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BVOC Pharma analytical Science_1 Syllabus Mumbai University by munotes
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AC 24 -06-2016
Item No. 4.65
UNIVERSITY OF MUMBAI
Syllabus for the F.Y., S.Y. and T.Y. B.Voc
Program: B.Voc
Course : PHARMA ANALYTICAL
SCIENCES
(To be Introduced Choice Based Credit System with
effect from the academic year 2016 -17)
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Preamble:
Indian Pharmaceutical industry:
India accounts for 7% of the GDP by chemical sector and 11% of the national export. There are about 20000
registered pharmaceutical units in India and there are about 250 large units, 8000 small scale units and 5 central public sector units. Additionally, the size of the Indian diagnostic and lab services is about 160 billion.
Not marred by recession or inflation, the pharma sector has a competitive advantage of prospering steadily
and thus attracts lots of young professionals looking at pharmaceutical as their prospective career option.
With the expected growth rate of 14% per annum, Indian Pharmaceutical sector is expected to create more jobs in India in near future and add 45,000 fresh openings to its current strength. Since 2009- 10 more than 900 new drug approvals have been given by the Indian drug regulator. The
regulatory guidelines have been revised since the Supreme Court directives in 2011 -12. Regulatory
requirements are increasing in production, quality control and R & D laboratories. Therefore, the regulatory
department in a Pharmaceutical company not only needs a very broad understanding of the regulatory requirements but also must understand the chemical processes of production and quality control, the analytical tests, the pre -clinical stud ies and the clinical trial reports. Further there is an international strategy
to harmonize the guidelines using ICH. With about 25 leading pharmaceuticals and about 100 smaller units involved in exports the requirement of regulatory executives is constantly increasing. Some of the top Indian pharmaceuticals have more than 75 executives employed in the regulatory department alone.
The need to develop trained employable human resource:
The Indian Pharmaceutical and Chemical Industry have always been experiencing a dearth of skilled and industrially oriented human resource. The Industry despite employing students from chemistry, biology and pharmacy background always spends 6 months to one year for training the students for general industry needs like Good Laboratory Practices, Good Documentation Practices and regulatory compliances. The
important component of knowledge and implementation of quality in laboratory analysis is scarce in the graduates of chemistry and pharmacy. The skilled manpower requirement is in the areas of R & D, quality assurance and intellectual property. The Pharmaceutical industry sector in India is the one of the strong Export oriented sectors that needs to comply with a multitude of regulatory compliances for marketing the drug formulations abroad. In India itself, the sector needs to comply to stringent regulatory compliances and audits before the drug formulations are marketed. The training in practice of GLP as per the current regulatory requirements is missing. This course will provide manpower that is work- ready.
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Objectives of the Course
The course will address the requirements of conducting, managing and meeting regulatory
requirements for R & D and testing laboratories in pharmaceutical and chemical industries. Major hurdle faced
by the R&D centers at various Pharma laboratories is the lack of adequately trained and GLP oriented
personnel. This forms a major setback when the application of sophisticated technology especially in the bio
analytical field is concern ed. The lacunae become more evident when dealing with newer dosage forms and
peptide based drugs. This lacunae needs to addressed very diligently and the proposed programme is a step in
this direction
The program will have the following objectives ;
• To develop trained manpower in the field of Pharma Analytical Sciences with specific emphasis for
instrumentation skills needed for analysis
• To amalgamate knowledge of classical analytical techniques with modern sophisticated instrumentation
and provide trainin g in the analysis of chemicals, drugs, food and other products.
• To introduce the training with powerful tools of instrumentation analysis in routine analysis at
manufacturing, QC and research
• To provide exposure to National & International regulatory requ irements with reference to drugs and
chemicals
• To provide training in skills of analysis and develop knowledgeable and employable human resource
• To provide training in soft skills for efficient communication, technical writing, entrepreneurship and
basic business management,
O._______ Eligibility :
• Higher Secondary School Certificate (10 + 2), Science or its equivalent.
• No age bar
R.________ Duration: SIX semesters (Three Years)
R.________ No of Lectures: 7 theory papers each semester equivalent to 2 credits each.
30 lectures for each paper per semester.
R.________ No of Practical periods: 2 practical papers each semester equivalent to 10 credits each.
300 hours for each practical per semester.
R.________ No. of credits: 18 credits of Skill component and 12 credits of general education component
at each semester. Total 30 credits per semester.
