results through theoretical /
experimental/simulations .
• Analyse the impact of solutions in societal and environmental context for
sustainable development.
• Use standard norms of engineering practices
• Excel in written and oral communication.
• Demonstrate capabilities of self -learning in a group, which leads to life long
learning.
• Demonstrate project management principles during project work.

Guidelines for Mini Project
• Students shall form a group of 3 to 4 students, while forming a group shall not be allowed less than
three or more than four students, as it is a group ac tivity.
• Students should do survey and identify needs, which shall be converted into problem statement for
mini project in consultation with faculty supervisor/head of department/internal committee of
faculties.
• Students shall submit implementation plan in the form of Gantt/PERT/CPM chart, which will cover
weekly activity of mini project.
• A log book to be prepared by each group, wherein group can record weekly work progress,
guide/supervisor can verify and record notes/comments.
• Faculty supervisor may give inputs to students during mini project activity; however, focus shall be
on self -learning.
• Students in a group shall understand problem effectively, propose multiple solution and select best
possible solution in consultation with guide/ supervisor.
• Students sh all convert the best solution into working model using various components of their
domain areas and demonstrate.

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University of Mumbai, Biomedical Engineering, Rev 202 1-22 • The solution to be validated with proper justification and report to be compiled in standard format
of Un iversity of Mumbai .
• With the focus on the self -learning, innovation, addressing societal problems and entrepreneurship
quality development within the students through the Mini Projects, it is preferable that a single
project of appropriate level and quali ty to be carried out in two semesters by all the groups of the
students. i.e. Mini Project 1 in semester III and IV. Similarly, Mini Project 2 in semesters V and VI.
• However, based on the individual students or group capability, with the mentor’s recommen dations,
if the proposed Mini Project adhering to the qualitative aspects mentioned above gets completed in
odd semester, then that group can be allowed to work on the extension of the Mini Project with
suitable improvements/modifications or a completely n ew project idea in even semester. This policy
can be adopted on case by case basis.
Guidelines for Assessment of Mini Project :
Term Work
• The review/ progress monitoring committee shall be constituted by head of departments of
each institute. The progress of mini project to be evaluated on continuous basis, minimum two
reviews in each semester.
• In continuous assessment focus shall also be on each individual student, assessment based on
individual’s contribution in group activity, their understandin g and response to questions.
• Distribution of Term work marks for both semesters shall be as below;
o Marks awarded by guide/supervisor based on log book : 10
o Marks awarded by review committee : 10
o Quality of Project report : 05
Review/progress moni toring committee may consider following points for
assessment based on either one year or half year project as mentioned in general
guidelines.
One-year project:
• In first semester entire theoretical solution shall be ready, including components/system
selection and cost analysis. Two reviews will be conducted based on presentation given by
students group.
▪ First shall be for finalisation of problem
▪ Second shall be on finalisation of proposed solution of problem.
• In second semester expected work shall be procurement of component’s/systems, building of
working prototype, testing and validation of results based on work completed in an earlier
semester.
▪ First review is based on readiness of building working prototype to be conducted.
▪ Second review shall be ba sed on poster presentation cum demonstration of working
model in last month of the said semester.

Half -year project:
• In this case in one semester students’ group shall complete project in all aspects including,
o Identification of need/problem
o Proposed fin al solution
o Procurement of components/systems

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University of Mumbai, Biomedical Engineering, Rev 202 1-22 o Building prototype and testing
• Two reviews will be conducted for continuous assessment,
▪ First shall be for finalisation of problem and proposed solution
▪ Second shall be for implementation and testing of soluti on.

Assessment criteria of Mini Project.

Mini Project shall be assessed based on following criteria;
1. Quality of survey/ need identification
2. Clarity of Problem definition based on need.
3. Innovativeness in solutions
4. Feasibility of proposed problem solutions and selection of best solution
5. Cost effectiveness
6. Societal impact
7. Innovativeness
8. Cost effectiveness and Societal impact
9. Full functioning of working model as per stated requirements
10. Effective use of skill sets
11. Effective use of standard engineering norms
12. Contribution of an individual’s as member or leader
13. Clarity in written and oral communication

• In one year, project , first semester evaluation may be based on first six criteria’s and remaining
may be used for second semester evaluation of performance of students in mini project .
• In case of half year project all criteria’s in generic may be considered for evaluation of performance
of students in mini project.
Guidelines for Assessment of Mini Project Practical/Oral Examination:
• Report should be prepared as per the guidelines issued by the University of Mumbai.
• Mini Project sh all be assessed through a presentation and demonstration of working model by the
student project group to a panel of Internal and External Examiners prefera bly from industry or
research organisations having experience of more than five years approved by head of Institution.
• Students shall be motivated to publish a paper based on the work in Conferences/students
competitions.
Mini Project shall be assessed based on following points;
1. Quality of problem and Clarity
2. Innovativeness in solutions
3. Cost effectiveness and Societal impact
4. Full functioning of working model as per stated requirements
5. Effective use of skill sets
6. Effective use of standa rd engineering norms
7. Contribution of an individual’s as member or leader
8. Clarity in written and oral communication