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Work Load : Two periods per week per paper where each period is of
ONE hour duration
Twenty practical per week . Each practical is of Four periods
where each period is of ONE hour duration.
One Seminar / assignment per Week. Each seminar is of ONE hour
Guidance to the students for assignments / projects /
industrial visits / industrial training.
R.________ Passing Standard : Minimum 25 % marks in each paper and each practical
and minimum 40 % marks in aggregate in Theory
and Practical separately.
Number of Students 15 per batch
R. ________ The following will be the staffing pattern for the course;
• Instrument technician – 01
• Technical Assistant – 02
• Teaching staff – 03 (full time)
and remaining workload to be completed using guest faculty.
Faculty
Post-graduate degree in the subject of Chemistry / Botany / Zoology,
Microbiology / Biochemistry / Biotechnology with B+ and NET / SET as per the
current University guidelines
Visiting Faculty from Industry & Research Institutes
The visiting Faculty will be from a post equivalent to that of Associate Professor level with Ph. D
and not less than 5 years of research experience or with experience in industry not below
Assistant Manager Level.
R._________ Mark- list
• The mark -list of the students must indicate titles of papers in the syllabus
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R.________ details of the Syllabus
University of Mumbai
Credit Based, Semester & Grading System
SYLLABUS IN BRIEF : B.VOC , PHARMA ANALYTICAL SCIENCES :
Semester - I
Code Paper Credits Lectures L/Wk
Skill Component
UVPAS101 Preparation of standard solutions and
reagents 2 30 2
UVPAS102 Analytical applications of molecules and
molecular Interactions 2 30 2
UVPAS103 Applied physical principles in
instrumentation 2 30 2
UVPAS104 Introduction to data , data collection (sampling) and computation 2 30 2
UVPASP101 Practical based on Skill Components
Industrial visits and assignments 10 300 10
General Education Component
UVPAS105 Basic Chemistry and Chemical Interactions 2 30 2
UVPAS106 Chemistry and properties of solutes, solvents and solutions 2 30 2
UVPAS107 Skills of speaking and listening skills in
communication 2 30 2
UVPASP102 Practical based on General Education Components 10 300 10
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University of Mumbai
Credit Based, Semester & Grading System
SYLLABUS IN BRIEF : B.VOC , PHARMA ANALYTICAL SCIENCES :
Semester - II
Code Paper Credits Lectures L/Wk
Skill Component
UVPAS201 Preparation of standard solutions and
reagents - 2 2 30 2
UVPAS202 Analytical applications of molecules and
molecular Interactions - 2 2 30 2
UVPAS203 Applied physical principles in instrumentation - 2 2 30 2
UVPAS204 Introduction to data , data collection (sampling) and computation - 2 2 30 2
UVPASP201 Practical based on Skill Components
Industrial visits and assignments 10 300 10
General Education Component
UVPAS205 Basic Chemistry and Chemical
Interactions - 2 2 30 2
UVPAS206 Chemistry and properties of solutes, solvents and solutions - 2 2 30 2
UVPAS207 Skills of speaking and listening skills in communication - 2 2 30 2
UVPASP202 Practical based on General Education Components 10 300 10
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University of Mumbai
Credit Based, Semester & Grading System
SYLLABUS IN BRIEF : B.VOC , PHARMA ANALYTICAL SCIENCES :
Semester - III
Code Paper Credits Lectures L/Wk
Skill Component
UVPAS301 Basic techniques of recording laboratory
data for QA 2 30 2
UVPAS302 Basics of separation techniques and
laboratory analysis 2 30 2
UVPAS303 Sample preparation, storage and extraction techniques 2 30 2
UVPAS304 Statistical Evaluation and Data Management 2 30 2
UVPASP301 Practical based on Skill Components
Industrial visits and assignments 10 300 10
General Education Component
UVPAS305 Interactions between solutes, solvents & matrix components 2 30 2
UVPAS306 Analytical techniques for organic Compounds and natural products 2 30 2
UVPAS307 Skills of Technical writing and laboratory automation 2 30 2
UVPASP302 Practical based on General Education Components 10 300 10
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University of Mumbai
Credit Based, Semester & Grading System
SYLLABUS IN BRIEF : B.VOC , PHARMA ANALYTICAL SCIENCES :
Semester - IV
Code Paper Credits Lectures L/Wk
Skill Component
UVPAS401 Basic techniques of recording laboratory
data for QA – 2 2 30 2
UVPAS402 Basics of separation techniques and
laboratory analysis – 2 2 30 2
UVPAS403 Sample preparation, storage and extraction techniques – 2 2 30 2
UVPAS404 Statistical Evaluation and Data Management – 2 2 30 2
UVPASP401 Practical based on Skill Components
Industrial visits and assignments 10 300 10
General Education Component
UVPAS405 Interactions between solutes, solvents & matrix components – 2 2 30 2
UVPAS406 Analytical techniques for organic Compounds and natural products – 2 2 30 2
UVPAS407 Skills of Technical writing and laboratory automation – 2 2 30 2
UVPASP402 Practical based on General Education Components 10 300 10
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University of Mumbai
Credit Based, Semester & Grading System
SYLLABUS IN BRIEF : B.VOC , PHARMA ANALYTICAL SCIENCES :
Semester - V
Code Paper Credits Lectures L/Wk
Skill Component
UVPAS501 Analysis of samples of food, cosmetics
and drugs 2 30 2
UVPAS502 Advanced techniques of analysis 2 30 2
UVPAS503 Automation of laboratory data and their
management 2 30 2
UVPAS504 Industrial Training/Internship /project assignments 2 30 2
UVPASP501 Practical based on Skill Components
Industrial visits and assignments 10 300 10
General Education Component
UVPAS305 Applied molecular biology in analysis 2 30 2
UVPAS506 Pharmaceutical biochemistry and applications 2 30 2
UVPAS507 Entrepreneurship skills and project
management 2 30 2
UVPASP502 Practical based on General Education Components 10 300 10
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University of Mumbai
Credit Based, Semester & Grading System
SYLLABUS IN BRIEF : B.VOC , PHARMA ANALYTICAL SCIENCES :
Semester - VI
Code Paper Credits Lectures L/Wk
Skill Component
UVPAS601 Analysis of samples of food, cosmetics
and drugs – 2 2 30 2
UVPAS602 Advanced techniques of analysis – 2 2 30 2
UVPAS603 Automation of laboratory data and their
management - 2 2 30 2
UVPAS604 Industrial Training/Internship /project
assignments – 2 2 30 2
UVPASP601 Practical based on Skill Components
Industrial visits and assignments 10 300 10
General Education Component
UVPAS605 Applied molecular biology in analysis – 2 2 30 2
UVPAS606 Pharmaceutical biochemistry and applications – 2 2 30 2
UVPAS607 Entrepreneurship skills and project management – 2 2 30 2
UVPASP602 Practical based on General Education Components – 2 10 300 10
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Code Paper Credits Lectures L/Wk
Skill Component
UVPAS101 Preparation of standard solutions and
reagents 2 30 2
• Units of weights and
measurements – concept of
normality, molarity and molality
• Concept of standard solution and
their applications
UVPAS102 Analytical applications of molecules and
molecular Interactions 2 30 2
• Concept of atomic mass, atomic
number, isotopes and isomers
• Concept of Ka, Kb and Km
(enzymes) and their applications
UVPAS103 Applied physical principles in
instrumentation 2 30 2
• Concept of electromagnetic
spectrum and applications related
to various spectral regions
• Concept of Dispersion of light and scattering of light and their
applications
UVPAS104 Introduction to data , data collection
(sampling) and computation 2 30 2
• Concept of sample , sample
statistic and population statistics
• Basic Sampling techniques and
their application in pharma
UVPASP101 Practical based on Skill Components
Industrial visits and assignments 10 300 10
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Code Paper Credits Lectures L/Wk
General Education Component
UVPAS105 Basic Chemistry and Chemical
Interactions 2 30 2
• Atomic Structure, Molecules and
ions
• Chemical Bonds and Chemical
Reactions
UVPAS106 Chemistry and properties of solutes,
solvents and solutions 2 30 2
• Concept of solubility, partition and
their applications
• Water as a universal solvent in
living systems
UVPAS107 Skills of speaking and listening skills in
communication 2 30 2
• General inter personal
communications
• General official communications
UVPASP102 Practical based on General Education
Components 10 300 10
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Code Paper Credits Lectures L/Wk
Skill Component
UVPAS201 Preparation of standard solutions and
reagents - 2 2 30 2
• Principles in the use of indicators,
colour reagents and derivatizing
agents
• Dilutions and dilution techniques
and their applications
UVPAS202 Analytical applications of molecules and
molecular Interactions - 2 2 30 2
• Chemical reactions and
equilibrium
• Radioisotopes, labeled/tagged
probes in bioanalysis (including
ELISA)
UVPAS203 Applied physical principles in
instrumentation - 2 2 30 2
• Various properties of light and
their applications in measurement
• Concept of monochromatic light,
LASER and their uses
UVPAS204 Introduction to data , data collection
(sampling) and computation - 2 2 30 2
• Concepts of Quantitative data,
qualitative data and their statistical evaluation
• Applications of various data
representation techniques
UVPASP201 Practical based on Skill Components
Industrial visits and assignments 10 300 10
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Code Paper Credits Lectures L/Wk
General Education Component
UVPAS205 Basic Chemistry and Chemical
Interactions - 2 2 30 2
• Catalysts and their roles in
reactions
• Basic Concepts of enzymes and enzymatic reactions
UVPAS206 Chemistry and properties of solutes,
solvents and solutions - 2 2 30 2
• Properties of solvents and their
applications
• Concept of pH, buffers and their
applications
UVPAS207 Skills of speaking and listening skills in
communication - 2 2 30 2
• Techniques of effective
expression of ideas
• General written communications
UVPASP202 Practical based on General Education
Components 10 300 10
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Code Paper Credits Lectures L/Wk
Skill Component
UVPAS301 Basic techniques of recording laboratory
data for QA 2 30 2
• Concepts of QA and QC and their
significance
• GLP and its practice
UVPAS302 Basics of separation techniques and
laboratory analysis 2 30 2
• Types of chromatographic
separations and their applications
• Introduction to separation
techniques other than
chromatography
UVPAS303 Sample preparation, storage and
extraction techniques 2 30 2
• Sample storage and sample
processing
• Various extraction techniques and
their role in separation
UVPAS304 Statistical Evaluation and Data Management 2 30 2
• Data analysis for sample statistics
• Concept of sample size and its importance in managing
variability
UVPASP301 Practical based on Skill Components
Industrial visits and assignments 10 300 10
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Code Paper Credits Lectures L/Wk
General Education Component
UVPAS305 Interactions between solutes, solvents &
matrix components 2 30 2
• Partition coefficient and its
applications
• Selection of methods based on
different matrices
UVPAS306 Analytical techniques for organic
Compounds and natural products 2 30 2
• Analytical techniques involving
biological matrices and
macromolecules
• Analysis based on various
properties of organic compounds
and macromolecules
UVPAS307 Skills of Technical writing and laboratory
automation 2 30 2
• Test reports and their formats
• Autosamplers as simple
automation devices
UVPASP302 Practical based on General Education Components 10 300 10
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Code Paper Credits Lectures L/Wk
Skill Component
UVPAS401 Basic techniques of recording laboratory
data for QA – 2 2 30 2
• Concept of TQM and role of
analyst
• Quality of data and significance of
data integrity
UVPAS402 Basics of separation techniques and
laboratory analysis – 2 2 30 2
• Instrumentation and their working
in Chromatographic separation
• Instrumentation and their working
in separation techniques other
than chromatography
UVPAS403 Sample preparation, storage and
extraction techniques – 2 2 30 2
• Sample pre -treatment techniques
• Solid phase extraction &
automation in sample treatment
UVPAS404 Statistical Evaluation and Data Management – 2 2 30 2
• Comparison of samples
• Concept of significance and
confidence intervals
UVPASP401 Practical based on Skill Components
Industrial visits and assignments 10 300 10
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Code Paper Credits Lectures L/Wk
General Education Component
UVPAS405 Interactions between solutes, solvents &
matrix components – 2 2 30 2
• Concept of resolution, selectivity
and specificity of analysis
• Importance of solute- solvent
interaction in various analysis
UVPAS406 Analytical techniques for organic
Compounds and natural products – 2 2 30 2
• Analytical techniques for
minerals , oils and phytochemicals
• Analytical techniques for
polymers, dyes and pesticides
UVPAS407 Skills of Technical writing and laboratory automation – 2 2 30 2
• Technical writing styles and
reports
• Liquid handing systems and
automated work stations
UVPASP402 Practical based on General Education Components 10 300 10
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Code Paper Credits Lectures L/Wk
Skill Component
UVPAS501 Analysis of samples of food, cosmetics
and drugs 2 30 2
• Analytical techniques for food
products
• Various analytical techniques for
of drugs and cosmetics
UVPAS502 Advanced techniques of analysis 2 30 2
• Hyphenated techniques in
analysis - 1
• Applications of atomic properties
for analysis - 1
UVPAS503 Automation of laboratory data and their
management 2 30 2
• Laboratory information systems
and their significance
• E-records and their management
UVPAS504 Industrial Training/Internship /project assignments 2 30 2
• Students will be completing an
assignment at an industrial unit
(min 45 days)
UVPASP501 Practical based on Skill Components
Industrial visits and assignments 10 300 10
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Code Paper Credits Lectures L/Wk
General Education Component
UVPAS5 05 Applied molecular biology in analysis 2 30 2
• PCR and its applications
• Restriction enzymes and their
applications
UVPAS506 Pharmaceutical biochemistry and
applications 2 30 2
• Different pharmaceutical
preparations and their applications
• Analysis of excipents and their
significance
UVPAS507 Entrepreneurship skills and project management 2 30 2
• Initiating and sustaining start -up
projects in analytical services
• Planning and financing start -up
projects
UVPASP502 Practical based on General Education Components 10 300 10
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Code Paper Credits Lectures L/Wk
Skill Component
UVPAS601 Analysis of samples of food, cosmetics
and drugs – 2 2 30 2
• Residue analysis in finished
products
• Regulatory analysis of consumer
products
UVPAS602 Advanced techniques of analysis – 2 2 30 2
• Hyphenated techniques in
analysis – 2
• Applications of atomic properties
for analysis – 2
UVPAS603 Automation of laboratory data and their
management – 2 2 30 2
• Compliance to CFR part 11
• Data integrity, security and
archival
UVPAS604 Industrial Training/Internship /project assignments – 2 2 30 2
• Students will be completing an
assignment at an industrial unit
(min 45 days)
UVPASP601 Practical based on Skill Components
Industrial visits and assignments 10 300 10
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Code Paper Credits Lectures L/Wk
General Education Component
UVPAS605 Applied molecular biology in analysis – 2 2 30 2
• Nano particles and their
applications
• Techniques in proteomics
UVPAS606 Pharmaceutical biochemistry and applications – 2 2 30 2
• Drug delivery systems and their
applications
• Analytical approach to
standardising drug delivery
systems
UVPAS607 Entrepreneurship skills and project
management – 2 2 30 2
• Management project timelines
and deliveries
• Management of finances and
other resources
UVPASP602 Practical based on General Education Components – 2 10 300 10
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BVoc – Pharama Analytical Sciences
LIST OF PRACTICAL – TO BE COVERED IN SIX SEMESTERS
Practical:
Orientation practical : It will include introduction to
Indian Pharmacopoeia, its parts, its use in the context
of drugs and cosmetic act
1. Preparation of Normal solution, molar solution, molal solution
2. Identification of Laboratory glassware & Micropipetting
3. Use of Analytical balance, Monopan balance & calibrated weight box
4. Washing of laboratory glass ware chromic Acid preparation & use
5. Introduction, Lab note book, dress code, safety shower etc.
6. Instrument Identification, Usage logs, SOP, Calibration / Maintenance
Records, IQ, OQ, PQ concepts
7. Distilled Water & distillation unit
8. Calibration & Preventive maintenance -- Balance, micropipette, pH
meter, Colorimeter, Muffale furnace
9. Recording of Temperature & Humidity.
10. COA & documentation for sample identification & record
11. a) Stability chamber & its use
b) Deep freezers - -20°C, -85° & their usage
12. Preparation of PO4 buffer & bicarbonate buffer
13. Preparati on of Mobile phase for chromatography (use of separating
Funnel )
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14. Paper chromatographic separation of Amino acids, formulation: -
15. TLC on glass plate for fatty acids with iodine vapour visualization
16. Al. plate TLC for various compounds
a) Direct visualization
b) derivatisation
c) uv visualization
17. Identification of best filter for colorimetry of given colored solution
18. Identification of T max of given sample (demonstration & interpretation
of Spectrogram)
19. Tabet - Physical assays – Uniformity of wt
20. - Hardness
21. - friability
22. Total Ash,
23. Total organic content
24. Alcohol soluble, water soluble, Acid in soluble – etc (Proximate)
25. ELISA & its Usage
26. Colorimetric Estimation of glucose
27. Colorimetric estimation of – from formulation
28. Calculation of Mean, SD, C V
29. Graphical re- presentation
30. Calculation of A N O V A, student t test
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31. Scatter diagram, Trend line, regression equation & correlation
Coefficient
32. Audit of laboratory notes
33. Laboratory Safety signs & meaning, making laboratory signs
34. Fire fighting – usage of fire Extinguisher & its types
35. Waste disposal bags, colors & meanings – Biohazard waste
36. Use of Scientific calculator Logarithm, Antilog, Mean & SD
37. Assignment of
a) Microsoft Power Point
b) Microsoft EXCEL
c) Microsoft Word & Conversion of PDF 38. – Filling of requisition Form,
-- Letter for Plasma
-- Spirit License & renewal
-- Request of Bio Waste disposal
-- Bio waste disposal – Agreement
39. Volumetric titration
- Acid base
- Precipitation
- With Eriochome black T - indicter
- with pH meter
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- Thermometer
- Semi micro analysis
- Organic Analysis
- Volumetric Glass ware & sieves
- Powder analysis
- Syrup – Viscosity
- Refractive Index
- Specific gravity
- Absorbence of – Water holding capacity
- Estim ation of Moisture
- Acid value
- Saponification Value
- Iodine value
- Peroxide value
- Unsaponifiable matter
- Vitamin Assay
- Closure for injections
- Sterilization method
- Indicators
-- Reference Substance
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Basic Skills in Analytical Techniques and Practical Skills in following
aspects of various analytical instruments:
o Instrumentation
o Working
o Sample Processing
o Analysis, On -Line trouble shooting
o Reporting
o Documentations
• IR Spectroscopy , FTIR
• HPTLC
• HPLC
• GC
• Introduction to CE
• Introduction to MS and Hyphenated techniques – LC-MS, GC -MS
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The Scheme of Examination and Allotment of marks are tabulated below;
B. VOC. (PHARMACEUTICAL ANALYSIS)
FIRST YEAR (1000 MARKS PER SEMESTER)
THEORY
PRACTICAL
CODE MARKS (75:25) SCHEME CODE MARKS
UVPAS 101 SC-1 80 60:20
UVPASP 101 SP-1 100
UVPAS 102 SC-2 80 60:20 SP-2 100
UVPAS 103 SC-3 80 60:20 SP-3 100
UVPAS 104 SC-4 80 60:20 SP-4 100
UVPAS 105 GC-1 30 23:07 UVPASP 102 GC-1 100
UVPAS 106 GC-2 30 23:07 GC-2 100
UVPAS 107 GC-3 20 15:05
TOTAL MARKS 400 600
GRAND TOTAL 1000
NOTE : SC= Skilled Component, GC= General Component
B. VOC. (PHARMACEUTICAL ANALYSIS)
SECOND YEAR (1000 MARKS PER SEMESTER)
THEORY
PRACTICAL
CODE MARKS (75:25) SCHEME CODE MARKS
UVPAS 201 SC-1 80 60:20
UVPASP 201 SP-1 100
UVPAS 202 SC-2 80 60:20 SP-2 100
UVPAS 203 SC-3 80 60:20 SP-3 100
UVPAS 204 SC-4 80 60:20 SP-4 100
UVPAS 205 GC-1 30 23:07 UVPASP 202 GC-1 100
UVPAS 206 GC-2 30 23:07 GC-2 100
UVPAS 207 GC-3 20 15:05
TOTAL MARKS 400 600
GRAND TOTAL 1000
NOTE : SC= Skilled Component, GC= General Component
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B. VOC. (PHARMACEUTICAL ANALYSIS)
THIRD YEAR (800 MARKS PER SEMESTER)
THEORY
PRACTICAL
CODE MARKS (75:25) SCHEME CODE MARKS
UVPAS 301 SC-1 80 60:20
UVPASP 301 SC-1 120
UVPAS 302 SC-2 80 60:20 SC-2 120
UVPAS 303 SC-3 80 60:20 SC-3 120
UVPAS 304 GC-1 80 25:15 UVPASP 302 GC-1 120
TOTAL MARKS 320 480
GRAND TOTAL 800
NOTE : SC= Skilled Component, GC= General Component
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